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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
479 Results for "
Mevinolin-d9 (epimer mixture)
" in MedChemExpress (MCE) Product Catalog:
Products (479)
479 Results for "Mevinolin-d9 (epimer mixture)" in MCE Product Catalog:
Cat. No.: HY-W250306
CAS No.: 4197-24-4
Cat. No.: HY-W611263
CAS No.: 113816-36-7
Synonyms: MBTFP
Cat. No.: HY-W777599
CAS No.: 1216704-11-8
Synonyms: (Rac)-Naproxen-13C,d3-1
Target:
(±)-Naproxen- 13C,d3-1 ((Rac)-Naproxen- 13C,d3-1) is the deuterated, 13C-labeled (±)-Naproxen (HY-15029). (±)-Naproxen ((Rac)-Naproxen) is the racemate of Naproxen (HY-15030), consisting of R- and S-enantiomers. (±)-Naproxen binds to AKR1C3, which preferentially recognizes the R-enantiomer from the racemic mixture. It is used for AKR1C3 stereoselective ligand recognition and studies on NSAID binding mechanisms .
Cat. No.: HY-K1044
MCE Polymyxin B (1,000×), Sterile (50 mg/mL) is a filtered and sterilized antibiotic solution that can be used directly in cell culture. Polymixin B is a mixture of B1 and B2 polypeptides obtained from different strains of Bacillus polymyxa, with antibacterial activity against gram-negative bacteria. It can bind lipopolysaccharide (LPS) of the outer membrane of gram-negative bacteria and disrupts the cytoplasmic membrane by inducing large pores to allow nucleotide leakage in bacterial walls. This disrupts the permeability of the cytoplasmic membrane.
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Lactosylceramide (bovine buttermilk) (LacCer (bovine buttermilk)) is a natural lactosylceramide (LacCer) mixture derived from bovine buttermilk, belonging to neutral glycosphingolipids, and composed of a lactose polar head group and a ceramide backbone. LacCer is an important component of cell membrane glycosphingolipids and is associated with processes such as signal transduction, cell recognition, cell adhesion, and cell growth. LacCer derived from bovine buttermilk contains multiple molecular species composed of different long-chain bases and fatty acyl groups. Lactosylceramide (bovine buttermilk) can be used for research related to lactosylceramide and glycosphingolipids .
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Cat. No.: HY-B0428D
CAS No.: 130952-46-4
Synonyms: (E/Z)-OKY-046 sodium
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Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
(E/Z)-Ozagrel sodium [(E/Z)-OKY-046 sodium] is an EZ configuration mixture of Ozagrel sodium (HY-B0428A). Ozagrel sodium (OKY-046 sodium) is a high selective and orally active thromboxane A2 (TXA2) synthase inhibitor with an IC50 of 11 nM. Ozagrel sodium exerts anti-platelet aggregation, vasodilation and anti-inflammatory effects by inhibiting the production of TXA2 and increasing the production of prostacyclin (PGI2). Ozagrel sodium can be used for the study of ischemic stroke, asthma and thromboembolic diseases .
Cat. No.: HY-W011500R
CAS No.: 51805-45-9
Synonyms: Tris(2-carboxyethyl)phosphine hydrochloride (Standard)
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TCEP hydrochloride (Standard) is the analytical standard of TCEP hydrochloride (HY-W011500). This product is intended for research and analytical applications. TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a faster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively reduces protein disuldes without altering the properties or interacting with thiol-directed agents in the reaction mixture. TCEP hydrochloride is also a commonly used reducing agent in the DNA/AuNP chemistry .
Cat. No.: HY-W012908
CAS No.: 609-36-9
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DL-Proline is a racemic mixture of D-Proline and L-Proline, belonging to cyclic imino acids with a five-membered ring structure. DL-Proline serves as a key structural unit in peptide synthesis. DL-Proline stabilizes β-turn conformations and affects the secondary structure of peptide segments. DL-Proline exhibits biological activities such as regulating peptide segment conformations and enhancing cyclic peptide stability. DL-Proline can be used in research on diseases related to peptide structure and function, including cancer and bacterial infections .
