476 Results for "

multifunctional

" in MedChemExpress (MCE) Product Catalog:
Products (476)

476 Results for "multifunctional" in MCE Product Catalog:

2
Gypenoside XLIX
Gypenoside XLIX
0 Images
2 Cited Publications
Cat. No.: HY-N1990
CAS No.: 94987-08-3
Category:  

Cardiovascular Disease Triterpenes Terpenoids Cucurbitaceae Plants Disease Research Fields Gynostemma pentaphyllum (Thunb.) Makino

Target:  

PPAR Sirtuin Keap1-Nrf2 Toll-like Receptor (TLR) NF-κB Reactive Oxygen Species (ROS) NOD-like Receptor (NLR) Apoptosis Pyroptosis Autophagy

Gypenoside XLIX is a multifunctional bioactive compound that can be isolated from Gynostemma pentaphyllum, with a Ka value of 1.58 μM for its binding to SIRT1. Gypenoside XLIX acts as a PPAR-α agonist. It inhibits the activation of TLR4-mediated NF-κB signaling pathway by activating the Sirt1/Nrf2 signaling pathway, reduces ROS accumulation, and alleviates hepatic inflammatory injury in mice with sepsis-induced liver disease. Gypenoside XLIX targets SIRT1 to block YAP-NLRP3 activation and improve sepsis-induced cardiomyopathy. Gypenoside XLIX inhibits apoptosis (Apoptosis), pyroptosis (Pyroptosis), autophagy (Autophagy), lipid peroxidation, pro-inflammatory cytokines and anti-inflammatory cytokines. Gypenoside XLIX alleviates sepsis-induced splenic injury by inhibiting inflammation and oxidative stress, and mitigates sepsis-associated encephalopathy by targeting PPAR-α. Gypenoside XLIX prevents acute kidney injury by inhibiting IGFBP7/IGF1R-mediated programmed cell death and inflammation. Gypenoside XLIX inhibits the expression and activity of vascular cell adhesion molecule-1 in cytokine-induced human endothelial cells. Gypenoside XLIX is applicable to research related to acute liver injury, lung injury, cardiomyopathy, acute splenic injury, sepsis-associated encephalopathy, acute kidney injury, atherosclerosis and chronic inflammation .
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Hordenine
Hordenine
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2 Cited Publications
Cat. No.: HY-N0113
CAS No.: 539-15-1
Synonyms: Ordenina; Peyocactine
Category:  

Cardiovascular Disease Alkaloids other families Monophenols Other Alkaloids Phenols Plants Disease Research Fields

Target:  

Bacterial p38 MAPK JNK ERK Akt Interleukin Related TNF Receptor NO Synthase COX Reactive Oxygen Species (ROS) Microphthalmia Associated Transcription Factor (MITF) Wnt β-catenin Dopamine Receptor Adrenergic Receptor 5-HT Receptor Serotonin Transporter Dopamine Transporter α-synuclein

Hordenine (Ordenina; Peyocactine) is a multifunctional alkaloid with oral activity and blood-brain barrier penetration. Hordenine inhibits LPS-induced phosphorylation of p38, JNK, ERK1/2, p65, IκB, and AKT, prevents p65 nuclear translocation, and suppresses inflammatory cytokines and mediators. Hordenine promotes M2 macrophage polarization, restores blood-milk barrier integrity, alleviates oxidative stress by reducing ROS and MDA, and attenuates LPS-induced lung injury and pulmonary edema. Hordenine inhibits cAMP production, CREB phosphorylation, and MITF expression, thereby suppressing melanin synthesis in melanocytes and reconstructed epidermis. Hordenine activates the Wnt/β-catenin signaling pathway, promotes dermal papilla cell proliferation and hair shaft elongation, and accelerates hair regeneration. Hordenine activates DRD2, acts as a D3R partial agonist, α2A-AR full agonist, and 5-HT2A-R antagonist, and inhibits SERT and DAT. Hordenine inhibits α-synuclein accumulation and ameliorates motor deficits in Parkinson's disease models. Hordenine limits alcohol intake, reduces relapse drinking behavior, and modulates alcohol-induced conditioned place preference. Hordenine can be used for research on mastitis, skin pigmentation, acute lung injury, foodborne diseases, hair loss, Parkinson's disease, bacterial infections, and alcohol use disorder .
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Hordenine hydrochloride
Hordenine hydrochloride
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2 Cited Publications
Cat. No.: HY-N0113B
CAS No.: 6027-23-2
Synonyms: Ordenina hydrochloride; Peyocactine hydrochloride
Category:  

Coryphantha vivipara var arizonica Alkaloids Monophenols Cactaceae Other Alkaloids Phenols Plants

Target:  

