FAK-IN-7
Based on 1 Customer Validation
FAK-IN-7 (compound 5r) is a FAK inhibitor (IC50=11.72 µM). FAK-IN-7 has good anti-proliferative activity and can be used in cancer research.
For research use only. We do not sell to patients.
- Purity: 98.55%
- CAS No.: 19948-85-7
- Formula: C16H13N3OS
- Molecular Weight:295.36
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
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Bioactive Compound Library
HY-L001
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Kinase Inhibitor Library
HY-L009
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Protein Tyrosine Kinase Compound Library
HY-L016
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Anti-Cancer Compound Library
HY-L025
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Cytoskeleton Compound Library
HY-L060
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Anti-Pancreatic Cancer Compound Library
HY-L077
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Anti-Pulmonary Fibrosis Compound Library
HY-L125
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MCE Bioactive Compound Library
HY-L001V
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Protein Kinase Compound Library
HY-L196
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High-Throughput Bioactive Compound Library
HY-L205
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Posttranslational Modification Library
HY-L226
Biological Activity
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FAK 11.72 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
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| B16-F10 | IC50 |
3.52 μM
Compound: 5r
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Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT assay
Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT assay
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[PMID: 22503364] |
| MCF7 | IC50 |
3.57 μM
Compound: 5r
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Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
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[PMID: 22503364] |
FAK-IN-7 (0-10 µM; 48 h) inhibits MCF-7 and B16-F10 cells proliferation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:MCF-7 and B16-F10 cells
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Concentration:0-10 µM
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Incubation Time:48 h
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Result:Exhibited anti-proliferative activity against MCF-7 and B16-F10 cells with IC50 values of 3.57 and 3.52 µM, respectively.
Chemical Information
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CAS No. 19948-85-7
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Appearance Solid
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Molecular Weight 295.36
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Formula C16H13N3OS
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Color White to off-white
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SMILES
O=C(NC1=NN=C(C2=CC=C(C)C=C2)S1)C3=CC=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 10 mg/mL (33.86 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3857 mL | 16.9285 mL | 33.8570 mL | 84.6425 mL |
| 5 mM | 0.6771 mL | 3.3857 mL | 6.7714 mL | 16.9285 mL | |
| 10 mM | 0.3386 mL | 1.6928 mL | 3.3857 mL | 8.4642 mL | |
| 15 mM | 0.2257 mL | 1.1286 mL | 2.2571 mL | 5.6428 mL | |
| 20 mM | 0.1693 mL | 0.8464 mL | 1.6928 mL | 4.2321 mL | |
| 25 mM | 0.1354 mL | 0.6771 mL | 1.3543 mL | 3.3857 mL | |
| 30 mM | 0.1129 mL | 0.5643 mL | 1.1286 mL | 2.8214 mL |
FAK-IN-7 Related Classifications
HY-148109 Related Classifications
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