Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
107 Results for "
DOPA
" in MedChemExpress (MCE) Product Catalog:
Products (107)
107 Results for "DOPA" in MCE Product Catalog:
Target:
Research Areas:
6-Hydroxy-DOPA is a selective and effective allosteric inhibitor of the RAD52 ssDNA binding domain. 6-Hydroxy-DOPA can be used for the research of cancer .
Target:
Synonyms: RX 781094 hydrochloride
Research Areas:
Idazoxan hydrochloride (RX 781094 hydrochloride) is an α2-adrenoceptor antagonist and is also a imidazoline receptors (IRs) antagonist competitively antagonized the centrally induced hypotensive effect of imidazoline-like agents (IMs). Idazoxan hydrochloride also improves motor symptoms in Parkinson’s disease, L-DOPA-induced dyskinesias, and experimental Parkinsonism .
Category:
Natural Products Plants Moraceae Endogenous metabolite Human Gut Microbiota Metabolites Ficus carica L. Other Diseases Phenols Polyphenols Disease Research Fields
Target:
Category:
Monophenols Ketones, Aldehydes, Acids Phenols Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
Synonyms: 6-Nitroveratraldehyde
Target:
Research Areas:
DMNB (6-Nitroveratraldehyde) is a photolabile proton donor that releases acidic substances when excited at a wavelength of 405 nM. DMNB can be used for the synthesis of no-carrier-added 6-[18F]fluoro-L-DOPA (6-FDOPA). DMNB is also applicable to the preparation of o-nitroaryl-bis (5-methylfur-2-yl) methanes and the synthesis of alpha-asarone (HY-N0700). DMNB is an enzyme involved in the non-homologous end joining (NHEJ) pathway responsible for DNA double-strand break (DSB) repair. DMNB can be used in PET studies of the dopaminergic system .
Category:
Alkaloids Piperidine Alkaloids Ranunculaceae Other Diseases Plants Disease Research Fields
Target:
Cat. No.: HY-N0304S
CAS No.: 713140-75-1
Synonyms: LevoDOPA-d6; 3,4-Dihydroxyphenylalanine-d6
Synonyms: L-DOPA ethyl ester; LevoDOPA ethyl ester
Target:
Research Areas:
Etilevodopa (L-Dopa ethyl ester), an ethyl-ester proagent of Levodopa, is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. Etilevodopa is used for the treatment of Parkinson disease (PD). Levodopa is the direct precursor of dopamine and is a suitable proagent as it facilitates CNS penetration and delivers dopamine .
Synonyms: 3-Methoxy-L-tyrosine-d3; 3-O-Methyl-L-DOPA-d3
Synonyms: ABBV-951; CarbiDOPA 4′-monophosphate
Research Areas:
Foscarbidopa (ABBV-951; Carbidopa 4′-monophosphate) is an inhibitory prodrug targeting peripheral aromatic L-amino acid decarboxylase. Foscarbidopa is hydrolyzed into Carbidopa (HY-B0311) by phosphatases in vivo to suppress peripheral metabolism of levodopa and elevate brain delivery of levodopa. Foscarbidopa can be used for the research of Parkinson’s disease and advanced Parkinson’s disease .
Synonyms: BIA 3-202
Target:
Research Areas:
Nebicapone (BIA 3-202), a reversible catechol-O-methyltransferase (COMT) inhibitor, is mainly metabolized by glucuronidation. Nebicapone is mainly peripherally acting inhibitor that decreases the biotransformation of L-DOPA to 3-O-methyl-DOPA by inhibition of COMT, and it is potential for the treatment of Parkinson's disease .
Cat. No.: HY-141647
CAS No.: 1614253-58-5
Target:
Research Areas:
18F-Labeled L-dopa precursor is a precursor for synthesis of 18F-labeled L-dopa .
Target:
Research Areas:
LY 165163 is a potent 5-HT presynaptic receptor agonist. LY 165163 significantly decreases 5-HTP accumulation and increases DOPA accumulation in the cortex and striatum .
Cat. No.: HY-W037976
CAS No.: 25369-78-2
Synonyms: 5-Chloro-2-mercaptobenzimidazole
Research Areas:
Tyrosinase-IN-22 (compound 4) is an inhibitor of tyrosinase substrates (L-tyrosine and L-dopa) with IC50s of 60 nM and 30 nM, respectively. Tyrosinase-IN-22 also shows potent antioxidant and anti-melanogenic properties, thus can be used for relevant researches .
Cat. No.: HY-W152604
CAS No.: 5845-67-0
Synonyms: Cyclo(leu-gly)
Target:
Research Areas:
Cat. No.: HY-113468R
CAS No.: 7636-26-2
Synonyms: 3-Methoxytyrosine (Standard)
Category:
Cat. No.: HY-N0304S1
CAS No.: 201417-12-1
Synonyms: LevoDOPA-13C6; 3,4-Dihydroxyphenylalanine-13C6
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
