1. Protein Tyrosine Kinase/RTK
  2. TAM Receptor
  3. RU-301

RU-301 

Cat. No.: HY-119039
Handling Instructions

RU-301 is a pan-TAM receptor inhibitor, exerts pan-TAM inhibitory activity by binding at the interface between Gas6 and the Ig1 domain of the respective TAMs with Kd and IC50 values of 12 μM and 10 μM, respectively.

For research use only. We do not sell to patients.

RU-301 Chemical Structure

RU-301 Chemical Structure

CAS No. : 1110873-99-8

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Description

RU-301 is a pan-TAM receptor inhibitor, exerts pan-TAM inhibitory activity by binding at the interface between Gas6 and the Ig1 domain of the respective TAMs with Kd and IC50 values of 12 μM and 10 μM, respectively[1].

IC50 & Target

IC50: 10 μM (TAM)[1]

Molecular Weight

480.46

Formula

C₂₁H₁₉F₃N₄O₄S

CAS No.

1110873-99-8

SMILES

O=C(NCCNC1=CC=C(C(F)(F)F)C=C1[N+]([O-])=O)C2=CC=CC=C2SCC3=CC(C)=NO3

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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RU-301
Cat. No.:
HY-119039
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