2. Metabolic Enzyme/Protease
  3. Indoleamine 2,3-Dioxygenase (IDO) Cytochrome P450
  4. IDO1-IN-30

IDO1-IN-30 (Compound (R)-100) is a potent and highly selective IDO1 inhibitor. IDO1-IN-30 has an IC50 of 4.8 nM to IDO1 in SKOV3 cells. IDO1-IN-30 does not show significant cytotoxicity at 25 µM in HepG2 cells. IDO1-IN-30 can eliminate inhibition of CYP450 enzymes (such as 3A4, 2C9, 2D6). IDO1-IN-30 can be used for research on cancer and inflammatory conditions.

For research use only. We do not sell to patients.

IDO1-IN-30

IDO1-IN-30 Chemical Structure

CAS No. : 2581050-29-3

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Other Forms of IDO1-IN-30:

IDO1-IN-30 Related Antibodies

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View All Indoleamine 2,3-Dioxygenase (IDO) Isoform Specific Products:

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IDO1 IDO2 IDO

View All Cytochrome P450 Isoform Specific Products:

View All Isoforms
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A CYP3A4 CYP17A1

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Description

IDO1-IN-30 (Compound (R)-100) is a potent and highly selective IDO1 inhibitor. IDO1-IN-30 has an IC50 of 4.8 nM to IDO1 in SKOV3 cells. IDO1-IN-30 does not show significant cytotoxicity at 25 µM in HepG2 cells. IDO1-IN-30 can eliminate inhibition of CYP450 enzymes (such as 3A4, 2C9, 2D6). IDO1-IN-30 can be used for research on cancer and inflammatory conditions[1].

Molecular Weight

398.37

Formula

C19H16F2N6O2
CAS No.
SMILES

FC1=C(OC)C=C(F)C(N2N=NC([C@H](O)C3=C(N=CC4=CN=CN34)C5CC5)=C2)=C1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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IDO1-IN-30 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IDO1-IN-302581050-29-3Indoleamine 2,3-Dioxygenase (IDO)Cytochrome P450CYPsIDO1SKOV3HepG2CYP450cancerinflammationInhibitorinhibitorinhibit

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