Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1010 Results for "
variant
" in MedChemExpress (MCE) Product Catalog:
Products (1010)
1010 Results for "variant" in MCE Product Catalog:
4
4
Category:
Simaroubaceae Ailanthus altissima (Mill.) Swingle Terpenoids Diterpenoids Plants Disease Research Fields Inflammation/Immunology
Target:
4
4 Cited Publications
Cat. No.: HY-P7846
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BRD4; Mitotic Chromosome-Associated Protein; Bromodomain Containing 4; Bromodomain-Containing Protein 4; HUNKI; Chromosome-Associated Protein; HUNK1; Bromodomain-Containing Protein 4 variant; MCAP; Bromodomain-Containing 4; CAP; Protein HUNK1; FSHRG4; BRD4 Protein; Female Sterile Homeotic Related Gene 4; CDLS6
Species:
Human
Source:
E. coli
3
Research Areas:
Galeterone (TOK-001) is a potent, orally active molecular glue degrader, which degrades androgen receptor (AR) and its splice variants (AR-Vs) and MAP kinase-interacting serine/threonine protein kinase Mnk1/2. Galeterone also functions as a CYP17 inhibitor (IC50 = 47 nM). Galeterone induces cell apoptosis. Galeterone inhibits tumor growth in human prostate cancer xenograft mouse models. Galeterone can be used for castration resistant prostate cancer (CRPC) and pancreatic ductal adenocarcinoma (PDAC) research [1][2].
3
3 Cited Publications
Cat. No.: HY-P71786
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SPP1; Uropontin; Prev. BNSP; Osteopontin/Immunoglobulin Alpha 1 Heavy Chain Constant Region Fusion Protein; Prev. OPN; CDNA FLJ54682, Highly Similar To Osteopontin; Osteopontin; Secreted Phosphoprotein 1 variant 6; Lnc-PKD2-2-3; Bone Sialoprotein I; ETA-1
Species:
Mouse
Source:
P. pastoris
2
2 Cited Publications
Cat. No.: HY-P5411
CAS No.: 148274-88-8
Synonyms: SIITFEKL, OVA (257-264) variant
2
2
2
2
2 Cited Publications
Cat. No.: HY-P70261
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GH1; Growth Hormone 1 variant 2; Growth Hormone 1; Growth Hormone 1 variant 1; GH-N; Growth Hormone 1 Isoform 1; GH; HCG1749481, Isoform CRA_aa; Pituitary Growth Hormone; Growth Hormone 1 Isoform 2; Somatotropin; HCG1749481, Isoform CRA_s; HGH-N; HCG17494
Species:
Mouse
Source:
E. coli
2
2 Cited Publications
Target:
Research Areas:
MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4), activates representative PDE4 long-isoform variants (PDE4A4, PDE4B1, PDE4C3, PDE4D5). MR-L2 suppresses PGE2-induced MDCK cell cyst formation with an EC50 of 1.2 μM .
2
2 Cited Publications
Target:
Research Areas:
STING agonist-22 (CF501) is a potent non-nucleotide STING agonist. STING agonist-22 is a adjuvant by activating STING to induce the type I interferon (IFN-I) response and proinflammatory cytokine production. STING agonist-22 can be used as an adjuvant to boost the original protein vaccine, producing potent, broad, and long-term immune protection. STING agonist-22 can be used for SARS-CoV-2 variants and sarbecovirus diseases research .
2
2 Cited Publications
Cat. No.: HY-P7467
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AGER; Receptor For Advanced Glycosylation End-Products Deletion Exon3-10 variant; Advanced Glycosylation End-Product Specific Receptor; Receptor For Advanced Glycosylation End-Products Deletion Exon2-6 variant; RAGE; Advanced Glycosylation End Product-Spe
Species:
Human
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P70422
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF3; Filgrastim; Prev. C17orf33; MGC45931; Prev. GCSF; Colony Stimulating Factor 3 Nirs variant 1; Prev. G-CSF; Granulocyte Colony Stimulating Factor; Granulocyte Colony-Stimulating Factor; Granulocyte-Colony Stimulating Factor; Pluripoietin; Chromosome
Species:
Human
Source:
E. coli
2
2 Cited Publications
Cat. No.: HY-P70554
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF3; Filgrastim; Prev. C17orf33; MGC45931; Prev. GCSF; Colony Stimulating Factor 3 Nirs variant 1; Prev. G-CSF; Granulocyte Colony Stimulating Factor; Granulocyte Colony-Stimulating Factor; Granulocyte-Colony Stimulating Factor; Pluripoietin; Chromosome
Species:
Mouse
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P79222
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SPP1; Uropontin; Prev. BNSP; Osteopontin/Immunoglobulin Alpha 1 Heavy Chain Constant Region Fusion Protein; Prev. OPN; CDNA FLJ54682, Highly Similar To Osteopontin; Osteopontin; Secreted Phosphoprotein 1 variant 6; Lnc-PKD2-2-3; Bone Sialoprotein I; ETA-1
Species:
Rat
Source:
CHO
2
2 Cited Publications
Target:
Research Areas:
(R)-SKBG-1 is a covalent inhibitor targeting the RNA binding protein NONO. (R)-SKBG-1 can reduce the expression of androgen receptor (AR) and its splice variants, inhibiting cancer cell proliferation. (R)-SKBG-1 inhibits androgen receptor expression with IC50 of 3.1 μM and 5.5 μM for AR-FL mRNA and AR-V7 mRNA, respectively. (R)-SKBG-1 interferes with the gene regulatory network of cancer cells and inhibits cancer cell growth by stabilizing the interaction between NONO and mRNA. (R)-SKBG-1 can be used in the study of cancers related to NONO dysfunction, such as prostate cancer .
2
2 Cited Publications
Cat. No.: HY-P72989
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EGFR; Epidermal Growth Factor Receptor variant EX12_14del; Prev. ERBB; Cell Proliferation-Inducing Protein 61; ERBB1; Cell Growth Inhibiting Protein 40; ERRP; Receptor Protein-Tyrosine Kinase; Receptor Tyrosine-Protein Kinase ErbB-1; Alternative Protein E
Species:
Mouse
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P72987
Purity: ≥ 75%, as determined by reducing SDS-PAGE.
Synonyms: EGFR; Epidermal Growth Factor Receptor variant EX12_14del; Prev. ERBB; Cell Proliferation-Inducing Protein 61; ERBB1; Cell Growth Inhibiting Protein 40; ERRP; Receptor Protein-Tyrosine Kinase; Receptor Tyrosine-Protein Kinase ErbB-1; Alternative Protein E
Species:
Human
Source:
Sf9 insect cells
2
2 Cited Publications
Cat. No.: HY-P71575
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TEAD4; RTEF1; Prev. TCF13L1; TEA Domain Family Member 4 Isoform 1 variant; Transcriptional Enhancer Factor TEF-3; Transcriptional Enhancer Factor 1-Related; TEA Domain Family Member 4; TEA Domain Family Member 4, Isoform CRA_b; TEFR-1; Related Transcripti
Species:
Mouse
Source:
E. coli
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
