106476-75-9
Chemical Structure
BNN6
- CAS. Nr.: 106476-75-9
- Formula:C14H22N4O2
- Molecular Weight:278.35
InChIKey: YLTBEWSTQZLPJS-UHFFFAOYSA-N
SMILES: O=NN(C(C)CC)C1=CC=C(N(C(C)CC)N=O)C=C1
Biological Activity: BNN6 is a thermoresponsive nitric oxide (NO) donor that often works by binding to a carrier. BNN6 decomposes under the heat stimulation generated by photothermal action, releasing high concentrations of NO, which exerts anti-tumor activity by inducing tumor cell apoptosis and inhibiting their repair. BNN6 can be used to synthesize the multifunctional biosensor BNN6-BiTiS3-iRGD, which exerts a synergistic anti-cancer effect with photothermal therapy (PTT)[1][2][3].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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BNN6 | 98.0% | BNN6 is a thermoresponsive nitric oxide (NO) donor that often works by binding to a carrier. BNN6 decomposes under the heat stimulation generated by photothermal action, releasing high concentrations of NO, which exerts anti-tumor activity by inducing tumor cell apoptosis and inhibiting their repair. BNN6 can be used to synthesize the multifunctional biosensor BNN6-BiTiS3-iRGD, which exerts a synergistic anti-cancer effect with photothermal therapy (PTT). | ||||||||||||||||||||
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- [1]. Jiang M, et al., BiTiS3 bio-transducer with explosive on-demand generation of NO gas for synergetic cancer therapy. Biosens Bioelectron. 2024 Feb 15;246:115895. [Content Brief]
- [2]. Yang J, et al. Controlled Nitric Oxide-Releasing Nanovehicles for Enhanced Infected Wound Healing: A Study on PDA@BNN6 Encapsulated in GelMA Hydrogel. Int J Nanomedicine. 2024 Nov 8;19:11499-11516. [Content Brief]
Keywords
