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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2543 Results for "
Class
" in MedChemExpress (MCE) Product Catalog:
Products (2543)
2543 Results for "Class" in MCE Product Catalog:
Cat. No.: HY-P72710
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD74; Ia-Associated Invariant Chain; Prev. DHLAG; HLA-DR-Gamma; CLIP; Ia Antigen-Associated Invariant Chain; CD74 Antigen (Invariant Polypeptide Of Major Histocompatibility Complex, Class II Antigen-Associated); CD74 Antigen; CD74 Molecule, Major Histocom
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P73522
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FCGRT; Major Histocompatibility Complex Class I-Like Fc Receptor; Fc Gamma Receptor And Transporter; Neonatal Crystallizable Fc Receptor FcRn Splice Variant 6; Neonatal Fc Receptor; Neonatal Crystallizable Fc Receptor FcRn Splice Variant 5; FcRn; Neonatal
Species:
Human
Source:
HEK293
Cat. No.: HY-P73832
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: MAX; BHLHd5; MYC Associated Transcriptional Regulator X; BHLHd6; MYC Associated Factor X; BHLHd7; BHLHd4; BHLHd8; Protein Max; MAX Protein; Class D Basic Helix-Loop-Helix Protein 4; BHLHD4; Myc-Associated Factor X; PDMCS
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P76920
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FCGRT; Major Histocompatibility Complex Class I-Like Fc Receptor; Fc Gamma Receptor And Transporter; Neonatal Crystallizable Fc Receptor FcRn Splice Variant 6; Neonatal Fc Receptor; Neonatal Crystallizable Fc Receptor FcRn Splice Variant 5; FcRn; Neonatal
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P78262
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD74; Ia-Associated Invariant Chain; Prev. DHLAG; HLA-DR-Gamma; CLIP; Ia Antigen-Associated Invariant Chain; CD74 Antigen (Invariant Polypeptide Of Major Histocompatibility Complex, Class II Antigen-Associated); CD74 Antigen; CD74 Molecule, Major Histocom
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P700514
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: USF1; Upstream Transcription Factor 1; BHLHb11; Major Late Transcription Factor 1; Upstream Stimulatory Factor 1; MLTFI; UEF; Class B Basic Helix-Loop-Helix Protein 11; HYPLIP1; BHLHB11; FCHL1; FCHL; MLTF; USF
Species:
Human
Source:
E. coli
Cat. No.: HY-P75760A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FCGRT; Major Histocompatibility Complex Class I-Like Fc Receptor; Fc Gamma Receptor And Transporter; Neonatal Crystallizable Fc Receptor FcRn Splice Variant 6; Neonatal Fc Receptor; Neonatal Crystallizable Fc Receptor FcRn Splice Variant 5; FcRn; Neonatal
Species:
Rat
Source:
HEK293
Cat. No.: HY-P702776
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MYCN; Neuroblastoma MYC Oncogene; Prev. NMYC; Oncogene NMYC; BHLHe37; MYCNsORF; N-Myc; MYCNsPEP; V-Myc Avian Myelocytomatosis Viral Oncogene Neuroblastoma Derived Homolog; BHLHE37; Class E Basic Helix-Loop-Helix Protein 37; FGLDS1; N-Myc Proto-Oncogene Pr
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P703457
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: ADH1B; Alcohol Dehydrogenase 2 (Class I), Beta Polypeptide; Prev. ADH2; Aldehyde Reductase; All-Trans-Retinol Dehydrogenase [NAD(+)] ADH1B; ADH, Beta Subunit; Epididymis Secretory Protein Li 117; HEL-S-117; Alcohol Dehydrogenase Subunit Beta; Alcohol Dehy
Species:
Others
Source:
E. coli
Cat. No.: HY-P85195
Synonyms: HAND1; BHLHA27; EHAND; Heart- and neural crest derivatives-expressed protein 1; Class A basic helix-loop-helix protein 27; bHLHa27; Extraembryonic tissues; heart, autonomic nervous system and neural crest derivatives-expressed protein 1; eH
Cat. No.: HY-P705348
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HLAA; HLA-A; Human leukocyte antigen A; HLA Class I histocompatibility antigen, A alpha chain; HDCMA22P; CDABP0092; B2M; Beta-2-microglobulin form pI 5.3
Species:
Human
Source:
HEK293
Cat. No.: HY-124940
CAS No.: 446877-42-5
Target:
Research Areas:
CPU-228 is a complex class III antiarrhythmic agent. CPU-228 concentration-dependently blocks the activities of the rapid component 50 of the delayed rectifier potassium channel (IKr) and the L-type calcium channel (ICa,L), with an IC50 value of 0.909 μM for ICa,L current. CPU-228 produces negative inotropic effects and induces mild, non-frequency-dependent prolongation of the effective refractory period (ERP) in isolated left atria. CPU-228 reduces the incidence of torsades de pointes (TDP) in anesthetized rabbits and inhibits ischemia/reperfusion-induced arrhythmias in rats. CPU-228 can be used in studies related to torsades de pointes .
