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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
38 Results for "
solid-phase oligonucleotide synthesis
" in MedChemExpress (MCE) Product Catalog:
Products (38)
38 Results for "solid-phase oligonucleotide synthesis" in MCE Product Catalog:
Cat. No.: HY-186139
CAS No.: 2133853-85-5
Synonyms: TrpdU CEP
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Trp-dU Phosphoramidite (TrpdU CEP) is a phosphoramidite monomer modified with a tryptophan moiety (Trp, indole ring) attached via a linker to the C5 position of 2'-deoxyuridine (dU), used for solid-phase oligonucleotide synthesis.
Cat. No.: HY-188073
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U(f)U(ome) Phosphoramidite is a dimeric phosphoramidite monomer composed of 2'-fluorouridine (2'-F-U) and 2'-O-methyluridine (2'-OMe-U), used for solid-phase oligonucleotide synthesis.
Cat. No.: HY-W1061634
CAS No.: 164394-19-8
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5'-Amino-modifier C6-Fmoc Phosphoramidite is a non-nucleoside phosphoramidate monomer used in solid-phase oligonucleotide synthesis to introduce a protected primary amino group (-NH2) at the 5' end of DNA/RNA.
Cat. No.: HY-W1061585
CAS No.: 136949-85-4
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DNP Phosphoramidite is a non-nucleoside-based phosphoramidite carrying a 2,4-dinitrophenyl (DNP) hapten group, which enables multiple labeling of oligonucleotides during solid-phase synthesis. DNP Phosphoramidite binds to anti-DNP antibodies, allowing the detection of labeled oligonucleotides via enzyme-linked colorimetric techniques .
Cat. No.: HY-185906
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DBCO Phosphoramidite is a phosphoramidite reagent containing a dibenzocyclooctyne (DBCO) moiety, which can introduce a strain-promoted alkyne group for copper-free click chemistry into DNA strands during solid-phase oligonucleotide synthesis. DBCO Phosphoramidite is applicable to studies related to oligonucleotide modification, copper-free click conjugation, and functionalized DNA nanomaterials .
Cat. No.: HY-W1061733
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TAO-F Phosphoramidite is a type of phosphoramidite monomer that can be used for solid-phase synthesis of oligonucleotides. TAO-F Phosphoramidite is used to prepare fluorescent-labeled probes and primers, and is widely applied in real-time quantitative PCR (qPCR), fluorescence in situ hybridization (FISH), and microarray molecular diagnostic techniques.
Cat. No.: HY-177789
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2',3'-ddT Phosphoramidite is a specially modified nucleotide monomer that is specifically used for solid-phase oligonucleotide synthesis. Once 2',3'-ddT Phosphoramidite is incorporated at the end of a DNA chain, it cannot continue to extend through normal phosphodiester bonds, and thus can also be used as a chain terminator.
Cat. No.: HY-185909
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Dodecanamido C7 Phosphoramidite is a lipophilic modifying reagent used for solid-phase oligonucleotide synthesis. Dodecanamido C7 Phosphoramidite can introduce a lauric acid (dodecanoic acid) side chain at the terminus or interior of DNA or RNA chains, and is mainly used to enhance the cell membrane penetration ability and delivery efficiency of nucleic acid reagents.
Cat. No.: HY-P11685
CAS No.: 2245800-85-3
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Cat. No.: HY-W1061415
CAS No.: 2378004-17-0
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5'-Aqp 593 Phosphoramidite hexafluorophosphate is a cyanin-based fluorescent phosphoridamide monomer suitable for solid-phase oligonucleotide synthesis. It allows for site-specific labeling of the 5' end of DNA and RNA with the AquaPhluor 593 fluorescent dye. 5'-Aqp 593 Phosphoramidite hexafluorophosphate can be used to synthesize 5'-terminal fluorescently labeled oligonucleotides for various fluorescence experiments.