Bacterial p38 MAPK JNK ERK Akt Interleukin Related TNF Receptor NO Synthase COX Reactive Oxygen Species (ROS) Microphthalmia Associated Transcription Factor (MITF) Wnt β-catenin Dopamine Receptor Adrenergic Receptor 5-HT Receptor Serotonin Transporter Dopamine Transporter α-synuclein

Hordenine hydrochloride (Ordenina hydrochloride; Peyocactine hydrochloride) is a multifunctional alkaloid with oral activity and blood-brain barrier penetration. Hordenine hydrochloride inhibits LPS-induced phosphorylation of p38, JNK, ERK1/2, p65, IκB, and AKT, prevents p65 nuclear translocation, and suppresses inflammatory cytokines and mediators. Hordenine hydrochloride promotes M2 macrophage polarization, restores blood-milk barrier integrity, alleviates oxidative stress by reducing ROS and MDA, and attenuates LPS-induced lung injury and pulmonary edema. Hordenine hydrochloride inhibits cAMP production, CREB phosphorylation, and MITF expression, thereby suppressing melanin synthesis in melanocytes and reconstructed epidermis. Hordenine hydrochloride activates the Wnt/β-catenin signaling pathway, promotes dermal papilla cell proliferation and hair shaft elongation, and accelerates hair regeneration. Hordenine hydrochloride activates DRD2, acts as a D3R partial agonist, α2A-AR full agonist, and 5-HT2A-R antagonist, and inhibits SERT and DAT. Hordenine hydrochloride inhibits α-synuclein accumulation and ameliorates motor deficits in Parkinson's disease models. Hordenine hydrochloride limits alcohol intake, reduces relapse drinking behavior, and modulates alcohol-induced conditioned place preference. Hordenine hydrochloride can be used for research on mastitis, skin pigmentation, acute lung injury, foodborne diseases, hair loss, Parkinson's disease, bacterial infections, and alcohol use disorder .
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Melanin
Melanin
0 Images
1 Cited Publications
Cat. No.: HY-113485
CAS No.: 8049-97-6
Purity:  ≥99.0%
Category:  

Natural Products Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

Melanin is a unique pigment with myriad functions. It is multifunctional, providing defense against environmental stresses such as ultraviolet (UV) light, oxidizing agents and ionizing radiation.
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BNN6
BNN6
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1 Cited Publications
Cat. No.: HY-164117
CAS No.: 106476-75-9
Target:  

Reactive Oxygen Species (ROS) Apoptosis

Research Areas:  

Cancer

BNN6 is a thermoresponsive nitric oxide (NO) donor that often works by binding to a carrier. BNN6 decomposes under the heat stimulation generated by photothermal action, releasing high concentrations of NO, which exerts anti-tumor activity by inducing tumor cell apoptosis and inhibiting their repair. BNN6 can be used to synthesize the multifunctional biosensor BNN6-BiTiS3-iRGD, which exerts a synergistic anti-cancer effect with photothermal therapy (PTT) .
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Phenoxyacetic acid
Phenoxyacetic acid
0 Images
1 Cited Publications
Cat. No.: HY-Y0267
CAS No.: 122-59-8
Category:  

Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Insecticide Fungal Phytohormone

Phenoxyacetic acid is a multifunctional drug prodrug or auxin-type growth regulator, and its derivatives have insecticidal, herbicidal and antifungal activities .
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1
NCL Protein, Human (P.pastoris, His)
NCL Protein, Human (P.pastoris, His)
0 Images
1 Cited Publications
Cat. No.: HY-P71760
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NUCLEOLIN; Nsr1; Prev. NCL; Protein C23; Nucleolin; Nucleolin multifunctional Protein; C23; FLJ45706; MS1116 ; Nucl
Species:  
Human
Source:  
P. pastoris
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1
APE Protein, Human
APE Protein, Human
0 Images
1 Cited Publications
Cat. No.: HY-P7523
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: APEX1; APE1; Prev. APEX; DNA-(Apurinic Or Apyrimidinic Site) Endonuclease; APEN; APEX Nuclease; REF-1; APEX Nuclease (multifunctional DNA Repair Enzyme); REF1; Deoxyribonuclease (Apurinic Or Apyrimidinic); HAP1; Apurinic/Apyrimidinic (Abasic) Endonuclease
Species:  
Human
Source:  
E. coli
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Trimethyl chitosan
Trimethyl chitosan
0 Images
1 Cited Publications
Cat. No.: HY-148033
CAS No.: 52349-26-5
Synonyms: N,N,N-Trimethylchitosan
Trimethyl chitosan (N,N,N-Trimethylchitosan) is a multifunctional polymer and a derivative of Chitosan (HY-B2144A). Trimethyl chitosan targets the absorption enhancing proteins of tight junctions of intestinal and mucosal epithelial cells, induces tight junction protein rearrangement, and increases intercellular permeability. Trimethyl chitosan can stimulate the activity of promoting transmembrane transport of hydrophilic drugs (such as peptides and proteins) and can be used for drug delivery and synthesis of nanoparticles .
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Lactoferrin from Bovine milk
Lactoferrin from Bovine milk
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1 Cited Publications
Cat. No.: HY-P3161
CAS No.: 936541-36-5
Lactoferrin from Bovine milk is a substance released by neutrophils. Lactoferrin from Bovine milk is an orally active multifunctional iron binding glycoprotein. Lactoferrin from Bovine milk prevents cell adhesion, growth and spreading of cell colonies. Lactoferrin from Bovine milk also has antiviral activity and inhibits microbial and viral adhesion and entry into host cells. Besides, Lactoferrin from Bovine milk has anti-inflammatory, immunomodulatory, and anti-cancer activities .
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Acid Red 94 lactone
Acid Red 94 lactone
0 Images
1 Cited Publications
Cat. No.: HY-D0214A
CAS No.: 4159-77-7
Acid Red 94 lactone is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
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Withanone
Withanone
0 Images
1 Cited Publications
Cat. No.: HY-129692
CAS No.: 27570-38-3
Purity:  93.06%
Category:  