PI3K/mTOR Inhibitor-4 is an orally active pan-class I PI3K/mTOR inhibitor. PI3K/mTOR Inhibitor-4 has enzymatic inhibition activity for PI3Kα, PI3Kγ, PI3Kδ and mTOR with IC50 values of 0.63 nM, 22 nM, 9.2 nM and 13.85 nM, respectively. PI3K/mTOR Inhibitor-4 can be used for the research of cancer .
Cat. No.: HY-133794R
CAS No.: 910297-52-8
Target:
Research Areas:
L-Ascorbic acid (GMP Like) (Standard) is the analytical standard of L-Ascorbic acid (GMP Like). This product is intended for research and analytical applications. L-Ascorbic acid (GMP Like) is the GMP Like class L-Ascorbic acid (HY-B0166). L-Ascorbic acid (L-Ascorbate, Vitamin C), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
Synonyms: Q702
Target:
Research Areas:
Adrixetinib (Q702) is an orally active triple inhibitor against CSF1R, Mer, and Axl, with Kd values of 8.7 nM, 0.8 nM, and 0.3 nM, respectively. Adrixetinib acts as a potent immune modulator that remodels the tumor microenvironment. Adrixetinib increases the abundance of M1 macrophages and CD8⁺ T cells, while decreasing the levels of M2 macrophages and myeloid-derived suppressor cells (MDSCs). Adrixetinib upregulates the expression of MHC class I and E-cadherin in tumor cells. Adrixetinib shows remarkable antitumor efficacy in syngeneic mouse tumor models. Adrixetinib is suitable for the research of breast cancer, renal adenocarcinoma, colon carcinoma, and melanoma .
Cat. No.: HY-15900R
CAS No.: 934493-76-2
Synonyms: XL765 (Standard); SAR245409 (Standard)
Target:
Research Areas:
Voxtalisib (Standard) is the analytical standard of Voxtalisib. This product is intended for research and analytical applications. Voxtalisib (XL765) is a potent PI3K inhibitor, which has a similar activity toward class I PI3K (IC50s=39, 113, 9 and 43 nM for p110α, p110β, p110γ and p110δ, respectively), also inhibits DNA-PK (IC50=150 nM) and mTOR (IC50=157 nM). Voxtalisib (XL765) inhibits mTORC1 and mTORC2 with IC50s of 160 and 910 nM, respectively.
Cat. No.: HY-164202
Research Areas:
ORM-5029 is a first-in-class human epidermal growth factor receptor 2 (HER2)-targeted antibody-drug conjugate (ADC) comprised of SMol006, a highly potent GSPT1 degrader, conjugated to Pertuzumab (HY-P9912). ORM-5029 exhibits robust efficacy across 14 HER2-positive breast cancer cell lines, with IC50 values ranging from 0.3 to 14.4 nM.ORM-5029 demonstrates anti-tumor activity in the BT474 xenograft model. ORM-5029 can be used for study of breast cancer .
Cat. No.: HY-171754
Target:
Research Areas:
LM-305 is an anti-G protein-coupled receptor class 5 member D (GPRC5D) antibody-drug conjugate (ADC). LM-305 consists of Anti-GPRC5D Antibody (HY-P991197) and VcMMAE (HY-15575). LM-305 exhibits potent cytotoxicity against multiple myeloma cells (NCI-H929 and MM.1R) with IC50 values ranging from 0.1 to 0.3 nM. LM-305 can be used in the study of GPRC5D-related relapsed and refractory multiple myeloma (RRMM) .
Cat. No.: HY-186105
CAS No.: 1421622-85-6
Target:
Research Areas:
P7C3-S243 is a brain-penetrant P7C3 class of neuroprotective agent. P7C3-S243 augments synthesis of nicotinamide adenine dinucleotide through activation of the metabolic enzyme nicotinamide phosphoribosyltransferase. P7C3-S243 shows potent neuroprotective efficacy in parkinson’s disease mice models. P7C3-S243 can be used for the research of parkinson’s disease .
Cat. No.: HY-E70529
Target:
Research Areas:
Ribonucleoside vanadyl complexes are a class of potent RNase and Taq polymerase inhibitors. Ribonucleoside vanadyl complexes protect RNA during RNA isolation by inhibiting ribonucleases, and also reduce the viability of bacteria and eukaryotic cells by interfering with ribosomal subunit assembly. Ribonucleoside vanadyl complexes block PCR and reverse transcription reactions templated by viral nucleic acids and enhance the effects of antibiotics against Staphylococcus aureus, but do not directly inhibit protein synthesis. Ribonucleoside vanadyl complexes can be effectively removed by phenol-chloroform extraction, thus enabling subsequent PCR analysis. Ribonucleoside vanadyl complexes can be applied in research related to chronic hepatitis C (HCV) and Staphylococcus aureus infection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
