77 Results for "

DNA labeling agent

" in MedChemExpress (MCE) Product Catalog:
Products (77)

77 Results for "DNA labeling agent" in MCE Product Catalog:

Carboplatin-d4
Carboplatin-d4
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Cat. No.: HY-17393S
Synonyms: NSC 241240-d4
Carboplatin-d4 is the deuterium labeled Carboplatin. Carboplatin (NSC 241240) is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death. Carboplatin (NSC 241240) is a derivative of CDDP and a potent anti-cancer agent.
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Thymidine-13C
Thymidine-13C
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Cat. No.: HY-N1150S2
CAS No.: 478511-06-7
Synonyms: DThyd-13C; NSC 21548-13C
Thymidine- 13C is the 13C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication
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Thymidine-d3
Thymidine-d3
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Cat. No.: HY-N1150S
CAS No.: 74848-84-3
Synonyms: DThyd-d3; NSC 21548-d3
Thymidine-d3 is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication .
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Pentamidine-d4 dihydrochloride
Pentamidine-d4 dihydrochloride
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Cat. No.: HY-B0537AS
CAS No.: 1276197-32-0
Synonyms: MP-601205-d4 dihydrochloride
Pentamidine-d4 (dihydrochloride) is the deuterium labeled Pentamidine dihydrochloride. Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine dihydrochloride inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine dihydrochloride is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine dihydrochloride has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities .
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Thymidine-d2
Thymidine-d2
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Cat. No.: HY-N1150S6
CAS No.: 132376-92-2
Synonyms: DThyd-d2; NSC 21548-d2
Thymidine-d2 is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1
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Thymidine-d14
Thymidine-d14
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Cat. No.: HY-N1150S10
CAS No.: 1134181-96-6
Synonyms: DThyd-d14; NSC 21548-d14
Thymidine-d14 (DThyd-d14; NSC 21548-d14) is deuterium labeled Thymidine (HY-N1150). Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication.
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Methyl methanesulfonate-d3
Methyl methanesulfonate-d3
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Cat. No.: HY-W004702S
CAS No.: 91419-94-2
Synonyms: METHYLMETHANE SULPHONATE-d3
Methyl methanesulfonate-d3 is the deuterium labeled Methyl methanesulfonate (HY-W004702). Methyl methanesulfonate is an alkylating agent which transfers methyl groups, and induces DNA damage. Methyl methanesulfonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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Benzophenone-13C
Benzophenone-13C
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Cat. No.: HY-Y0546S2
CAS No.: 32488-48-5
Benzophenone- 13C is the 13C labeled Benzophenone (HY-Y0546). Benzophenone is an endogenous metabolite. Benzophenone is a photosensitizer, that absorbs UV light, transfers its energy to DNA, and triggers DNA damage. Benzophenone can be used as the fragrance enhancer, ultraviolet curing agent, additive in plastics, or the flavor ingredient. Benzophenone can also be used in the manufacturing of insecticides, agricultural chemicals, hypnotics, antihistamines, and other pharmaceuticals. Benzophenone exhibits certain carcinogenicity in mouse/rat models under long term exposure. Benzophenone exhibits estrogenic activity .
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Sulfabenzamide-d4
Sulfabenzamide-d4
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Cat. No.: HY-B0960S
CAS No.: 2732981-22-3
Synonyms: N-Sulfanilylbenzamide-d4
Sulfabenzamide (N-Sulfanilylbenzamide)-d4 is the deuterium labeled Sulfabenzamide (HY-B0960). Sulfabenzamide is a sulfonamide antibacterial agent. Sulfabenzamide exhibit antibacterial activity against Staphylococcus aureus (ATCC 25923) and Escherichia coli (ATCC 8739). Sulfabenzamide can promote autophagic cell autophagy in breast cancer cells through p53/ DRAM pathway. Sulfabenzamide increases caspase-3 activity, deactivates PARP1 and DNA-PK, downregulates AKT1 and AKT2. Sulfabenzamide can be used for the researches of breast cancer and bacterial infections .
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7-Methylguanine-d3
7-Methylguanine-d3
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Cat. No.: HY-113352S
CAS No.: 17829-03-7
7-Methylguanine-d3 is the deuterium labeled 7-Methylguanine . 7-Methylguanine is a metabolite of DNA methylation. It can be generated by methylating agents, and used as a probe of protein–DNA interactions and a key component of DNA sequencing method .