Withania somnifera Plants Solanaceae Steroids

Target:  

iGluR

Withanone is an active ingredient from the roots of Withania somnifera and a GRP75 inhibitor. Withanone has multifunctional neuroprotective effects in alleviating cognitive dysfunction. In neuron-like cells, Withanone can inhibit NMDA-induced excitotoxicity. Withanone can inhibit white adipose tissue browning by blocking the formation of the GRP75-ANT2-UCP1 complex, thereby alleviating cancer-related cachexia. Withanone can be used in the research of tumors and nervous system diseases .
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ALDH4A1 Protein, Human (sf9)
ALDH4A1 Protein, Human (sf9)
0 Images
1 Cited Publications
Cat. No.: HY-P76138
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ALDH4A1; Mitochondrial Delta-1-Pyrroline 5-Carboxylate Dehydrogenase; Prev. ALDH4; Aldehyde Dehydrogenase 4 Family, Member A1; L-Glutamate Gamma-Semialdehyde Dehydrogenase; Epididymis Secretory Sperm Binding Protein; P5CDh; multifunctional Fusion Protein
Species:  
Human
Source:  
Sf9 insect cells
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AF488 NHS ester diTEA
AF488 NHS ester diTEA
0 Images
1 Cited Publications
Cat. No.: HY-D1223
AF488 NHS ester diTEA is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
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IL-1 beta Protein, Pig
IL-1 beta Protein, Pig
0 Images
1 Cited Publications
Cat. No.: HY-P7206
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; Interleukin 1 Beta; multifunctional Fusion Protein; IL1F2; Pro-Interleukin-1-Beta; Interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; Interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Pig
Source:  
E. coli
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IL-1 beta Protein, Human (solution)
IL-1 beta Protein, Human (solution)
0 Images
1 Cited Publications
Cat. No.: HY-P70586
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; Interleukin 1 Beta; multifunctional Fusion Protein; IL1F2; Pro-Interleukin-1-Beta; Interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; Interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Human
Source:  
E. coli
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IL-1 beta Protein, Rabbit
IL-1 beta Protein, Rabbit
0 Images
1 Cited Publications
Cat. No.: HY-P73150
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; Interleukin 1 Beta; multifunctional Fusion Protein; IL1F2; Pro-Interleukin-1-Beta; Interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; Interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Rabbit
Source:  
E. coli
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Animal-Free IL-1 beta Protein, Mouse (His)
Animal-Free IL-1 beta Protein, Mouse (His)
0 Images
1 Cited Publications
Cat. No.: HY-P700187AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; Interleukin 1 Beta; multifunctional Fusion Protein; IL1F2; Pro-Interleukin-1-Beta; Interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; Interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Mouse
Source:  
E. coli
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IL-1 beta Protein, Human (N-His)
IL-1 beta Protein, Human (N-His)
0 Images
1 Cited Publications
Cat. No.: HY-P700254
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; Interleukin 1 Beta; multifunctional Fusion Protein; IL1F2; Pro-Interleukin-1-Beta; Interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; Interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Human
Source:  
E. coli
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IL-1 beta Protein, Canine (Tag free)
IL-1 beta Protein, Canine (Tag free)
0 Images
1 Cited Publications
Cat. No.: HY-P73146A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1B; IL-1B; Interleukin 1 Beta; multifunctional Fusion Protein; IL1F2; Pro-Interleukin-1-Beta; Interleukin-1 Beta; Preinterleukin 1 Beta; IL1-BETA; Interleukin 1beta; IL-1 Beta; IL1beta; Catabolin; IL-1
Species:  
Canine
Source:  
E. coli
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