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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
476 Results for "
multifunctional
" in MedChemExpress (MCE) Product Catalog:
Products (476)
476 Results for "multifunctional" in MCE Product Catalog:
Art. -Nr.: HY-W115727A
CAS. Nr.: 9003-05-8
Synonyms: PAM,Anion,Mw 14-16 million
Art. -Nr.: HY-W115727B
CAS. Nr.: 9003-05-8
Synonyms: PAM,Anion,Mw 18 million
Art. -Nr.: HY-D1291
CAS. Nr.: 2255329-06-5
Art. -Nr.: HY-D1291A
CAS. Nr.: 2255329-07-6
Art. -Nr.: HY-P12114
Target:
Art. -Nr.: HY-N0657R
CAS. Nr.: 63902-38-5
Synonyms: Disodium sulfate, meets analytical specification of Ph. Eur. BP USP
Art. -Nr.: HY-W011725
CAS. Nr.: 2002-35-9
Synonyms: m6dA
Forschungsgebiete:
N-6-Methyl-2-deoxyadenosine (m6dA) is an adenine nucleoside analogue. N-6-Methyl-2-deoxyadenosine targets nuclear processes and DNA replication machineries including WER, SATB1, TFAM, Jumu, SSBP1, DNA polymerase η and phage polymerase Gp90 exo −. N-6-Methyl-2-deoxyadenosine acts as a multifunctional epigenetic regulator that modulates transcription, DNA damage response, cell cycle, transposon silencing, stress adaptation, epigenetic crosstalk, and nucleosome organization in both prokaryotes and eukaryotes. N-6-Methyl-2-deoxyadenosine regulates mitochondrial epigenetic inheritance and is required for fear extinction memory in mice. N-6-Methyl-2-deoxyadenosine exhibits dysregulated levels in cancers. N-6-Methyl-2-deoxyadenosine can be used for the research of glioblastoma, triple negative breast cancer, and conditioned fear (fear extinction impairment) .
Art. -Nr.: HY-N0113BR
CAS. Nr.: 6027-23-2
Synonyms: Ordenina hydrochloride (Standard); Peyocactine hydrochloride (Standard)
Category:
Coryphantha vivipara var arizonica Alkaloids Monophenols Cactaceae Other Alkaloids Phenols Plants
Target:
Reference Standards Bacterial p38 MAPK JNK ERK Akt Interleukin Related TNF Receptor NO Synthase COX Reactive Oxygen Species (ROS) Microphthalmia Associated Transcription Factor (MITF) Wnt β-catenin Dopamine Receptor Adrenergic Receptor 5-HT Receptor Serotonin Transporter Dopamine Transporter α-synuclein
Art. -Nr.: HY-N0113BS
Synonyms: Ordenina-d6 hydrochloride; Peyocactine-d6 hydrochloride
Target:
Isotope-Labeled Compounds Bacterial p38 MAPK JNK ERK Akt Interleukin Related TNF Receptor NO Synthase COX Reactive Oxygen Species (ROS) Microphthalmia Associated Transcription Factor (MITF) Wnt β-catenin Dopamine Receptor Adrenergic Receptor 5-HT Receptor Serotonin Transporter Dopamine Transporter α-synuclein
Forschungsgebiete:
Hordenine-d6 hydrochloride (Ordenina-d6 hydrochloride; Peyocactine-d6 hydrochloride) is the deuterated-labeled Hordenine hydrochloride (HY-N0113B). Hordenine hydrochloride (Ordenina hydrochloride; Peyocactine hydrochloride) is a multifunctional alkaloid with oral activity and blood-brain barrier penetration. Hordenine hydrochloride inhibits LPS-induced phosphorylation of p38, JNK, ERK1/2, p65, IκB, and AKT, prevents p65 nuclear translocation, and suppresses inflammatory cytokines and mediators. Hordenine hydrochloride inhibits melanin synthesis in melanocytes and reconstructed epidermis. Hordenine hydrochloride activates the Wnt/β-catenin signaling pathway. Hordenine hydrochloride activates DRD2, acts as a D3R partial agonist, α2A-AR full agonist, and 5-HT2A-R antagonist, and inhibits SERT and DAT. Hordenine hydrochloride inhibits α-synuclein accumulation and ameliorates motor deficits in Parkinson's disease models. Hordenine hydrochloride limits alcohol intake, reduces relapse drinking behavior. Hordenine hydrochloride can be used for research on mastitis, skin pigmentation, acute lung injury, foodborne diseases, hair loss, Parkinson's disease, bacterial infections, and alcohol use disorder .
