CE-2072
CE-2072 is an inhibitor of serine proteases neutrophil elastase and proteinase-3. CE-2072 inhibits HIV-1 production and p24 production in response to IL-18 or NaCl in infected U1 monocytic cells, reduces virus replication in infected peripheral blood mononuclear cells and blocks infection of permissive HeLa cells. CE-2072 suppresses activation of the HIV-1-inducing transcription factor NF-kB in U1 cells. CE-2072 is promising for research of HIV-1-related disease.
For research use only. We do not sell to patients.
- CAS No.: 208840-22-6
- Formula: C33H41N5O6
- Molecular Weight:603.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 208840-22-6
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Molecular Weight 603.71
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Formula C33H41N5O6
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SMILES
O=C([C@H]1N(CCC1)C([C@@H](NC(OCC2=CC=CC=C2)=O)C(C)C)=O)N[C@@H](C(C)C)C(C3=NN=C(O3)CC4=CC=CC(C)=C4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)