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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
29 Results for "
Dcn
" in MedChemExpress (MCE) Product Catalog:
Products (29)
29 Results for "Dcn" in MCE Product Catalog:
Cat. No.: HY-126075
CAS No.: 2247543-65-1
Target:
Research Areas:
WS-383 free base is a potent, selective and reversible inhibitor of DCN1-UBC12 interaction, with an IC50 of 11 nM. WS-383 free base inhibits Cul3/1 neddylation, induces accumulation of p21, p27 and NRF2 .
Cat. No.: HY-184536
CAS No.: 3085130-99-7
Target:
Research Areas:
DCN1 modulator-1 is a DCN1 modulator. DCN1 modulator-1 binds covalently to DCN2. DCN1 modulator-1 induces the expression of fetal hemoglobin mRNA (HBG1) and fetal hemoglobin protein (HbF). DCN1 modulator-1 is applicable to research related to sickle cell disease and thalassemia .
Cat. No.: HY-RS17215
Target:
Research Areas:
Dcn Mouse Pre-designed siRNA Set A contains three designed siRNAs for Dcn gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P704181
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Dcn; Decorin Proteoglycan; Decorin; Decorin Isoform 3; SLRR1B; Decorin Isoform 4; Bone Proteoglycan II; DKFZp686J19238; DSPG2; PG-S2; PG40; CSCD; Dermatan Sulphate Proteoglycans II; PGII; Small Leucine-Rich Protein 1B; PGS2; Proteoglycan Core Protein
Species:
Bovine
Source:
E. coli
Cat. No.: HY-P70021
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Dcn; Decorin Proteoglycan; Decorin; Decorin Isoform 3; SLRR1B; Decorin Isoform 4; Bone Proteoglycan II; DKFZp686J19238; DSPG2; PG-S2; PG40; CSCD; Dermatan Sulphate Proteoglycans II; PGII; Small Leucine-Rich Protein 1B; PGS2; Proteoglycan Core Protein
Species:
Mouse
Source:
HEK293
Cat. No.: HY-111505R
CAS No.: 2089293-61-6
Research Areas:
NAcM-OPT (Standard) is the analytical standard of NAcM-OPT (HY-111505). This product is intended for research and analytical applications. NAcM-OPT is an orally bioavailable cullin neddylation 1 (DCN1) inhibitor, which potently inhibits the DCN1-UBE2M interaction .
Cat. No.: HY-189074
Research Areas:
JN210 is a dual inhibitor of DCN1 and HDAC, with an IC50 of 94.26 nM against human DCN1. JN210 disrupts the UBE2M-DCN1 protein-protein interaction, blocks the neddylation modification of cullin-RING ligases, inhibits HDAC activity and induces histone hyperacetylation. JN210 impairs DNA damage repair function, induces cell apoptosis, exerts cytotoxicity and inhibits tumor growth. JN210 can be used for the research of non-small cell lung cancer .
Cat. No.: HY-P70093
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DCUN1D1; Dcn1-Like Protein 1; Defective In Cullin Neddylation 1 Domain Containing 1; DcnL1; DCUN1L1; Dcn1, Defective In Cullin Neddylation 1, Domain Containing 1 (S. Cerevisiae); SCCRO; Dcn1, Defective In Cullin Neddylation 1, Domain Containing 1; RP42; D
Species:
Human
Source:
E. coli
Cat. No.: HY-P76866
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DCUN1D2; DcnL2; Prev. C13orf17; Dcn1, Defective In Cullin Neddylation 1, Domain Containing 2; Defective In Cullin Neddylation Protein 1-Like Protein 2; Defective In Cullin Neddylation Protein 1-Like Protein; DCUN1 Domain-Containing Protein 2; Chromosome 1
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
