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製品番号: HY-N19135

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SB87-H

SB87-H is a Pestalone-type benzophenone compound that exists in the endophytic fungus Pestalotiopsis trachicarpicola SC-J551 and the lichen endophytic fungus Pestalotiopsis rhododendri LF-19-12. SB87-H exhibits cytotoxicity against cancer cells and epithelial cells, and possesses antibacterial activity against Staphylococcus aureus, methicillin-resistant Staphylococcus aureus, and vancomycin-sensitive Enterococcus faecium. SB87-H can be used in studies related to bacteria infections.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 163768-82-9
分子式: C₂₀H₂₀O₆
分子量:356.37

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

SB87-H 構造式

CAS 番号: 163768-82-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

SB87-H (compound 9) (0.31-10 μg/mL; 6-8 h) inhibits the growth of Staphylococcus aureus, methicillin-resistant Staphylococcus aureus, and vancomycin-susceptible Enterococcus faecium with an MIC of 10 μg/mL, and shows no activity against vancomycin-resistant Enterococcus faecium^[1].
SB87-H (0.016-50 μM) potently induces cytotoxicity in A549, HeLa, HepG2, MCF-7, and Vero cells with IC₅₀ values ranging from 1.5-2.2 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 163768-82-9
分子量 356.37
分子式 C₂₀H₂₀O₆
SMILES

O=CC1=C(C=C(C(C/C=C(C)\C)=C1C(C2=C(C=C(C)C=C2O)O)=O)O)O
Structure Classification
- Phenols
- Polyphenols
Initial Source
- Microorganisms
Pestalotiopsis trachicarpicola SC-J551
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Jiang Z, et al. Pestalotinones A-D, new benzophenone antibiotics from endophytic fungus Pestalotiopsis trachicarpicola SC-J551. The Journal of antibiotics. 2022 Apr;75(4):207-212. [Content Brief]

[2]. Song F. Antimicrobial Natural Products. Antibiotics. 2022 Dec 7;11(12):1765.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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