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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
29 Results for "
ACAT-1
" in MedChemExpress (MCE) Product Catalog:
Products (29)
29 Results for "ACAT-1" in MCE Product Catalog:
Cat. No.: HY-P78986A
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACAT1; Acetyl-Coenzyme A Acetyltransferase 1; Prev. ACAT; MAT; Acetyl-CoA Acetyltransferase, Mitochondrial; T2; Acetoacetyl-CoA Thiolase; Mitochondrial Acetoacetyl-CoA Thiolase; THIL; Testicular Tissue Protein Li 198; Acetyl-CoA Acetyltransferase 1; Aceto
Species:
Human
Source:
E. coli
Target:
Research Areas:
LDL-IN-1 (Compound 1) is an antioxidant, and is active against copper mediated LDL oxidation (IC50 = 52 μM). LDL-IN-1 is also an Acyl-CoA:cholesterol acyltransferase-1 and -2 (ACAT-1/2) inhibitor, with IC50s of 60 μM. LDL-IN-1 can be used for anti-atherosclerotic research [1].
Cat. No.: HY-P82226A
Synonyms: T2; MAT; ACAT; THIL
Cat. No.: HY-13215A
CAS No.: 166518-61-2
Synonyms: CI-1011 sodium; PD-148515 sodium
Target:
Research Areas:
Avasimibe sodium (CI-1011 sodium; PD-148515 sodium) is an orally active acyl coenzyme A-cholesterol acyltransferase (ACAT; also called SOAT)) inhibitor with IC50s of 24 and 9.2 µM for ACAT1 and ACAT2, respectively [1]. Avasimibe sodium can be used for the research of prostate cancer .
Cat. No.: HY-N18066
CAS No.: 854381-37-6
Cat. No.: HY-100401AR
CAS No.: 608510-47-0
Synonyms: CS-505 (Standard)
Target:
Research Areas:
Pactimibe (sulfate) (Standard) is the analytical standard of Pactimibe (sulfate) (HY-100401A). This product is intended for research and analytical applications. Pactimibe sulfate (CS-505) is a dual ACAT1/2 inhibitor with IC50s of 4.9 μM and 3.0 μM, respectively. Pactimibe sulfate (CS-505) inhibits ACAT with IC50s of 2.0 μM, 2.7 μM, 4.7 μM in the liver, macrophages and THP-1 cells, respectively [1]. Pactimibe sulfate (CS-505) noncompetitively inhibits oleoyl-CoA with a Ki value of 5.6 μM. Moreover, Pactimibe sulfate (CS-505) obviously inhibits cholesteryl ester formation with an IC50 of 6.7 μM. Pactimibe sulfate (CS-505) possesses anti-atherosclerotic potential with lowering plasma cholesterol activity .
Cat. No.: HY-RS18683
Target:
Research Areas:
Soat1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Soat1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