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Thymidine-d4
Thymidine-d4
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Cat. No.: HY-N1150S1
CAS No.: 347841-67-2
Synonyms: DThyd-d4; NSC 21548-d4
Thymidine-d4 is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication .
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Thymidine-13C-1
Thymidine-13C-1
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Cat. No.: HY-N1150S3
CAS No.: 240407-53-8
Synonyms: DThyd-13C-1; NSC 21548-13C-1
Thymidine- 13C-1 is the 13C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication
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Banoxantrone-d12 dihydrochloride
Banoxantrone-d12 dihydrochloride
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Cat. No.: HY-13562AS
CAS No.: 1562066-98-1
Purity:  95.03%
Synonyms: AQ4N-d12 dihydrochloride
Banoxantrone-d12 (dihydrochloride) is the deuterium labeled Banoxantrone dihydrochloride. Banoxantrone is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor.
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Banoxantrone-d12
Banoxantrone-d12
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Cat. No.: HY-13562S
CAS No.: 1562067-05-3
Synonyms: AQ4N d12
Banoxantrone-d12 is the deuterium labeled banoxantrone. Banoxantrone is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor.
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Budesonide-d6
Budesonide-d6
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Cat. No.: HY-W742981
CAS No.: 1134189-63-1
Budesonide-d6 is deuterium labeled Budesonide. Budesonide, an inhaled glucocortical steroid, is an orally active glucocorticoid receptor agonist. Budesonide decreases the size of lung tumors, reverses DNA hypomethylation and modulates mRNA expression of genes. Budesonide is an anti-inflammatory agent used for asthma .
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Imeglimin-d3
Imeglimin-d3
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Cat. No.: HY-14771S
Synonyms: EMD 387008-d3
Imeglimin-d3 (EMD 387008-d3) is deuterium labeled Imeglimin. Imeglimin (EMD 387008) is an oral glucose-lowering agent. Imeglimin improves insulin sensitivity. Imeglimin also reduces reactive oxygen species (ROS) production, increases mitochondrial DNA and improves mitochondrial function .
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Trifluridine-13C,15N2
Trifluridine-13C,15N2
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Cat. No.: HY-A0061S
CAS No.: 2086328-10-9
Synonyms: Trifluorothymidine-13C,15N2; 5-Trifluorothymidine-13C,15N2; TFT-13C,15N2
Trifluridine- 13C, 15N2 is the 13C and 15N labeled Trifluridine . Trifluridine (Trifluorothymidine;5-Trifluorothymidine;TFT) is an irreversible thymidylate synthase inhibitor, and thereby suppresses DNA synthesis. Trifluridine is an antiviral agent for herpes simplex virus (HSV) infection. Trifluorothymidine also has anti-orthopoxvirus activity .
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Etoposide-d4
Etoposide-d4
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Cat. No.: HY-W744243
Synonyms: VP-16-d4; VP-16-213-d4
Etoposide-d4 (VP-16-d4; VP-16-213-d4) is the deuterium labeled Etoposide (HY-13629). Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent. Etoposide inhibits topoisomerase II, thus stopping DNA replication. Etoposide induces cell cycle arrest, apoptosis and autophagy .
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Niclosamide-d3
Niclosamide-d3
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Cat. No.: HY-B0497S2
CAS No.: 2665663-60-3
Synonyms: BAY2353-d3
Niclosamide-d3 (BAY2353-d3) is deuterium labeled Niclosamide. Niclosamide (BAY2353) is an orally active antihelminthic agent used in parasitic infection research . Niclosamide is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells . Niclosamide has biological activities against cancer, inhibits DNA replication in Vero E6 cells .
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Pazufloxacin-d4
Pazufloxacin-d4
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Cat. No.: HY-B0724BS
CAS No.: 1346602-96-7
Synonyms: T3761-d4
Pazufloxacin-d4 is deuterium labeled Pazufloxacin (HY-B0724B). Pazufloxacin is an orally active fluoroquinolone antimicrobial agent. Pazufloxacin inhibits DNA gyrase with IC50 values of 0.88 μg/mL (E. coli) and 1.9 μg/mL (P. aeruginosa). Pazufloxacin exhibits broad-spectrum antimicrobial activity, with MIC90 values ranging from 0.025 to 100 μg/mL against Gram-positive and Gram-negative bacteria, non-fermenting bacteria, Legionella spp., and anaerobic bacteria. Pazufloxacin is indicated for research on systemic infections, lung infections, urinary tract infections, and Legionella pneumonia .
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