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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
37 Results for "
MCT-1
" in MedChemExpress (MCE) Product Catalog:
Products (37)
37 Results for "MCT-1" in MCE Product Catalog:
Cat. No.: HY-119996
CAS No.: 873327-59-4
Research Areas:
AR-C141990 (Compound 30) is a potent blocker of the monocarboxylate transporter MCT1 with a Ki of 4.8 nM. AR-C141990 (Compound 30) inhibits CYP3A4 and CYP2C9 with IC50 values of 16 μM [1].
Cat. No.: HY-P10561
Target:
Research Areas:
Cat. No.: HY-114602
CAS No.: 216685-07-3
Target:
Research Areas:
AR-C117977 is a potent monocarboxylate transporter (MCT1) inhibitor. AR-C117977 prolongs the survival of skin and heart sllograft. AR-C117977 inhibits the development of transplant arteriosclerosis in aortic allografts partially, but was unable to inhibit alloantibody production after transplantation. AR-C117977 shows potent immunosuppressive properties in vivo effectively preventing acute but not chronic allograft rejection in the mouse [1].
Cat. No.: HY-P83499A
Synonyms: HHF7; MCT 1; MCT; Slc16a1
Cat. No.: HY-RS13017
Target:
Research Areas:
Slc16a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc16a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02853
Target:
Research Areas:
CMA1 Human Pre-designed siRNA Set A contains three designed siRNAs for CMA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS13018
Target:
Research Areas:
Slc16a1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc16a1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08216
Target:
Research Areas:
MCAT Human Pre-designed siRNA Set A contains three designed siRNAs for MCAT gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-B1804S1
Synonyms: Trioctanoin-d50; Glyceryl trioctanoate-d50
Cat. No.: HY-B1804S2
CAS No.: 352431-24-4
Synonyms: Trioctanoin-d15; Glyceryl trioctanoate-d15
Cat. No.: HY-12750R
CAS No.: 1448671-31-5
Research Areas:
AZD3965 (Standard) is the analytical standard of AZD3965 (HY-12750). This product is intended for research and analytical applications. AZD3965 is a selective MCT1 inhibitor with a Ki of 1.6 nM, showing 6-fold selectivity over MCT2.
Cat. No.: HY-P74252
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CMA1; Chymase; Chymase 1; CYH; Chymase 1 Preproprotein Transcript E; Chymase, Mast Cell; Chymase 1 Preproprotein Transcript I; Chymase, Heart; Chymase 1, Mast Cell; MCT1; Mast Cell Protease I; CYM; Alpha-Chymase
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P72290
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CMA1; Chymase; Chymase 1; CYH; Chymase 1 Preproprotein Transcript E; Chymase, Mast Cell; Chymase 1 Preproprotein Transcript I; Chymase, Heart; Chymase 1, Mast Cell; MCT1; Mast Cell Protease I; CYM; Alpha-Chymase
Species:
Mouse
Source:
E. coli
Cat. No.: HY-184926
Target:
LYTACs Asialoglycoprotein Receptor (ASGPR) Monocarboxylate Transporter Mitochondrial Metabolism MMP Cadherin
Research Areas:
PEG9MA10-PAB10-GalMA10 is a CD147 LYTAC degrader. PEG9MA10-PAB10-GalMA10 binds to the asialoglycoprotein receptor (ASGPR) via its galactose methacrylate domain, mediating its uptake by hepatoma cells. PEG9MA10-PAB10-GalMA10 induces lysosome-dependent degradation of CD147, resulting in concurrent loss of associated MCT1 and MCT4. PEG9MA10-PAB10-GalMA10 reduces extracellular lactate levels, increases intracellular lactate accumulation, inhibits glycolytic activity, and enhances mitochondrial respiratory capacity. PEG9MA10-PAB10-GalMA10 decreases the secretion of MMP-2 and MMP-9, and upregulates the expression of E-cadherin. PEG9MA10-PAB10-GalMA10 exhibits anti-tumor efficacy in hepatoma models. PEG9MA10-PAB10-GalMA10 can be used for research on liver cancer (hepatocellular carcinoma) [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