Art. -Nr.: HY-P83719
Synonyms: DKFZp459C139 antibody;
EC 3.4.25.1 antibody;
LMPX antibody;
Macropain epsilon chain antibody;
MB1 antibody;
MGC104214 antibody;
MGC118075 antibody;
MGC134464 antibody;
Multicatalytic endopeptidase complex epsilon chain antibody;
Proteasome (prosome, macropain) subunit, beta type, 5 antibody;
Proteasome beta 5 subunit antibody;
Proteasome catalytic subunit 3 antibody;
Proteasome chain 6 antibody;
Proteasome epsilon chain antibody;
Proteasome subunit beta type-5 antibody;
Proteasome subunit MB1 antibody;
Proteasome subunit X antibody;
Proteasome subunit, beta type, 5 antibody;
Proteasome subunit, beta-5 antibody;
PSB5_HUMAN antibody;
PSMB5 antibody;
PSX large multifunctional protease X antibody;
X antibody
Art. -Nr.: HY-N0113A
CAS. Nr.: 62493-39-4
Synonyms: Ordenina sulfate; Peyocactine sulfate
Category:
Target:
Reference Standards Bacterial p38 MAPK JNK ERK Akt Interleukin Related TNF Receptor NO Synthase COX Reactive Oxygen Species (ROS) Microphthalmia Associated Transcription Factor (MITF) Wnt β-catenin Dopamine Receptor Adrenergic Receptor 5-HT Receptor Serotonin Transporter Dopamine Transporter α-synuclein
Art. -Nr.: HY-N0113S
CAS. Nr.: 1346598-66-0
Synonyms: Ordenina-d6; Peyocactine-d6
Target:
Isotope-Labeled Compounds Bacterial p38 MAPK JNK ERK Akt Interleukin Related TNF Receptor NO Synthase COX Reactive Oxygen Species (ROS) Microphthalmia Associated Transcription Factor (MITF) Wnt β-catenin Dopamine Receptor Adrenergic Receptor 5-HT Receptor Serotonin Transporter Dopamine Transporter α-synuclein
Hordenine-d6 (Ordenina-d6; Peyocactine-d6) is the deuterated-labeled Hordenine (HY-N0113). Hordenine (Ordenina; Peyocactine) is a multifunctional alkaloid with oral activity and blood-brain barrier penetration. Hordenine inhibits LPS-induced phosphorylation of p38, JNK, ERK1/2, p65, IκB, and AKT, prevents p65 nuclear translocation, and suppresses inflammatory cytokines and mediators. Hordenine promotes M2 macrophage polarization, restores blood-milk barrier integrity, alleviates oxidative stress by reducing ROS and MDA, and attenuates LPS-induced lung injury and pulmonary edema. Hordenine inhibits cAMP production, CREB phosphorylation, and MITF expression, thereby suppressing melanin synthesis in melanocytes and reconstructed epidermis. Hordenine activates the Wnt/β-catenin signaling pathway, promotes dermal papilla cell proliferation and hair shaft elongation, and accelerates hair regeneration. Hordenine activates DRD2, acts as a D3R partial agonist, α2A-AR full agonist, and 5-HT2A-R antagonist, and inhibits SERT and DAT. Hordenine inhibits α-synuclein accumulation and ameliorates motor deficits in Parkinson's disease models. Hordenine limits alcohol intake, reduces relapse drinking behavior, and modulates alcohol-induced conditioned place preference. Hordenine can be used for research on mastitis, skin pigmentation, acute lung injury, foodborne diseases, hair loss, Parkinson's disease, bacterial infections, and alcohol use disorder .
Art. -Nr.: HY-P703465
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TRMT112; AD-001; HSPC152; HSPC170; multifunctional methyltransferase subunit TRM112-like protein; tRNA methyltransferase 112 homolog; TRM112; HTrm112; TRMT11-2; TRNA Methyltransferase Activator Subunit 11-2; TRM112-Like Protein; TRNA Methyltransferase 11-2 Homolog; TRNA Methyltransferase 11-2 Homolog (S. Cerevisiae); TRNA Methyltransferase Subunit 11-2; HEMK2; N-6 Adenine-Specific DNA Methyltransferase 1 (Putative); Prev. C21orf127; Methylarsonite Methyltransferase N6AMT1; Prev. N6AMT1; Lysine N-Methyltransferase 9; PRED28; Methyltransferase N6AMT1; KMT9; Methyltransferase HEMK2; HemK Methyltransferase Family Member 2; M.HsaHemK2P; N6AMT; N-6 Adenine-Specific DNA Methyltransferase 1; MTQ2; Chromosome 21 Open Reading Frame 127; PrmC; N6-DNA-Methyltransferase; HemK Methyltransferase 2, ETF1 Glutamine And Histone H4 Lysine; Protein N(5)-Glutamine Methyltransferase
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
