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Cat. No.: HY-P10924

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Roseltide rT1

Roseltide rT1 is a neutrophil elastase inhibitor (IC₅₀=0.47 μM) rich in cysteine and one of the Roseltide (rT1-rT8) family members. Roseltide rT1 improves cAMP accumulation stimulated by neutrophil elastase in vitro, showing potential for inhibiting related diseases.

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CAS No.: 2206692-95-5
화학식: C₁₁₀H₁₇₇N₃₁O₃₁S₆
분자량:2622.16

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Roseltide rT1 Chemical Structure

CAS No.: 2206692-95-5

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

Chemical Information

CAS No. 2206692-95-5
분자량 2622.16
화학식 C₁₁₀H₁₇₇N₃₁O₃₁S₆
Sequence

Cys-Ile-Pro-Arg-Gly-Gly-Ile-Cys-Leu-Val-Ala-Leu-Ser-Gly-Cys-Cys-Asn-Ser-Pro-Gly-Cys-Ile-Phe-Gly-Ile-Cys-Ala (Disulfide bridge: Cys1-Cys16, Cys8-Cys21, Cys15-Cys26)
Sequence Shortening

CIPRGGICLVALSGCCNSPGCIFGICA (Disulfide bridge: Cys1-Cys16, Cys8-Cys21, Cys15-Cys26)
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocol

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (258 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Loo S, et al. Identification and Characterization of Roseltide, a Knottin-type Neutrophil Elastase Inhibitor Derived from Hibiscus sabdariffa. Sci Rep. 2016 Dec 19;6:39401. [Content Brief]

Calculators

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Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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