Ro 20-0657/000-d3
Based on 1 Customer Validation
Ro 20-0657/000-d3 is the deuterium labeled Ro 20-0657/000 (HY-100622). Ro 20-0657/000 is a metabolite of Trimethoprim. Trimethoprim is a dihydrofolate reductase inhibitor, used as an antibacterial agent in human and veterinary medicine.
For research use only. We do not sell to patients.
- Formula: C14H15D3N4O4
- Molecular Weight:309.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 29606-06-2
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Molecular Weight 309.34
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Formula C14H15D3N4O4
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SMILES
OC(C1=C(N)N=C(N)N=C1)C2=CC(OC)=C(OC([2H])([2H])[2H])C(OC)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[2]. van 't Klooster GA, et al. Determination of trimethoprim and its oxidative metabolites in cell culture media and microsomal incubation mixtures by high-performance liquid chromatography. J Chromatogr. 1992 Sep 2;579(2):354-60. [Content Brief]
[3]. Tadić Đ, et al. Simultaneous determination of multiclass antibiotics and their metabolites in four types of field-grown vegetables. Anal Bioanal Chem. 2019 Aug;411(20):5209-5222. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ro 20-0657/000-d3 Related Classifications
HY-W707099 Related Classifications
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