147 Results for "

FGFR3

" in MedChemExpress (MCE) Product Catalog:
Products (147)

147 Results for "FGFR3" in MCE Product Catalog:

Cat. No.: HY-18602
CAS No.: 1633044-56-0
Target:  

FGFR

Research Areas:  

Cancer

FIIN-2 is an irreversible inhibitor of FGFR with an IC50 of 3.1, 4.3, 27, and 45 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively.
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Cat. No.: HY-RS04919
Research Areas:  

Others

Fgfr3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fgfr3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P3695
CAS No.: 1206896-24-3
Target:  

FGFR

Research Areas:  

Cancer

VSPPLTLGQLLS is a small peptide FGFR3 inhibitor, peptide P3, inhibits FGFR3 phosphorylation. VSPPLTLGQLLS inhibits 9-cisRA-induced tracheal lymphangiogenesis and blocks lymphatic endothelial cell (LEC) proliferation, migration, and tubule formation .
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Cat. No.: HY-P991106
Synonyms: LY-3076226 antibody

Target:  

FGFR ADC Antibodies

Research Areas:  

Cancer

IMC-D11 (LY-3076226 antibody) is an anti-FGFR3 IgG1 monoclonal antibody with an EC50 of approximately 0.1 nM against hFGFR3b and hFGFR3c. IMC-D11 inhibits the growth of FGFR3-dependent lung adenocarcinoma in mouse models and shows no effect on tumors that do not express FGFR3. IMC-D11 can serve as an ADC Antibody for ADC synthesis, such as LY3076226. IMC-D11 is applicable to research related to urothelial carcinoma, multiple myeloma, lung adenocarcinoma, as well as advanced or metastatic cancers [3].
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Cat. No.: HY-RS04920
Research Areas:  

Others

Fgfr3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fgfr3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS04918
Research Areas:  

Others

FGFR3 Human Pre-designed siRNA Set A contains three designed siRNAs for FGFR3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-145231
CAS No.: 2677709-81-6
Purity:  98.25%
Target:  

FGFR

Research Areas:  

Cancer

FGFR2-IN-2 (Compound 38) is a selective FGFR2 inhibitor with IC50s of 389, 29, and 758 nM for FGFR1, FGFR2, and FGFR3, respectively .
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Cat. No.: HY-145895
CAS No.: 2906151-68-4
Purity:  99.58%
Target:  

FGFR SNIPERs

Research Areas:  

Cancer

SNIPER(TACC3)-11 is a potent FGFR3-TACC3 degrader. SNIPER(TACC3)-11 reduces FGFR3-TACC3 protein levels and suppressed the growth of FGFR3-TACC3 positive cancer cells .
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Cat. No.: HY-18603
CAS No.: 1637735-84-2
Target:  

EGFR FGFR

Research Areas:  

Cancer

FIIN-3 is an irreversible inhibitor of FGFR with an IC50 of 13.1, 21, 31.4, and 35.3 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively.
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Cat. No.: HY-P99823
CAS No.: 2226238-09-9
Synonyms: TA-46; sFGFR3

Target:  

FGFR

Research Areas:  

Others

Recifercept (TA-46) is a soluble, recombinant fibroblast growth factor receptor 3 (FGFR3) molecule. Recifercept can be used as a decoy/ligand trap to decrease the amount of fibroblast growth factors that can bind to mutant FGFR3 receptors. Recifercept can be used for the research of achondroplasia .
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Cat. No.: HY-E70720
Target:  

FGFR

Research Areas:  

Cancer

FGFR3 activating mutations are drivers of malignancy in several human tissues, including bladder, lung, cervix, and blood. FGFR3 K650M is a mutant of FGFR3. FGFR3 K650M Recombinant Human Active Protein Kinase is a recombinant FGFR3 K650M protein that can be used to study FGFR3 K650M-related functions .
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Cat. No.: HY-E70828
Target:  

FGFR

Research Areas:  

Cancer

FGFR3 kinase mutations are associated with a variety of malignancies. FGFR3 V555L mutation leads to resistance to FGFR inhibitors. FGFR3 V555L Recombinant Human Active Protein Kinase is a recombinant FGFR3 V555L protein that can be used to study FGFR3 V555L-related functions .
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Cat. No.: HY-E70719
Target:  

FGFR

Research Areas:  

Cancer

FGFR3 activating mutations are drivers of malignancy in several human tissues, including bladder, lung, cervix, and blood. FGFR3 K650E is a mutant of FGFR3 that may be present in multiple myeloma cell lines. FGFR3 K650E Recombinant Human Active Protein Kinase is a recombinant FGFR3 K650E protein that can be used to study FGFR3 K650E-related functions .
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Cat. No.: HY-E70829
Target:  

FGFR

Research Areas:  

Cancer

FGFR3 kinase mutations are associated with a variety of malignancies. FGFR3 V555M mutation leads to resistance to FGFR inhibitors. FGFR3 V555M Recombinant Human Active Protein Kinase is a recombinant FGFR3 V555M protein that can be used to study FGFR3 V555M-related functions .
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Cat. No.: HY-148778
CAS No.: 2833706-13-9
Target:  

FGFR

Research Areas:  

Cancer

FGFR3-IN-4 is a selective FGFR3 inhibitor, with an IC50 value of less than 50 nM. FGFR3-IN-4 is at least 10 fold more selective for FGFR3 than for FGFR1 .
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Cat. No.: HY-147714
CAS No.: 2428742-58-7
Target:  

FGFR VEGFR

Research Areas:  

Cancer

FGFR3-IN-2 (compound 18b) is a potent and selective FGFR3 inhibitor, with IC50s of 4.1 nM and 570 nM for FGFR3 and VEGFR2, respectively. FGFR3-IN-2 can be used for the research of bladder cancer .
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Cat. No.: HY-156790
CAS No.: 2833703-72-1
Target:  

FGFR

Research Areas:  

Cancer

FGFR3-IN-6 is a potent and selective FGFR3 inhibitor with IC50 value less than 350 nM. FGFR3-IN-6 can be used in research of cancer .
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Cat. No.: HY-158011
CAS No.: 2446523-17-5
Target:  

FGFR

Research Areas:  

Cancer

FGFR3-IN-9 (example27) is a selective FGFR3 inhibitor .
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Cat. No.: HY-151903S
CAS No.: 2640352-86-7
FGFR2/3-IN-1 is a potent and selective FGFR2 and FGFR3 (FGFR) inhibitor with IC50s of 1 nM and 0.5 nM, respectively. FGFR2/3-IN-1 displays >40-fold selectivity over FGFR1/FGFR4 and other kinome. FGFR2/3-IN-1 also inhibits FGFR3 V555L and V555M mutants with IC50s of 2.7 nM and 6.1 nM, respectively .
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