Cat. No.: HY-185911
Amino-modifier C6 dC(N-Bz) Phosphoramidite is a modified deoxycytidine synthesis monomer featuring an amino group attached via a six-carbon spacer arm. Amino-modifier C6 dC(N-Bz) Phosphoramidite allows for the site-specific incorporation of an amino group during the solid-phase synthesis of DNA oligonucleotides, enabling conjugation with functional moieties—such as fluorescent groups, peptides, or biotin—to produce functional nucleic acid probes.
Cat. No.: HY-185910
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Palmitamido-C7 CE-Phosphoramidite is a long-chain esterified phosphoramidite monomer used for solid-phase oligonucleotide synthesis. Palmitamido-C7 CE-Phosphoramidite is formed by linking palmitamido to the active end of 2-cyanoethyl phosphoramidite via a C7 alkyl spacer arm. Palmitamido-C7 CE-Phosphoramidite can be used as a building block for nucleic acid chemical modification to synthesize ester-coupled oligonucleotides.
Cat. No.: HY-138586S
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Isotope-Labeled Compounds DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Phosphoramidites
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DMT-dC(ac) Phosphoramidite- 13C9, 15N3 is the 13C, 15N-labeled DMT-dC(ac) Phosphoramidite (HY-138586). DMT-dC (ac) Phosphoramidite is a phosphoramidite used for incorporating N4-acetyl deoxycytidine into oligonucleotides. DMT-dC (ac) Phosphoramidite enables the synthesis of modified DNA sequences via standard solid-phase chemistry. DMT-dC (ac) Phosphoramidite is used in research on oligonucleotide synthesis .
Cat. No.: HY-185907
CAS No.: 1772522-17-4
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5'-Octyltocopherol C8 CE Phosphoramidite is a tocopherol-based phosphoramidite modification monomer for solid-phase oligonucleotide synthesis, which can introduce an octyltocopherol modification group with a C8 spacer arm at the 5'-end of oligonucleotides. 5'-Octyltocopherol C8 CE Phosphoramidite can be used to prepare DNA or RNA with hydrophobic tocopherol terminal modifications. 5'-Octyltocopherol C8 CE Phosphoramidite is applicable to studies related to oligonucleotide chemical synthesis, nucleic acid hydrophobic modification, and nucleic acid conjugate construction.
Cat. No.: HY-183383
CAS No.: 144303-74-2
Synonyms: 4-Thio-DU CEP
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4-Thio-dU CE phosphoramidite (4-Thio-DU CEP) is a special modified nucleotide unit of thymine/uracil structure, used in solid-phase oligonucleotide synthesis to introduce the protected 4-sulfur carbonyl group into the DNA or RNA chain. 4-Thio-dU CE phosphoramidite is mainly used for photocrosslinking, photophilic labeling, nucleic acid structure research, and site-specific functionalization through sulfur atoms after synthesis.
Cat. No.: HY-W1119956
CAS No.: 3103531-71-8
Synonyms: 5'(E)-VP-2'-OMe-iBu-G
Phosphoramidite
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5'-(E)-VPG Phosphoramidite (5'(E)-VP-2'-OMe-iBu-GPhosphoramidite) is a structurally modified phosphoramidite reagent used to synthesize biologically stable oligonucleotides. 5'-(E)-VPG Phosphoramidite (POM) carries a VP protecting group and can be coupled to the target oligonucleotide at the 5' end via solid-phase synthesis. The modified oligonucleotide is then constructed through oxidation and deprotection steps. 5'-(E)-VPG Phosphoramidite is suitable for RNAi and viral replication research .
Cat. No.: HY-185901
Cat. No.: HY-W1061747
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endo-BCN-PEG3 Phosphoramidite is a nucleic acid phosphoramidite modifier containing an endo-bicyclononyne (BCN) group and a PEG3 spacer, enabling site-specific incorporation of endo-BCN-PEG3 into DNA or RNA during solid-phase oligonucleotide synthesis. endo-BCN-PEG3 Phosphoramidite introduces a BCN group that can undergo copper-free strain-promoted azide-alkyne cycloaddition (SPAAC) with azide-containing molecules or inverse electron demand Diels-Alder (IEDDA) reactions with tetrazines, enabling post-synthetic oligonucleotide labeling and bioconjugation.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
