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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
150 Results for "
2D6
" in MedChemExpress (MCE) Product Catalog:
Products (150)
150 Results for "2D6" in MCE Product Catalog:
Cat. No.: HY-113739A
CAS No.: 144025-14-9
Synonyms: (S)-DCIT
Target:
Research Areas:
(S)-Desmethylcitalopram is the isomer of Desmethylcitalopram hydrochloride (HY-113739). Desmethylcitalopram (DCIT) hydrochloride is the active metabolite of Citalopram (HY-121203). Desmethylcitalopram has antidepressant effects. Desmethylcitalopram also inhibits cytochrome P450-2D6，-2C19 with IC50s of 39.5 and 53.5 μM .
Cat. No.: HY-131630
CAS No.: 62572-94-5
Target:
Research Areas:
O-Desmethylmetoprolol is the metabolite of Metoprolol (HY-17503) produced by CYP2D6 enzyme metabolism .
Cat. No.: HY-144286
CAS No.: 2761009-43-0
CXCR4 antagonist 3 (compound 12a) is a potent antagonist of CXCR4 with an IC50 of 11 nM. CXCR4 antagonist 3 is a congener of TIQ15. CXCR4 antagonist 3 demonstrates the best overall properties including CXCR4 antagonism, CYP 2D6 inhibition, metabolic stability, and permeability. CXCR4 antagonist 3 has the potential for the research of human immunodeficiency virus .
Cat. No.: HY-N3090
CAS No.: 46992-81-8
Target:
Cat. No.: HY-B0352A
CAS No.: 61337-87-9
Synonyms: (S)-Org3770; (S)-6-Azamianserin
Target:
Research Areas:
(S)-Mirtazapine ((S)-Org3770) is a S(+)-enantiomer of Mirtazapine with pronociceptive properties in an animal model of acute thermal nociception. (S)-Mirtazapine is a stereoselective 5-HT2 receptor antagonist. (S)-Mirtazapine is metabolized by CYP2D6 and CYP1A2 .
Cat. No.: HY-18569AR
CAS No.: 6505-45-9
Synonyms: Indole-3-acetic acid sodium (Standard); 3-IAA sodium (Standard)
Cat. No.: HY-113739S1
Synonyms: DCIT-d4 hydrochloride
Target:
Research Areas:
Promethazine sulfoxide is a metabolite of the histamine H1 receptor antagonist Promethazine (HY-B1296). It is formed from promethazine by the cytochrome P450 (CYP) isoform CYP2D6.
Cat. No.: HY-146177
CAS No.: 2531281-25-9
Target:
Research Areas:
CYP3A4 enzyme-IN-1 (compound 59) is a potent antibacterial agent, with a MIC of 1 μg/mL for MRSA. CYP3A4 enzyme-IN-1 exhibits low to moderate inhibitory effects on CYP1A2, CYP2E1, CYP2D6, and CYP3A4 enzymes .
Cat. No.: HY-16718A
CAS No.: 1044535-61-6
Synonyms: PF-00251802 hydrochloride
Research Areas:
Dagrocorat (PF-00251802) hydrochloride is an orally active and selective high-affinity partial agonist of the glucocorticoid receptor. Dagrocorat hydrochloride is also a time-dependent reversible inhibitor of CYP3A (IC50=1.3 μM in human liver microsomes) and CYP2D6 (Ki=0.57 μM in human liver microsomes). Dagrocorat hydrochloride can be used for the research of rheumatoid arthritis .
Cat. No.: HY-111906
CAS No.: 1222509-12-7
Target:
Research Areas:
SCYX-6759 is an orally active, blood-brain barrier permeable anti-T. brucei agent. SCYX-6759 inhibits cytochrome P450 (IC50s: 30.3, 30.6, 47.4 μM for 2D6, 2C9, 2C19, respectively.) SCYX-6759 exhibits potent activity against T. b. brucei 427, T. b. rhodesiense STIB900, and T. b. gambiense STIB930, with IC50s of 0.07, 0.038 and 0.030 μg/mL, respectively .
Cat. No.: HY-178479
CAS No.: 2581050-29-3
Research Areas:
IDO1-IN-30 (Compound (R)-100) is a potent and highly selective IDO1 inhibitor. IDO1-IN-30 has an IC50 of 4.8 nM to IDO1 in SKOV3 cells. IDO1-IN-30 does not show significant cytotoxicity at 25 µM in HepG2 cells. IDO1-IN-30 can eliminate inhibition of CYP450 enzymes (such as 3A4, 2C9, 2D6). IDO1-IN-30 can be used for research on cancer and inflammatory conditions .
Cat. No.: HY-B1912S1
Cat. No.: HY-132644S1
Cat. No.: HY-144150S
Cat. No.: HY-W702303
Cat. No.: HY-143943S
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
