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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
197 Results for "
elastase
" in MedChemExpress (MCE) Product Catalog:
Products (197)
197 Results for "elastase" in MCE Product Catalog:
Cat. No.: HY-76705S
CAS No.: 2562378-12-3
Target:
Isotope-Labeled Compounds Bacterial DNA/RNA Synthesis Apoptosis Reactive Oxygen Species (ROS)
Research Areas:
Methyl N-methylanthranilate-d3 is the deuterated-labeled Methyl N-methylanthranilate (HY-76705). Methyl N-methylanthranilate is an N-alkylated anthranilate with a sweet citrus aroma, which is commonly used in perfume manufacturing. Methyl N-methylanthranilate is the dominant component in the defensive secretion of the millipede Typhloiulus orpheus. Methyl N-methylanthranilate exhibits quorum sensing inhibition and anti-biofilm activity against P. aeruginosa; it interferes with PQS synthesis via competitive inhibition of PqsA, but lacks bactericidal activity. Methyl N-methylanthranilate is sensitive to UVA/sunlight in human skin cells, and generates O2• - through type I photodynamic reactions, leading to lysosomal/mitochondrial damage, double-strand DNA breaks and apoptosis, with potential phototoxicity .
Cat. No.: HY-P7542
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SERPINA1; Serpin A1; Prev. PI; Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1, Isoform CRA_a; Alpha-1-Antitrypsin; Serine (Or Cysteine) Proteinase Inhibitor, Clade A, Member 1; AAT; Protease Inhibitor 1 (Anti-elastase)
Species:
Human
Source:
HEK293
Cat. No.: HY-P74556
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SERPINA1; Serpin A1; Prev. PI; Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1, Isoform CRA_a; Alpha-1-Antitrypsin; Serine (Or Cysteine) Proteinase Inhibitor, Clade A, Member 1; AAT; Protease Inhibitor 1 (Anti-elastase)
Species:
Rat
Source:
HEK293
Cat. No.: HY-P70316
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PI3; WAP Four-Disulfide Core Domain Protein 14; Peptidase Inhibitor 3; Peptidase Inhibitor 3, Skin-Derived; WFDC14; elastase-Specific Inhibitor; SKALP; Protease Inhibitor WAP3; WAP3; Trappin-2; ESI; PI-3; Skin-Derived Antileukoproteinase; WAP Four-Disulfi
Species:
Human
Source:
HEK293
Cat. No.: HY-P10143
CAS No.: 99828-55-4
Synonyms: Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt
Cat. No.: HY-P10868
CAS No.: 2056232-82-5
Synonyms: RLS-0071
Target:
Research Areas:
Cat. No.: HY-P72289
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SERPINB1; Epididymis Secretory Protein Li 27; Prev. ELANH2; Peptidase Inhibitor 2; MNEI; HEL-S-27; PI2; M/NEI; LEI; PI-2; EI; Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1, Isoform CRA_a; Leukocyte elastase Inhibitor; Protease Inhibitor 2 (Ant
Species:
Pig
Source:
E. coli
Cat. No.: HY-185463
CAS No.: 725228-46-6
Target:
Research Areas:
β-Tryptase-IN-1 is a selective β-tryptase inhibitor with a Ki of 10 nM. β-Tryptase-IN-1 binds to the inducible S4 + pocket unique to β-tryptase. β-Tryptase-IN-1 can be used for the researches of asthma and chronic obstructive pulmonary disease (COPD) .
Cat. No.: HY-P10868A
Synonyms: RLS-0071 TFA
Target:
Research Areas:
Cat. No.: HY-169323
CAS No.: 2921735-87-5
Synonyms: Mal-Exo-EEVC-MMAE
Target:
Research Areas:
APL-1091 (Mal-Exo-EEVC-MMAE) is an ADC payload-linker conjugate (Drug-Linker Conjugates for ADC). APL-1091 is formed by the conjugation of the Mal-Exo-EEVC (HY-169353) linker and MMAE (HY-15162), a microtubule inhibitor. APL-1091 resists aggregation at high drug-to-antibody ratio (DAR), exhibits excellent plasma stability, and reduces premature payload release. When conjugated with Trastuzumab (HY-P9907), APL-1091 displays anti-tumor activity in gastric cancer xenograft models. APL-1091 can be used for ADC synthesis and gastric cancer-related research .
Cat. No.: HY-N17997
CAS No.: 1924616-12-5
Target:
Cat. No.: HY-P72505A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MME; Neprilysin-390; Membrane Metalloendopeptidase; Neprilysin-411; Neprilysin; SFE; CALLA; Membrane Metallo-Endopeptidase (Neutral Endopeptidase, Enkephalinase, CALLA, CD10); NEP; Membrane Metallo-Endopeptidase Variant 2; Neutral Endopeptidase 24.11; Alternative Protein MME; Skin Fibroblast elastase; CD10 Antigen; Atriopeptidase; MME Protein; Enkephalinase; CMT2T; CD10; SCA43; Common Acute Lymphocytic Leukemia Antigen; EPN; Neutral Endopeptidase
Species:
Human
Source:
HEK293
Cat. No.: HY-183711
Target:
Research Areas:
Antibacterial agent 344 is an antibacterial agent with potent biofilm inhibition (IC50 = 0.27 μM). Antibacterial agent 344 inhibits heme oxygenase (HemO), impairs iron homeostasis, virulence factor production, and motility. Antibacterial agent 344 synergizes with Ciprofloxacin (HY-B0356) and Tobramycin (HY-B0441), enhancing their efficacy and delaying the development of resistance. Antibacterial agent 344 improves bacterial-infected Galleria mellonella survival, and reduces bacterial load in mice wounds. Antibacterial agent 344 can be used for the research of Pseudomonas aeruginosa infections .
Cat. No.: HY-P991998
Target:
Research Areas:
Cat. No.: HY-N13250
Cat. No.: HY-W788542
CAS No.: 205514-29-0
Quoromycin is an orally active SmcR inhibitor with a Kd of 0.697 μM for Vibrio vulnificus SmcR. Quoromycin binds directly to SmcR, reduces its DNA-binding affinity, and inhibits the quorum sensing signaling pathway. Quoromycin is applicable to the research of Vibrio vulnificus infection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
