O-Desmethylmetoprolol
Based on 1 Customer Validation
O-Desmethylmetoprolol is the metabolite of Metoprolol (HY-17503) produced by CYP2D6 enzyme metabolism.
For research use only. We do not sell to patients.
- Purity: 98.66%
- CAS No.: 62572-94-5
- Formula: C14H23NO3
- Molecular Weight:253.34
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Metabolism/Protease Compound Library
HY-L012
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Drug Metabolite Library
HY-L098
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Human Metabolite Library
HY-L123
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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High-Throughput Bioactive Compound Library
HY-L205
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Mass Spectrometry Human Metabolite Library
HY-L215
Biological Activity
Chemical Information
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CAS No. 62572-94-5
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Appearance Solid
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Molecular Weight 253.34
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Formula C14H23NO3
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Color White to off-white
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SMILES
OCCC1=CC=C(OCC(O)CNC(C)C)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (394.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (622 KB)
- English - EN (622 KB)
- Français - FR (622 KB)
- Deutsch - DE (622 KB)
- Norwegian - NO (622 KB)
- Español - ES (622 KB)
- Swedish - SV (622 KB)
- Italian - IT (622 KB)
- Korean - KR (622 KB)
- Portuguese - PT (622 KB)
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Handling Instructions (2659 KB)
References
[1]. Bae SH, et al., Simultaneous determination of metoprolol and its metabolites, α-hydroxymetoprolol and O-desmethylmetoprolol, in human plasma by liquid chromatography with tandem mass spectrometry: Application to the pharmacokinetics of metoprolol associated with CYP2D6 genotypes. J Sep Sci. 2014 Jun;37(11):1256-64. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9473 mL | 19.7363 mL | 39.4726 mL | 98.6816 mL |
| 5 mM | 0.7895 mL | 3.9473 mL | 7.8945 mL | 19.7363 mL | |
| 10 mM | 0.3947 mL | 1.9736 mL | 3.9473 mL | 9.8682 mL | |
| 15 mM | 0.2632 mL | 1.3158 mL | 2.6315 mL | 6.5788 mL | |
| 20 mM | 0.1974 mL | 0.9868 mL | 1.9736 mL | 4.9341 mL | |
| 25 mM | 0.1579 mL | 0.7895 mL | 1.5789 mL | 3.9473 mL | |
| 30 mM | 0.1316 mL | 0.6579 mL | 1.3158 mL | 3.2894 mL | |
| 40 mM | 0.0987 mL | 0.4934 mL | 0.9868 mL | 2.4670 mL | |
| 50 mM | 0.0789 mL | 0.3947 mL | 0.7895 mL | 1.9736 mL | |
| 60 mM | 0.0658 mL | 0.3289 mL | 0.6579 mL | 1.6447 mL | |
| 80 mM | 0.0493 mL | 0.2467 mL | 0.4934 mL | 1.2335 mL | |
| 100 mM | 0.0395 mL | 0.1974 mL | 0.3947 mL | 0.9868 mL |
O-Desmethylmetoprolol Related Classifications
HY-131630 Related Classifications
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