![d[Cha4]-AVP TFA](https://file.medchemexpress.com/product_pic/hy-p1390a.gif "Click to View d[Cha4]-AVP TFA Product Detail")
Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
83 Results for "
V2
" in MedChemExpress (MCE) Product Catalog:
Products (83)
83 Results for "V2" in MCE Product Catalog:
Cat. No.: HY-18344
CAS No.: 185913-78-4
Synonyms: SR 121463
Target:
Research Areas:
Satavaptan (SR 121463) is an antagonist for vasopressin V2 receptor. Satavaptan regulates the vasopressin regulated phosphopeptides and vasopressin-mediated signaling pathway. Satavaptan is potential in ameliorating hyponatremia .
Cat. No.: HY-109133
CAS No.: 1914998-56-3
Synonyms: BAY 1753011
Target:
Research Areas:
Pecavaptan, a chemical probe, is an orally active and dual antagonist of V1a/V2 receptor (Ki=0.5 nM and 0.6 nM for human, respectively). Pecavaptan promotes an increase in urine production, which reduces the associated symptoms of water retention and edema .
Cat. No.: HY-P0049A
CAS No.: 75499-44-4
Synonyms: Arg8-vasopressin diacetate; AVP diacetate; ADH
Target:
Research Areas:
Cat. No.: HY-RS03483
Target:
Research Areas:
CYP4V2 Human Pre-designed siRNA Set A contains three designed siRNAs for CYP4V2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P0272A
CAS No.: 1610056-01-3
Cat. No.: HY-18346R
CAS No.: 137975-06-5
Synonyms: OPC-31260 (Standard)
Research Areas:
Cardiovascular Disease Metabolic Disease Endocrinology Cancer
Mozavaptan (Standard) is the analytical standard of Mozavaptan. This product is intended for research and analytical applications. Mozavaptan (OPC-31260) is a benzazepine derivative and a potent, selective, competitive and orally active vasopressin V2 receptor antagonist with an IC50 of 14 nM. Mozavaptan shows ~85-fold selectivity for V2 receptor over V1 receptor (IC50 of 1.2 μM), and can antagonize the antidiuretic action of arginine vasopressin (AVP) in vivo. Mozavaptan has the potential for hyponatremia, syndrome of inappropriate antidiuretic hormone (SIADH), and congestive heart failure treatment [2].
Target:
Research Areas:
Tolvaptan phosphate ester sodium, a prodrug of Tolvaptan (HY-17000), can be used in the study of cardiac edema. Tolvaptan is a selective, competitive and orally active vasopressin receptor 2 (V2R) antagonist with an IC50 of 1.28 μM for the inhibition of arginine vasopressin (AVP)-induced platelet aggregation [2].
Cat. No.: HY-P1390A
Target:
Research Areas:
Cat. No.: HY-168742
Target:
Research Areas:
V1a/V2 antagonist 1 (Compound 18j) is an orally active dual V1a and V2 receptor antagonist with high binding affinity for both receptors (Ki: 0.13 nM for hV1a, 0.53 nM for hV2 and 0.5 nM for mV1a; IC50: 2.2 nM for hV1a). V1a/V2 antagonist 1 inhibits Oxytocin (HY-17571)-induced scratching behavior in mice .
Cat. No.: HY-14185R
CAS No.: 168079-32-1
Synonyms: VPA-985 (Standard); WAY-VPA 985 (Standard)
Research Areas:
Lixivaptan (Standard) is the analytical standard of Lixivaptan. This product is intended for research and analytical applications. Lixivaptan (VPA-985, WAY-VPA 985) is an orally active and selective vasopressin receptor V2 antagonist, with IC50 values of 1.2 and 2.3 nM for human and rat V2, respectively.
Cat. No.: HY-109181
CAS No.: 2379889-71-9
Synonyms: SK-1404; KRP-N118
Target:
Research Areas:
Lazuvapagon (SK-1404) is a vasopressin V2 receptor agonist for the research of nocturia .
Cat. No.: HY-158163
CAS No.: 3038564-39-2
Target:
Research Areas:
Herbicidal agent 4 (compound V-2) is an auxinic herbicidal agent. Herbicidal agent 4 may also be an immune activator while upregulating the defense genes and increasing content of jasmonic acid .
Cat. No.: HY-123593R
CAS No.: 138470-70-9
Synonyms: OPC-31260 hydrochloride (Standard)
Research Areas:
Cardiovascular Disease Metabolic Disease Endocrinology Cancer
Mozavaptan (hydrochloride) (Standard) is the analytical standard of Mozavaptan (hydrochloride). This product is intended for research and analytical applications. Mozavaptan hydrochloride (OPC-31260 hydrochloride) is a benzazepine derivative and a potent, selective, competitive and orally active vasopressin V2 receptor antagonist with an IC50 of 14 nM. Mozavaptan hydrochloride shows ~85-fold selectivity for V2 receptor over V1 receptor (IC50 of 1.2 μM), and can antagonize the antidiuretic action of arginine vasopressin (AVP) in vivo. Mozavaptan hydrochloride has the potential for hyponatremia, syndrome of inappropriate antidiuretic hormone (SIADH), and congestive heart failure treatment [2].
Cat. No.: HY-P1810
CAS No.: 1647119-71-8
Target:
Research Areas:
Cat. No.: HY-18346S
CAS No.: 2750534-83-7
Synonyms: OPC-31260-d6
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
