273 Results for "

5R

" in MedChemExpress (MCE) Product Catalog:
Products (273)

273 Results for "5R" in MCE Product Catalog:

Cat. No.: HY-44323
CAS No.: 13639-50-4
Synonyms: (2R,3R,4S,5R,6S)-2-(Acetoxymethyl)-6-(acetylthio)tetrahydro-2H-pyran-3,4,5-triyl triacetate
Target:  

Drug Intermediate

Research Areas:  

Others

2,3,4,6-Tetra-O-acetyl-1-S-acetyl-1-thiohexopyranose ((2R,3R,4S,5R,6S)-2-(Acetoxymethyl)-6-(acetylthio)tetrahydro-2H-pyran-3,4,5-triyl triacetate) is a drug intermediate for synthesis of various active compounds.
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Cat. No.: HY-148109
CAS No.: 19948-85-7
Purity:  98.55%
Target:  

FAK

Research Areas:  

Cancer

FAK-IN-7 (compound 5r) is a FAK inhibitor (IC50=11.72 µM). FAK-IN-7 has good anti-proliferative activity and can be used in cancer research .
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Cat. No.: HY-I0622
CAS No.: 863329-65-1
Synonyms: ((2R,3R,4R,5R)-3-(benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-4-methyltetrahydrofuran-2-yl)methyl benzoate
Target:  

Drug Intermediate

Research Areas:  

Others

3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-2'-methyluridine (((2R,3R,4R,5R)-3-(benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-4-methyltetrahydrofuran-2-yl)methyl benzoate) is a drug intermediate for synthesis of various active compounds.
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Cat. No.: HY-W048220
CAS No.: 90989-12-1
Research Areas:  

Infection

(S)-2-Aminohex-5-enoic acid is an enantiomerically pure non-proteinogenic α-amino acid (homoallylglycine) and synthetic precursor for (2S,5R)- and (2S,5S)-5-hydroxypipecolic acid. (S)-2-Aminohex-5-enoic acid can be used in research on bacterial and fungal infections .
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Cat. No.: HY-109022A
Purity:  99.55%
Synonyms: (3R,5R,6S)-MK-8031; (3R,5R,6S)-AGN-241689
Target:  

CGRP Receptor

Research Areas:  

Neurological Disease

(3R,5R,6S)-Atogepant ((3R,5R,6S)-MK-8031) is the enantiomer of Atogepant (HY-109022). Atogepant is a calcitonin gene-related peptide receptor (CGRP) antagonist. Atogepant can be used for researching migraine.
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Cat. No.: HY-14664C
CAS No.: 94061-81-1
Purity:  98.16%
Synonyms: (3S,5R)-XU 62-320
Research Areas:  

Cardiovascular Disease Cancer

(3S,5R)-Fluvastatin sodium ((3S,5R)-XU 62-320) is the (3S,5R)-enantiomer of Fluvastatin. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .
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Cat. No.: HY-128837A
CAS No.: 2760669-71-2
(4S,5R)-Nutlin carboxylic acid is the Nutlin 3-based MDM2 ligand. (4S,5R)-Nutlin carboxylic acid can be connected to the ligand for protein by a linker to form PROTAC .
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Cat. No.: HY-17504C
CAS No.: 1094100-06-7
(3R,5R)-Rosuvastatin is a hERG potassium channel blocker and HMG-CoA reductase inhibitor that prolongs the action potential duration and QT interval by accelerating channel inactivation, impairing channel folding, reducing hERG mRNA transcription, and promoting the degradation of mature and immature hERG channels. (3R,5R)-Rosuvastatin can be used for research on long QT syndrome .
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Cat. No.: HY-14664CS
CAS No.: 2249799-35-5
Purity:  ≥98.0%
Synonyms: (3S,5R)-XU 62-320-d6
(3S,5R)-Fluvastatin-d6 (sodium)?is the deuterium labeled (3S,5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic, competitive?HMG-CoA reductase?inhibitor with an IC50?of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway .
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Cat. No.: HY-17504D
CAS No.: 1242184-42-4
(3S,5R)-Rosuvastatin is the (3S,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM . Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC50 of 195 nM . Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin is very effective in lowering low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels .
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Cat. No.: HY-19654B
CAS No.: 863680-46-0
Synonyms: (1S,5R)-GSK598809
Target:  

Dopamine Receptor

Research Areas:  

Others

(-)-GSK598809 ((1S,5R)-GSK598809) is an isomer of GSK598809. GSK598809 is a potent and selective dopamine D3 Receptor (DRD3) antagonist.
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Cat. No.: HY-19282A
CAS No.: 189013-61-4
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

(5R)-BW-4030W92 is the R enantiomer of BW-4030W92. BW-4030W92 is a non-selective, voltage-, and use-dependent sodium channel antagonist.
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Cat. No.: HY-I0896
CAS No.: 149809-43-8
Target:  

Drug Intermediate

Research Areas:  

Others

P-Toluenesulfonic Acid (3S,5R)-5-(2,4-Difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-ylmethyl Ester is a drug intermediate for synthesis of various active compounds.
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Cat. No.: HY-23154
CAS No.: 51549-32-7
Target:  

Drug Intermediate

Research Areas:  

Others

9-((2R,4S,5R)-4-((tert-Butyldimethylsilyl)oxy)-5-(((tert-butyldimethylsilyl)oxy)methyl)tetrahydrofuran-2-yl)-9H-purin-6-amine is a drug intermediate for synthesis of various active compounds.
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Cat. No.: HY-W011090S
Synonyms: CMP-13C9,15N3
((2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate- 13C9, 15N3 (sodium) is the 13C and 15N labeled Sodium ((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate .
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Cat. No.: HY-W076424R
CAS No.: 1009092-91-4
Target:  

Reference Standards

tert-Butyl (4R,5R)-4-(hydroxymethyl)-2,2-dimethyl-5-phenyloxazolidine-3-carboxylate (Standard) is the analytical standard of tert-Butyl (4R,5R)-4-(hydroxymethyl)-2,2-dimethyl-5-phenyloxazolidine-3-carboxylate. This product is intended for research and analytical applications.
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Cat. No.: HY-N16604
CAS No.: 120850-08-0
(+)-3β-Hydroxycarvotagenone (Compound (4S,5R)-(−)-6a) is a α-phellandrene (HY-121615) derivative .
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Cat. No.: HY-Z10518
CAS No.: 1422515-55-6
Research Areas:  

Cardiovascular Disease

((3R,5R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate) calcium(II) is an impurity found in bulk preparations of the HMG-CoA reductase inhibitor Rosuvastatin (HY-17504A).
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Cat. No.: HY-138879B
CAS No.: 357425-68-4
Purity:  99.74%
Synonyms: (1S,5R)-CP-601927
Target:  

nAChR

Research Areas:  

Neurological Disease

CP-601932 ((1S,5R)-CP-601927) is a high-affinity partial agonist at α3β4 nAChR (Ki=21 nM; EC50=~ 3 μM). CP-601932 has the same high-binding affinity at α4β2 nAChR (Ki=21 nM) and an order of magnitude lower affinity for α6 and α7 nAChR subtypes. CP-601932 selectively decreases ethanol but not sucrose consumption and operant self-administration following long-term exposure. CP-601932 can penetrate the CNS .
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Cat. No.: HY-155502
CAS No.: 3028287-43-3
Research Areas:  

Cancer

AKR1C3-IN-10 (compound 5r) is a selective AKR1C3 inhibitor (IC50=51 nM). AKR1C3-IN-10 shows good activity in a prostate cancer xenograft model .
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