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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
206 Results for "
5-HT3 Receptor
" in MedChemExpress (MCE) Product Catalog:
Products (206)
206 Results for "5-HT3 Receptor" in MCE Product Catalog:
1
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Sarpogrelate hydrochloride (MCI-9042) is a selective 5-HT2R antagonist, with pKis of 8.52, 6.57, and 7.43 for 5-HT2A, 5-HT2B, and 5-HT2C receptors, respectively. Sarpogrelate hydrochloride displays selectivity over 5-HT1, 5-HT3, 5-HT4, α1-, α2- and β-adrenoreceptor, histamine H1, H2 and muscarinic M3 receptors. Sarpogrelate hydrochloride can be used for the research of vascular disease associated with thrombosis .
Cat. No.: HY-B0750
CAS No.: 115956-12-2
Synonyms: MDL-73147
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Dolasetron (MDL-73147) is a serotonin 5-HT3 receptor antagonist. Dolasetron acts as an antiemetics agent and can be used for the research of chemotherapy-induced nausea and vomiting in cancer .
Cat. No.: HY-W015169
CAS No.: 608-07-1
Synonyms: O-Methylserotonin
Synonyms: N-Phenylbiguanide; PBG; 1-Phenylbiguanide
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Phenylbiguanide is a 5-HT3 receptor selective agonist with an EC50 of 3.0±0.1 μM.
Cat. No.: HY-B1541
CAS No.: 40796-97-2
Synonyms: MDL 72222
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Bemesetron (MDL 72222) is a selective 5-HT3 receptor antagonist with an IC50 of 0.33 nM . Neuroprotective effect .
Cat. No.: HY-19358
CAS No.: 78263-90-8
Synonyms: 2-Methyl-5-hydroxytryptamine; 2-Methylserotonin; 2-Me-5-HT
Target:
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2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT is shown to display anti-depressive-like effects .
Cat. No.: HY-W015169A
CAS No.: 66-83-1
Category:
Alkaloids Neurological Disease Endogenous metabolite Disease Research Fields Cancer Indole Alkaloids
Target:
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Lerisetron is a potent 5-HT3 antagonists and possess high-affinity binding for the 5-HT3 receptors with pKi value of 9.2. Lerisetron has a potent ability to inhibit the 5-HT-evoked reflex bradycardia in urethane-anesthetized rats .
Synonyms: N-Phenylbiguanide hydrochloride; PBG hydrochloride; 1-Phenylbiguanide hydrochloride
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Phenylbiguanide hydrochloride is a 5-HT3 receptor selective agonist with an EC50 of 3.0±0.1 μM.
Cat. No.: HY-B0750B
CAS No.: 878143-33-0
Synonyms: MDL-73147EF hydrate
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Dolasetron Mesylate hydrate (MDL-73147EF hydrate) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy .
Synonyms: BRL-46470
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Ricasetron (BRL-46470) is a selective and orally active 5-HT3 receptor antagonist. Ricasetron displays little or no affinity for a variety of other neurotransmitter receptors. Ricasetron has anxiolytic and antiemetic effects .
Cat. No.: HY-A0008
CAS No.: 36085-73-1
Synonyms: B-HT 920 dihydrochloride
Research Areas:
Talipexole dihydrochloride (B-HT 920 dihydrochloride) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist and 5-HT3 receptor antagonist, which displays antiParkinsonian activity.
Cat. No.: HY-12560
CAS No.: 711085-63-1
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PNU-282987 (free base) is a potent α7 nicotinic acetylcholine receptor (nAChR) agonist with an EC50 of 154 nM. PNU-282987 (free base) is also a functional antagonist of the 5-HT3 receptor with an IC50 of 4541 nM. PNU-282987 (free base) can be used for the research of central and peripheral nervous systems .
Cat. No.: HY-109543A
CAS No.: 160472-97-9
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Indisetron dihydrochloride is a 5-HT3 receptor antagonist with anti-emetic activity.
Cat. No.: HY-19199
CAS No.: 151213-86-4
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E-3620 is a potent 5-HT3 receptor antagonist. E-3620 can be used for the research of dyskinesi and gastrointestinal motility .
Cat. No.: HY-B0750A
CAS No.: 115956-13-3
Synonyms: MDL-73147EF
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Dolasetron Mesylate (MDL-73147EF) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy .
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PU02, a derivative of 6-MP (HY-13677), is a negative allosteric modulator (NAM) of 5-HT3 receptor, with IC50 values of 0.36 and 0.73 μM in HEK293 cells transfected with human 5-HT3A and 5-HT3AB receptors respectively .
Cat. No.: HY-B0352S
CAS No.: 1216678-68-0
Synonyms: Org3770 d3; 6-Azamianserin d3
Cat. No.: HY-B0352B
CAS No.: 61364-37-2
Synonyms: (R)-Org3770; (R)-6-Azamianserin
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(R)-Mirtazapine ((R)-Org3770) is a R( )-enantiomer of Mirtazapine with antinociceptive properties in an animal model of acute thermal nociception. (R)-Mirtazapine is a 5-HT3 receptor antagonist. (R)-Mirtazapine is mainly metabolized by CYP3A4 .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
