318 Results for "

CE

" in MedChemExpress (MCE) Product Catalog:
Products (318)

318 Results for "CE" in MCE Product Catalog:

Cat. No.: HY-P991565

Target:  

c-Met/HGFR

Research Areas:  

Cancer

CE-355621 is a humanized anti-c-Met IgG1 monoclonal antibody. CE-355621 can effectively bind with human c-Met (KD = 200 pM, IC50 = 466 pM) in A549 cells and cyno c-Met (KD = 610 pM) in cynomolgus kidney cells. CE-355621 inhibits the c-Met signaling pathway by blocking HGF binding. CE-355621 significantly inhibits the growth of tumors dependent on the c-Met/HGF pathway. CE-355621 can be used for research on cancer such as glioblastoma and gastric cancer .
loading...
    loading...
Cat. No.: HY-11074
CAS No.: 870615-40-0
Research Areas:  

Metabolic Disease

CE-326597 is a small molecule agonist of the cholecystokinin A receptor (CCKAR). CE-326597 occupies only the lower half of the TMD pocket and cannot mimic the crucial interaction between CCK-8 and ECL1-3. CE-326597 can be used to study metabolic diseases and gastrointestinal dysfunction .
loading...
    loading...
Cat. No.: HY-119337
CAS No.: 208840-22-6
Target:  

Ser/Thr Protease

Research Areas:  

Infection

CE-2072 is an inhibitor of serine proteases neutrophil elastase and proteinase-3. CE-2072 inhibits HIV-1 production and p24 production in response to IL-18 or NaCl in infected U1 monocytic cells, reduces virus replication in infected peripheral blood mononuclear cells and blocks infection of permissive HeLa cells. CE-2072 suppresses activation of the HIV-1-inducing transcription factor NF-kB in U1 cells. CE-2072 is promising for research of HIV-1-related disease .
loading...
    loading...
Cat. No.: HY-112423
CAS No.: 717899-97-3
Purity:  98.14%
Target:  

Trk Receptor Tie

Research Areas:  

Cardiovascular Disease Cancer

CE-245677 is a potent reversible inhibitor of Tie2 and TrkA/B kinases with a cellular IC50s of 4.7 and 1 nM.
loading...
    loading...
Cat. No.: HY-W714969A
CAS No.: 1393524-83-8
Target:  

Phosphoramidites

Research Areas:  

Others

BCN-CE-phosphoramidite is an oligonucleotide modifier containing a BCN strained cyclooctyne structure. BCN-CE-phosphoramidite possesses bioorthogonal reactivity and bioconjugation capability .
loading...
    loading...
Cat. No.: HY-P11029
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

CES (CESPLLSEC) is a homing peptide targeting Synaptosomal associated protein 25 (SNAP25). CES specifically homes in intracranial U87MG and the WT-glioblastoma (GBM) model. CES can be used as a targeting peptide for drug delivery for cancers research .
loading...
    loading...
Cat. No.: HY-141580S1
CAS No.: 2699606-99-8
Synonyms: N-octadecaoyl-D-eytho-Dihydosphigosie-d3; CE(d18:0/18:0)-d3; CEamide-d3 (d18:0/18:0-d3)
Research Areas:  

Metabolic Disease

C18 Dihydroceramide-d3-1 (N-octadecaoyl-D-eytho-Dihydosphigosie-d3) is deuterium labeled C18 Dihydroceramide. C18 Dihydroceramide is an ester product .
loading...
    loading...
Cat. No.: HY-169820
CAS No.: 956246-95-0
Target:  

Cannabinoid Receptor

Research Areas:  

Neurological Disease

CE-178253 benzenesulfonate is a CB1 antagonist with central nervous system activity.
loading...
    loading...
Cat. No.: HY-177196
CAS No.: 1582753-53-4
Research Areas:  

Others

5'-DMT-3'-CE-2'-TBDMS cyanoethoxycarbonyl-adenosine is a nucleotide analogue used in nucleic acid synthesis.
loading...
    loading...
Cat. No.: HY-177197
CAS No.: 1582753-54-5
Research Areas:  

Others

5'-DMT-3'-CE-2'-TBDMS cyanoethoxycarbonyl-cytidine is a nucleotide analogue used in nucleic acid synthesis.
loading...
    loading...
Cat. No.: HY-49214
CAS No.: 460355-05-9
Research Areas:  

Others

5-Formylindole-CE phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
loading...
    loading...
Cat. No.: HY-155755
Research Areas:  

Cancer

CES2A-IN-1 (compound 20w) is a potent CES2A inhibitor with an IC50 value of 1.6 nM for human CES2A. CES2A-IN-1, a bysspectin A derivative, shows an approximately 1000-fold improvement over the lead compound bysspectin A .
loading...
    loading...
Cat. No.: HY-173267
Research Areas:  

Metabolic Disease Cancer

CES2A-IN-2 (compound 14n) is an orally active, highly specific, irreversible and covalent CES2A inhibitor with an IC50 of 0.04 nM for human CES2A. CES2A-IN-2 covalently binds to CES2A by specifically targeting the catalytic serine residue (Ser-228). CES2A-IN-2 can significantly ameliorate Irinotecan-triggered gut toxicity (ITGT) without diminishing the anti-tumor effects of Irinotecan (HY-16562) in tumor-bearing mice .
loading...
    loading...
Cat. No.: HY-176465
CAS No.: 3037959-47-7
Research Areas:  

Inflammation/Immunology

CES2A-IN-3 (Compound 9d) is a potent serine-targeting covalent human carboxylesterase 2A (hCES2A) inhibitor with an IC50 value of 0.12 nM. CES2A-IN-3 is promising for research of diarrhea and ulcerative colitis .
loading...
    loading...
Cat. No.: HY-RS02543
Research Areas:  

Others

CES1 Human Pre-designed siRNA Set A contains three designed siRNAs for CES1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS02544
Research Areas:  

Others

CES2 Human Pre-designed siRNA Set A contains three designed siRNAs for CES2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS02545
Research Areas:  

Others

CES3 Human Pre-designed siRNA Set A contains three designed siRNAs for CES3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-W1133231
CAS No.: 1879038-73-9
CE-103 is a selective, blood-brain barrier-permeable dopamine transporter (DAT) inhibitor with an IC50 of 14.73 μM. CE-103 blocks DAT-mediated dopamine reuptake and exhibits antagonistic activity against 5-HT1A. CE-103 reduces working memory errors in the radial arm maze test of rats, decreases the levels of complexes containing phosphorylated DAT (pDAT) and D1R in the hippocampus of rats, and increases the levels of complexes containing D2R and D3R simultaneously. CE-103 can be used in studies related to dopaminergic neurotransmission, working memory and cognitive function .
loading...
    loading...
Cat. No.: HY-W1143328
CAS No.: 1120329-56-7
Target:  

Phosphoramidites

Research Areas:  

Others

UNA-C(Ac)-CE Phosphoramidite is a modified RNA building block used in automated oligonucleotide synthesis. UNA-C(Ac)-CE Phosphoramidite incorporates an acyclic "Unlocked Nucleic Acid" (UNA) cytosine monomer with an acetyl (Ac) protecting group on the base and a cyanoethyl (CE) group on the phosphoramidite
loading...
    loading...
Cat. No.: HY-182104
CAS No.: 2417413-14-8
Research Areas:  

Others

dW-CE Phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
loading...
    loading...