Cat. No.: HY-L183
531 compounds
Pesticide is a single substance or mixture that can be used to prevent, mitigate, iminate pests or as a plant conditioner, defoliant or desiccant. In recent years, scientists have proposed the concept of "Molecules to Ecosystems", bringing the concept of molecular biology to understand the impact of pesticides, degradation and relationship with the environment or organisms. MCE integrates effective compounds approved as pesticides by agencies such as the Environmental Protection Agency (EPA), China Pesticide Information Network and some insecticidal compounds with potential for agricultural applications.
MCE can provide a library of 531 pesticide compounds that are tool compounds for relevant research.
Cat. No.: HY-101399SA
Synonyms: H-γ-Glu-Phe-OH-13C9,15N TFA; γ-Glutamylphenylalanine-13C9,15N TFA
Cat. No.: HY-118590A
CAS No.: 21416-68-2
Research Areas:
Infection Cardiovascular Disease Inflammation/Immunology Cancer
ICRF-196 is an racemic mixture of the (S,S)- and (R,R)-isomers of ICRF-193 (HY-118590). ICRF-193 is a DNA Topoisomerase II inhibitor. ICRF-193 can inhibit DNA syntheses and induces apoptosis. ICRF-193 exhibits anti-cancer and anti-inflammation effects. ICRF-193 shows cardioprotective effect against anthracycline toxicity to cardiomyocytes. ICRF-193 can be used for the researches of cancer, infection, inflammation and cardiovascular disease, such as acute promyelocytic leukemia .
Cat. No.: HY-167680
CAS No.: 483369-58-0
Synonyms: GSK823093
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Research Areas:
Denagliptin (GSK823093) is a small molecule dipeptidyl peptidase IV (DPP-4) inhibitor with activity for the suppression of endocrine and metabolic diseases. Denagliptin can be used to study type 2 diabetes. Denagliptin is stable in the solid state but degrades in solution and in mixtures with various excipients. Denagliptin also exhibits degradation in capsules, mainly through cyclization reactions to form (3S,7S,8aS) aminoamines to provide further synthetic materials. The degradation pathway of Denagliptin was elucidated, providing data to support its formulation development and regulatory filings .
Cat. No.: HY-173630A
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(R)-BMS-986449 is the racemic mixture of BMS-986449 (HY-173630). BMS-986449 is a CELMoD molecular glue and an IKZF2/IKZF4 degrader. BMS-986449 targets the degradation of transcription factors Helios (IKZF2) and Eos (IKZF4) in regulatory T (Treg) cells. BMS-986449 redirects the E3 ubiquitin ligase Cereblon to induce the degradation of Helios and Eos, reprogramming Treg cells and enhancing antitumor immunity. BMS-986449 is promising for research of advanced solid tumors .
Cat. No.: HY-N13772
CAS No.: 55812-91-4
Synonyms: (+)-Dihydroisorhamnetin
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Cat. No.: HY-W133898
CAS No.: 73049-73-7
Cat. No.: HY-W700621
CAS No.: 1189959-10-1
Synonyms: Tris(2-carboxyethyl)phosphine hydrochloride-d12
Cat. No.: HY-W747104
CAS No.: 52957-16-1
Category:
Target:
Synonyms: (±)-BAY-1251152; (±)-VIP152
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(±)-Enitociclib ((±)-BAY-1251152) is the racemic mixture of Enitociclib (HY-103019E). Enitociclib is a selective CDK9 inhibitor and apoptosis inducer. Enitociclib inhibits CDK9 activity and reduces the phosphorylation of Ser2 in the carboxyl-terminal domain (CTD) of RNA polymerase Pol II, thereby downregulating the transcription of key oncogenes such as MYC and MCL1. Enitociclib has anti-proliferative activity targeting MYC + lymphoma and multiple myeloma (MM) cells, and has synergistic effects with Bortezomib (HY-10227) and Lenalidomide (HY-A0003), and can be used in the research of hematological malignancies .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
