717899-97-3

CE-245677 Chemical Structure
717899-97-3

Chemical Structure

CE-245677

  • CAS No.: 717899-97-3
  • Formula:C24H22Cl2N6O3
  • Molecular Weight:513.38

IUPAC Name: 1-(5-(4-amino-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-2-methoxyphenyl)-3-(2,4-dichlorophenyl)urea

InChIKey: VFCRSIORGUNNGT-UHFFFAOYSA-N

SMILES: O=C(NC1=CC=C(Cl)C=C1Cl)NC2=CC(C(C3=CN(C(C)C)C4=NC=NC(N)=C43)=O)=CC=C2OC

Biological Activity: CE-245677 is a potent reversible inhibitor of Tie2 and TrkA/B kinases with a cellular IC50s of 4.7 and 1 nM.

Cat. No. Product Name Purity Description Pricing
HY-112423
CE-245677 98.00% CE-245677 is a potent reversible inhibitor of Tie2 and TrkA/B kinases with a cellular IC50s of 4.7 and 1 nM.
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