40 Results for "

MLCK

" in MedChemExpress (MCE) Product Catalog:
Products (40)

40 Results for "MLCK" in MCE Product Catalog:

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Cat. No.: HY-RS08925
Research Areas:  

Others

MYLK3 Human Pre-designed siRNA Set A contains three designed siRNAs for MYLK3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P3965A
Target:  

Myosin

Research Areas:  

Neurological Disease

16-38-Thymosin β4 (cattle) TFA is a Ca 2+-independent MLCK activator with high affinity .
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Cat. No.: HY-P5998
CAS No.: 119386-41-3
Target:  

Myosin

Research Areas:  

Cancer

Myosin Light Chain Kinase Substrate (smooth muscle) is a smooth muscle myosin light chain kinase (MLCK) synthetic peptide substrate .
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Cat. No.: HY-RS08924
Research Areas:  

Others

MYLK2 Human Pre-designed siRNA Set A contains three designed siRNAs for MYLK2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS18624
Research Areas:  

Others

Mylk Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mylk gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-176882
CAS No.: 2247064-44-2
Target:  

ASK1 TNF Receptor

Research Areas:  

Inflammation/Immunology

ASK1-IN-11 (Compound 7) is an apoptosis signal-regulating kinase 1 (ASK1) inhibitor with an IC50 <200 nM. ASK1-IN-11 also shows inhibitory activities to TNF-α, MYLK/MLCK Kinase and hERG potassium channels . ASK1-IN-11 can be used for the research of inflammation .
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Cat. No.: HY-RS08923
Research Areas:  

Others

MYLK Human Pre-designed siRNA Set A contains three designed siRNAs for MYLK gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P10166
CAS No.: 209251-66-1
Target:  

Inhibitory Antibodies

Research Areas:  

Others

MLCK Peptide, control is a myosin light-chain kinase. Adding MLCK peptide to permeabilized L15 cells dramatically decreased IICR. MLCK peptide caused a reduction in the extent of IICR with no change in the affinity of IP3 for the IP3R .
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Cat. No.: HY-13692
CAS No.: 187935-17-7
Synonyms: CARD-024
Research Areas:  

Inflammation/Immunology

1α-Hydroxyvitamin D5 (CARD-024) is a vitamin D analog with extremely low hypercalcemic effects. 1α-Hydroxyvitamin D5 effectively attenuates the pro-fibrotic response of colonic myofibroblasts to TGFβ and high-stiffness substrates by inhibiting the expression of αSMA, the phosphorylation of FAK, and the gene expression of MLCK and ET-1, while activating the anti-inflammatory pathway of IL-1β/COX-2. 1α-Hydroxyvitamin D5 can be used in research related to intestinal fibrosis associated with Crohn's disease .
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Cat. No.: HY-P84598A
Synonyms: KRP; AAT7; MLCK; MLCK1; MMIHS; MYLK1; smMLCK; MLCK108; MLCK210; MSTP083

Host:  

Mouse

Application:  

WB, IHC-P, ICC/IF, FC, ELISA

Reactivity:  

Human, Mouse

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Cat. No.: HY-P703167
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: MYLK; MLCK210; Myosin Light Chain Kinase; MYLK-L; Telokin; Smooth Muscle Myosin Light Chain Kinase; SmMLCK; Myosin, Light Polypeptide Kinase; MYLK1; Long Myosin Light Chain Kinase; MLCK1; Kinase Related Protein; MLCK; MYLK Protein; KRP; MSTP083; Myosin Li
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P706151
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MYLK; MLCK210; Myosin Light Chain Kinase; MYLK-L; Telokin; Smooth Muscle Myosin Light Chain Kinase; SmMLCK; Myosin, Light Polypeptide Kinase; MYLK1; Long Myosin Light Chain Kinase; MLCK1; Kinase Related Protein; MLCK; MYLK Protein; KRP; MSTP083; Myosin Light Chain Kinase, Smooth Muscle; MMIHS1; Kinase-Related Protein; MMIHS; MLCK108; AAT7
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P84598
Synonyms: KRP; AAT7; MLCK; MLCK1; MMIHS; MYLK1; smMLCK; MLCK108; MLCK210; MSTP083

Host:  

Mouse

Application:  

WB, IHC-P, ICC/IF, FC, ELISA

Reactivity:  

Human, Mouse

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Cat. No.: HY-P80236
Synonyms: MLCK, MLCK1, MYLK1, MYLK, smMLCK, Kinase-related protein, Telokin, KRP

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P83388
Synonyms: KMLS; KRP; MLCK; MYLK; myosin light chain kinase; smooth muscle and non-muscle isozymes; myosin light polypeptide kinase; telokin

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-N19735
CAS No.: 144678-18-2
MS-347a is an inhibitor of myosin light chain kinase (MLCK) and protein kinase C (PKC), with IC50 values of 9.2 μM, 31 μM and 16 μM against calmodulin-dependent MLCK, calmodulin-independent MLCK and PKC, respectively. MS-347a binds to the catalytic domain of MLCK and blocks both calmodulin-dependent and calmodulin-independent MLCK activity. MS-347a inhibits the growth of drug-sensitive fission yeast and multiple ascomycete phytopathogenic fungi. MS-347a exhibits fungicidal activity against a variety of phytopathogenic fungi and protective activity against Magnaporthe oryzae in rice seedlings. MS-347a shows antibacterial activity against specific Gram-positive bacteria and Proteus vulgaris. MS-347a can be used in studies related to rice blast, bacterial infections and phytopathogenic fungal diseases .
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Cat. No.: HY-100932R
CAS No.: 105637-50-1
Research Areas:  

Cancer

ML-9 (Standard) is the analytical standard of ML-9 (HY-100932). This product is intended for research and analytical applications. ML-9 is a selective and potent inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK) and stromal interaction molecule 1 (STIM1) activity . ML-9 inhibits inhibits MLCK, PKA and PKC activity with Ki values of 4, 32 and 54 μM, respectively . ML-9 induces autophagy by stimulating autophagosome formation and inhibiting their degradation .
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Cat. No.: HY-W718178
CAS No.: 152-84-1
Ruberythric acid is a natural product found in madder (Rubia tinctorum). Acid treatment induces hydrolysis of Ruberythric acid, producing pentose-containing sugar residues and alizarin. Ruberythric acid inhibits stimulus-induced phosphorylation of IKK, IκBα and p65 in the NF-κB pathway, regulates tight junction integrity, suppresses stimulus-induced MLCK activation and myosin light chain phosphorylation, reduces tight junction disruption associated with cytoskeletal contraction, alleviates stimulus-induced increase in intestinal permeability, and prevents stimulus-induced redistribution of tight junction proteins. Ruberythric acid forms red salts when dissolved in alkali and can be used as a dye. Ruberythric acid is applicable to research related to inflammatory bowel disease .
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Cat. No.: HY-P703411
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: MYLK4; CaMLCK Like; Myosin Light Chain Kinase Family Member 4; Myosin Light Chain Kinase Family, Member 4; SgK085; SGK085; Sugen Kinase 85; MLCK4
Species:  
Human
Source:  
Sf9 insect cells
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