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Cat. No.: HY-N8351

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Vobtusine

(Synonyms: NSC 180540; Vobtusin)

Vobtusine is an alkaloid that has been found in V. africana leaves.

For research use only. We do not sell to patients.

CAS No.: 19772-79-3
Formula: C₄₃H₅₀N₄O₆
Molecular Weight:718.88

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (278 KB)

Vobtusine Chemical Structure

CAS No.: 19772-79-3

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Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Vobtusine is an alkaloid that has been found in V. africana leaves.

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	>10 μM Compound: 14	Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 33112136]
HepG2	IC₅₀	>10 μM Compound: 14	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 33112136]
MDA-MB-231	IC₅₀	>10 μM Compound: 14	Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 33112136]
SK-MEL-28	IC₅₀	>10 μM Compound: 14	Cytotoxicity against human SK-MEL-28 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human SK-MEL-28 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 33112136]
SW480	IC₅₀	>10 μM Compound: 14	Cytotoxicity against human SW480 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human SW480 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 33112136]
T47D	IC₅₀	>10 μM Compound: 14	Cytotoxicity against human T47D cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human T47D cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 33112136]

Chemical Information

CAS No. 19772-79-3
Molecular Weight 718.88
Formula C₄₃H₅₀N₄O₆
SMILES

O[C@@]12[C@@](C3=CC=C4)(CCN5CC[C@]6([H])OCC7)[C@]5([H])[C@]67C[C@@]1([H])C[C@@]8([C@@](OCC9)([H])[C@@]9(CC(C(OC)=O)=C%10[C@@]%11(C%12=CC=CC=C%12N%10)CC%13)[C@]%11([H])N%13C8)CN2C3=C4OC
Synonyms

NSC 180540; Vobtusin
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (278 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Koroch, et al. Voacanga africana: Chemistry, quality and pharmacological activity. African Natural Plant Products: New Discoveries and Challenges in Chemistry and Quality 1021, 363-380 (2009).

Calculators

Molarity Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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