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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
99 Results for "
Polyketide
" in MedChemExpress (MCE) Product Catalog:
Products (99)
99 Results for "Polyketide" in MCE Product Catalog:
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Ethylmalonyl-CoA (Ethylmalonyl coenzyme A) is a metabolic intermediate and biosynthetic precursor associated with crotonyl-CoA carboxylase/reductase. Ethylmalonyl‑CoA is generated via the reductive carboxylation of crotonyl-CoA catalyzed by crotonyl-CoA carboxylase/reductase (CCR); it can be recognized by the PKS acyltransferase AT and participate in the biosynthesis of antibiotic polyketide natural products. Ethylmalonyl-CoA is used in biosynthesis-related research .
Cat. No.: HY-100710
CAS No.: 186692-73-9
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Epothilone C is a polyketide natural product. Epothilone C is produced by the combined action of one nonribosomal peptide synthetase (NRPS) and nine polyketide synthase (PKS) modules in a multienzyme system. Epothilone C can be used for tumor research .
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Microorganisms Ketones, Aldehydes, Acids Marine natural products Other Diseases Phenols Polyphenols Disease Research Fields Marine microorganism
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Cat. No.: HY-139594
CAS No.: 2345638-96-0
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Polyketide synthase 13-IN-1 (compound 32) is a polyketide synthase 13 inhibitor .
Cat. No.: HY-122534
CAS No.: 808750-39-2
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Mensacarcin, a highly complex polyketide, strongly inhibits cell growth universally in cancer cell lines and potently induces apoptosis in melanoma cells. Mensacarcin targets to mitochondria, affects energy metabolism in mitochondria, and activates caspase-dependent apoptotic pathways. Mensacarcin, an antibiotic, can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .
Cat. No.: HY-13557R
CAS No.: 104987-12-4
Synonyms: Immunomycin (Standard); FR-900520 (Standard); FK520 (Standard)
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Microorganisms Macrolide Antibiotics Antifungal Anti-inflammation/Immunoregulatory Antibiotics Disease Research
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Cat. No.: HY-166309
CAS No.: 116912-55-1
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Crotonyl-CoA tetralithium, a high-energy acyl donor, is an intermediate in the fermentation of butyric acid, and in the metabolism of lysine and tryptophan. Crotonyl-CoA tetralithium is important in the metabolism of fatty acids and amino acids. Crotonyl-CoA tetralithium acts as a substrate for p300’s histone crotonyltransferase activity, competing with acetyl-CoA for p300-mediated histone acylation reactions. Crotonyl-CoA tetralithium regulates global and gene-specific histone crotonylation levels in cells, with cellular concentration changes altering histone crotonylation at regulatory elements of activated genes. Crotonyl-CoA tetralithium serves as the substrate for crotonyl-CoA reductase/carboxylase (CCRC)-catalyzed NADPH-mediated reduction and carbon dioxide trapping to form unusual alkylmalonyl-CoA polyketide synthase extender units. Crotonyl-CoA tetralithium can be used for the research of LPS-induced inflammatory response .
Cat. No.: HY-N16397
CAS No.: 95730-85-1
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Cat. No.: HY-W775186
CAS No.: 911499-62-2
Tolprocarb is an oomyces fungicide, which has a strong inhibitory effect on rice blast fungus Magnaporthe grisea by inhibiting polyketide synthase in melanin synthesis pathway .
Cat. No.: HY-156047
CAS No.: 143452-11-3
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Cat. No.: HY-139595
CAS No.: 2219338-48-2
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Polyketide synthase 13-IN-2 (comp 42) is a polyketide synthase 13 inhibitor against Mycobacterium tuberculosis, with an MIC of 0.25 μg/mL .
Cat. No.: HY-139596
CAS No.: 2221801-50-7
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Polyketide synthase 13-IN-3 (compound 41) is a polyketide synthase 13 inhibitor，with a MIC of 0.0625-0.125 μg/mL against the M. tuberculosis strain H37Rv .
Cat. No.: HY-114461
CAS No.: 147025-57-8
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FD-895 is a spliceosome modulator derived from a polyketide natural product, targeting the SF3b subunit of the spliceosome. FD-895 possesses core biological activities for regulating RNA splicing (intron retention, alternative splicing) and inducing apoptosis of cancer cells. FD-895 can be used for the research of cancer, such as chronic lymphocytic leukemia (CLL) .
Cat. No.: HY-W663230
CAS No.: 480-12-6
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Cat. No.: HY-W783829
CAS No.: 10018-93-6
Synonyms: Hex-2-trans-enoyl-CoA
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(2E)-Hexenoyl-CoA (Hex-2-trans-enoyl-CoA) is an intermediate in fatty acid metabolism. (2E)-Hexenoyl-CoA undergoes reductive carboxylation to yield butylmalonyl-CoA .
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2-Methylbutyryl-CoA is a branched-chain acyl-CoA substrate. It serves as the preferred substrate for potato 2-methylbutyryl-CoA dehydrogenase (2MBCD), which catalyzes its α,β-dehydrogenation .
Cat. No.: HY-N10302
CAS No.: 1357824-71-5
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Cat. No.: HY-W748023
CAS No.: 1402990-52-6
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
