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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
158 Results for "
tumor development
" in MedChemExpress (MCE) Product Catalog:
Products (158)
158 Results for "tumor development" in MCE Product Catalog:
Referencia número: HY-165740
No. CAS: 65988-71-8
Synonyms: Disialoganglioside GD2
Ganglioside GD2 (Disialoganglioside GD2) is a tumor-associated antigen. Ganglioside GD2 shows limited expression in normal tissues but is overexpressed in multiple tumor types, and thus can serve as a target in cancer. Ganglioside GD2 is associated with tumor development and malignant phenotypes, and its mechanism of action relies on enhancing cell proliferation, motility, migration, adhesion and invasion, with specific effects depending on the tumor type .
Referencia número: HY-W013272
No. CAS: 52806-53-8
Synonyms: HFT
Áreas de investigación:
Hydroxyflutamide (HFT) is the active metabolite of Flutamide (HY-B0022) and exhibits oral activity. Hydroxyflutamide is a potent androgen receptor antagonist with an IC50 of 700 nM. Hydroxyflutamide can affect embryonic development and reproductive tract development in mice. Additionally, Hydroxyflutamide can enhance the efficacy of Bacillus Calmette-Guérin (BCG) to better inhibit the progression of bladder cancer. Hydroxyflutamide can be used in research related to tumors and reproductive diseases .
Category:
Alkaloids Loganiaceae Extract Plants Gelsemium eleganis (Gardn. et Champ.) Benth. Disease Research Fields Inflammation/Immunology Indole Alkaloids
Target:
Target:
Áreas de investigación:
Tropinone is an organic synthesis intermediate and a skeleton for constructing derivatives containing thiazole rings and other structures. Tropinone derivatives have anticancer activities such as inducing tumor cell apoptosis and inhibiting tyrosinase activity, and can be used in research such as anticancer drug development and tyrosinase inhibitor design .
Referencia número: HY-P10131
No. CAS: 2803421-14-7
Áreas de investigación:
Referencia número: HY-W142432
No. CAS: 2058-94-8
Áreas de investigación:
Perfluoroundecanoic acid is a perfluoroalkyl substance (PFAS). Perfluoroundecanoic acid is an orally active oxidative stress inducer. Perfluoroundecanoic acid promotes macrophage M2 polarization, activates Wnt/β-catenin signaling and enhances β-catenin nuclear accumulation. Perfluoroundecanoic acid -induced M2 phenotype macrophage accelerates tumor progression in vitro and in vivo. Perfluoroundecanoic acid induces DNA damage, reproductive and pathophysiological dysfunctions via oxidative stress in male Swiss mice. Perfluoroundecanoic acid inhibits Leydig cell development in pubertal male rats via inducing oxidative stress and autophagy. Perfluoroundecanoic acid accelerates insulitis development in a mouse model of type 1 diabetes. Perfluoroundecanoic acid can be used for the study of ovarian cancer, type 1 diabetes and inflammation .
Referencia número: HY-B0006C
No. CAS: 95093-99-5
Synonyms: (R)-BM 14190
Target:
Áreas de investigación:
(R)-Carvedilol ((R)-BM 14190) is the orally active R-isomer of Carvedilol (HY-B0006). (R)-Carvedilol has α-receptor blocking activity but no β-receptor blocking activity. (R)-Carvedilol inhibits spontaneous Ca 2+ waves. (R)-Carvedilol inhibits stress-induced ventricular tachycardia and delays the development of UV-induced skin tumors and reduces their malignancy .
Referencia número: HY-P99687
No. CAS: 2552814-07-8
Synonyms: AMG 256
Target:
Áreas de investigación:
Referencia número: HY-P4102
No. CAS: 1810853-35-0
Target:
Áreas de investigación:
Referencia número: HY-W613220
No. CAS: 2143473-95-2
Áreas de investigación:
MDH1/2-IN-1 is a MDH1/2 inhibitor (IC50: 1.07 μM and 1.06 μM respectively). MDH1/2-IN-1 inhibits mitochondrial respiration and the HIF-1α pathway. MDH1/2-IN-1 demonstrates significant anti-tumor potential. MDH1/2-IN-1 provides a new direction for the development of drugs targeting cancer metabolism .
Referencia número: HY-A0096R
No. CAS: 78919-13-8
Synonyms: Ciloprost (Standard); ZK 36374 (Standard)
Referencia número: HY-B0190
No. CAS: 81525-10-2
Nafamostat, an anticoagulant, is a synthetic serine protease inhibitor. Nafamostat has anticancer and antivirus effect. Nafamostat induce apoptosis by up-regulating the expression of tumor necrosis factor receptor-1 (TNFR1). Nafamostat can be used in the development of the pathological thickening of the arterial wall .
Referencia número: HY-P2612A
Target:
Referencia número: HY-113081S1
Pureza: 98.77%
Referencia número: HY-168440
No. CAS: 2541626-73-5
Áreas de investigación:
Aurora-A ligand 1 is a high-affinity and specific Aurora-A inhibitor with a dissociation constant (Kd) value of 0.85 nM. Aurora-A ligand 1 can serve as a ligand for target protein (Ligands for Target Protein for PROTAC) for the development of PROTAC Aurora-A degraders with antitumor activity. Aurora-A ligand 1 can be used for the synthesis of HLB-0532259 (HY-168439). HLB-0532259 shows anti-tumor activity against neuroblastoma .
Referencia número: HY-W015273AR
No. CAS: 29953-71-7
Target:
Áreas de investigación:
2,4-Dimethoxybenzaldehyde is a tumor initiator with genotoxic property. 2,4-Dimethoxybenzaldehyde can induce benign papilloma development and converse to squamous cell carcinoma in the skin of susceptible mouse models. 2,4-Dimethoxybenzaldehyde can be used for skin cancer research .
Referencia número: HY-B0190AR
No. CAS: 82956-11-4
Synonyms: FUT-175 (Standard)
Nafamostat (mesylate) (Standard) is the analytical standard of Nafamostat (mesylate). This product is intended for research and analytical applications. Nafamostat mesylate (FUT-175), an anticoagulant, is a synthetic serine protease inhibitor. Nafamostat mesylate has anticancer and antivirus effect. Nafamostat mesylate induce apoptosis by up-regulating the expression of tumor necrosis factor receptor-1 (TNFR1). Nafamostat mesylate can be used in the development of the pathological thickening of the arterial wall .
Referencia número: HY-113081AS
Pureza: 98.05%
Referencia número: HY-128753S6
No. CAS: 288846-88-8
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
