Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
70 Results for "
Periodontitis
" in MedChemExpress (MCE) Product Catalog:
Products (70)
70 Results for "Periodontitis" in MCE Product Catalog:
Target:
Cat. No.: HY-N2156
CAS No.: 72520-92-4
Cat. No.: HY-W010253
CAS No.: 538-32-9
Category:
Research Areas:
DS96432529 is an orally active CDK8 inhibitor with an IC50 of 33 nM. DS96432529 enhances ALPase activity, with an EC200 of 63 nM. DS96432529 inhibits TNF-α-induced activation of the RLR signaling pathway, activates mitophagy, accelerates mineralized nodule formation, and suppresses the proliferation of periodontal ligament stem cells. DS96432529 promotes bone formation, alleviates ligation-induced alveolar bone loss, and increases bone mineral density in ovariectomized animal models. DS96432529 can be used in studies related to periodontitis and osteoporosis .
Cat. No.: HY-128736C
Purity: 89.70%
Target:
Synonyms: ATB-346
Research Areas:
Otenaproxesul (ATB-346), an orally active non-steroidal anti-inflammatory drug (NSAID), inhibits cyclooxygenase-1 and 2 (COX-1 and 2). Otenaproxesul possesses antiinflammatory and antinociceptive activities .
Cat. No.: HY-D0830
CAS No.: 1170856-93-5
Synonyms: Fluorexon tetraethyl ester
Cat. No.: HY-B0330R
CAS No.: 100986-85-4
Synonyms: (-)-Ofloxacin (Standard)
Levofloxacin (Standard) is the analytical standard of Levofloxacin. This product is intended for research and analytical applications. Levofloxacin ((-)-Ofloxacin) is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin inhibits the DNA gyrase and topoisomerase IV. Levofloxacin can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin shows anti-orthopoxvirus activity .
Cat. No.: HY-N3831
CAS No.: 161068-53-7
Cat. No.: HY-128736
CAS No.: 23295-92-3
Target:
Cat. No.: HY-P2302
CAS No.: 136661-76-2
Target:
Research Areas:
Cat. No.: HY-100210A
Purity: 99.81%
Target:
Research Areas:
FN-439 TFA is a selective collagenase-1 inhibitor. FN-439 TFA inhibits collagenase-1 with an IC50 value of 1 μM. FN-439 TFA can be used for the research of cancer and inflammation .
Cat. No.: HY-B0330BR
CAS No.: 177325-13-2
Synonyms: (-)-Ofloxacin hydrochloride (Standard)
Target:
Reference Standards Antibiotic Bacterial DNA/RNA Synthesis Topoisomerase Orthopoxvirus Apoptosis
Research Areas:
Levofloxacin (hydrochloride) (Standard) is the analytical standard of Levofloxacin hydrochloride (HY-B0330B). This product is intended for research and analytical applications. Levofloxacin hydrochloride is an orally active antibiotic. Levofloxacin inhibits DNA gyrase and topoisomerase IV activity, inducing Apoptosis. Levofloxacin hydrochloride has antibacterial activity against both Gram-positive and Gram-negative bacteria. Levofloxacin hydrochloride exhibits anticancer activity against lung cancer. Levofloxacin hydrochloride has anti-acnegenic, anxiogenic, and analgesic effects. Levofloxacin hydrochloride shortens sleep duration in mice. Levofloxacin hydrochloride can be used in the research of infectious diseases (such as tuberculosis, chronic periodontitis, bacterial infections associated with stable COPD, and BK viremia) and lung cancer .
Cat. No.: HY-W004294S1
CAS No.: 169398-02-1
Cat. No.: HY-P1789A
Target:
Research Areas:
Cat. No.: HY-129991
CAS No.: 874887-03-3
Target:
Research Areas:
JNJ-17166864 is a highly selective CCR2 antagonist. JNJ-17166864 has low oral bioavailability. JNJ-17166864 can significantly reduce the area of alveolar bone loss in a mouse model of periodontitis induced by Porphyromonas gingivalis infection. JNJ-17166864 can be used in the research of inflammatory diseases such as allergic rhinitis and periodontitis .
Cat. No.: HY-113721
CAS No.: 104062-70-6
Target:
Research Areas:
BML-244 is a potent cathepsin K inhibitor. BML-244 can be used in the study of rheumatoid arthritis (RA) and periodontitis .
Cat. No.: HY-B0330C
CAS No.: 872606-49-0
Synonyms: (-)-Ofloxacin sodium
Research Areas:
Levofloxacin ((-)-Ofloxacin) sodium is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin sodium inhibits the DNA gyrase and topoisomerase IV. Levofloxacin sodium can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin sodium shows anti-orthopoxvirus activity .
Cat. No.: HY-B0330AR
CAS No.: 138199-71-0
Synonyms: Levofloxacin hemihydrate (Standard)
Levofloxacin (hydrate) (Standard) is the analytical standard of Levofloxacin (hydrate). This product is intended for research and analytical applications. Levofloxacin hydrate (Levofloxacin hemihydrate) is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin hydrate inhibits the DNA gyrase and topoisomerase IV. Levofloxacin hydrate can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin hydrate shows anti-orthopoxvirus activity .
Cat. No.: HY-162280
CAS No.: 3034024-77-3
Research Areas:
PROTAC BTK Degrader-9 is a potent BTK PROTAC degrader with a DC50 of 1.29 nM (in Mino cells at 4 h). PROTAC BTK Degrader-9 induces the formation of a stable ternary complex with BTK and the CRBN E3 ubiquitin ligase, thereby mediating proteasomal degradation of BTK in a CRBN-dependent manner. PROTAC BTK Degrader-9 downregulates the RANKL-activated BTK-PLCγ2-Ca 2+-NFATc1 signaling pathway. PROTAC BTK Degrader-9 alleviates alveolar bone resorption in periodontitis models of Mus musculus (house mouse). PROTAC BTK Degrader-9 can be used in research related to periodontitis .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
