Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
150 Results for "
2D6
" in MedChemExpress (MCE) Product Catalog:
Products (150)
150 Results for "2D6" in MCE Product Catalog:
Cat. No.: HY-RS03461
Target:
Research Areas:
CYP2D6 Human Pre-designed siRNA Set A contains three designed siRNAs for CYP2D6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-E72100
Target:
Research Areas:
Human CYP2D6, Reductase+b5 refers to a near-physiological recombinant microsomal system co-expressed in insect cells, consisting of human cytochrome P450 2D6, NADPH-P450 oxidoreductase (CPR) and cytochrome b5. Human CYP2D6 is a human cytochrome P450 subtype belonging to the CYP2 family, and also serves as a major metabolic enzyme capable of crossing the blood-brain barrier. Its expression is centered in the human liver (also detected in the brain) and exhibits high polymorphism .
Cat. No.: HY-10466S1
Synonyms: BMS-790052-13C2,d6; EBP 883-13C2,d6
Cat. No.: HY-143683S
CAS No.: 1782458-84-7
Synonyms: 1,3-Dimethylxanthine-13C2,d6; Theo-24-13C2,d6
Cat. No.: HY-W025785S1
Synonyms: Solvent Yellow 2-d6; Dimethyl yellow-d6
Cat. No.: HY-32348S1
Synonyms: 1.alpha.-Hydroxyvitamin D2-d6
Target:
Research Areas:
Saccharolactone is a potent orally active β-glucuronidase inhibitor. Saccharolactone markedly lowers biliary endogenous β-glucuronidase activity in the rat bile. Saccharolactone can stabilize glucuronide metabolites in vitro. Saccharolactone is also a strong inhibitor of CYP1A2, 2D6, 3A4 and 2C8 isoforms (IC50 < 4 mM) .
Cat. No.: HY-N1483A
CAS No.: 618094-85-2
Target:
Synonyms: (-)-Cephaeline dihydrochloride (Standard); NSC 32944 (Standard)
Target:
Cat. No.: HY-N2425R
CAS No.: 86831-54-1
Cat. No.: HY-181747
Target:
Research Areas:
CYP11A1-IN-3 (Compound II-4) is a selective CYP11A1 inhibitor with an IC50 of 26.7 nM. CYP11A1-IN-3 shows selectivity towards CYP1A2, 2C9 and 2D6. CYP11A1-IN-3 can be used for the research of castration-resistant prostate cancer .
Cat. No.: HY-W740630
CAS No.: 102335-57-9
Target:
Research Areas:
8-Hydroxy mirtazapine is a metabolite of the antidepressant Mirtazapine (HY-B0352). 8-Hydroxy mirtazapine is formed from mMirtazapine by the cytochrome P450 (CYP) isoform CYP2D6.
Cat. No.: HY-Z2493
CAS No.: 573691-09-5
Target:
Research Areas:
Aripiprazole N-oxide is a metabolite of the atypical antipsychotic Aripiprazole (HY-14546). Aripiprazole N-oxide is formed from aripiprazole by the cytochrome P450 (CYP) isoforms CYP2D6 and CYP3A4.
Cat. No.: HY-181662
CAS No.: 883012-32-6
Target:
Research Areas:
DLK-IN-2 is a selective inhibitor of DLK and neuroprotective agent. DLK-IN-2 shows no significant inhibition against CYPs 3A4, 2D6 and 2C9. DLK-IN-2 inhibits acute axonal palmitoylation of DLK, blocks DLK-dependent pro-degenerative axon-to-soma retrograde signaling and suppresses c-Jun phosphorylation. DLK-IN-2 can be used for the mechanistic study of neurodegenerative diseases .
Cat. No.: HY-184883
CAS No.: 2746405-41-2
Target:
Research Areas:
VU6035406 is a functionally selective mAChR inhibitor, with mAChR IC50 values of 21 nM, 51 nM and 47 nM against human, rat and mouse targets, respectively. VU6035406 does not act as a P-glycoprotein substrate. VU6035406 shows extremely low inhibitory activity against cytochrome P450 1A2, 2C9, 2D6 and 3A4. VU6035406 can be used in the research of neurological and psychiatric disorders .
Cat. No.: HY-113575
CAS No.: 1008531-60-9
Synonyms: OPC-14857 hydrochloride; DM-14857 hydrochloride
Target:
Research Areas:
Dehydroaripiprazole (OPC-14857) hydrochloride is an active metabolite of Aripiprazole. Aripiprazole is an antipsychotic agent and is metabolized by CYP3A4 and CYP2D6 forming mainly Dehydroaripiprazole hydrochloride. Dehydroaripiprazole hydrochloride has with antipsychotic activity equivalent to Aripiprazole .
Cat. No.: HY-W702646
CAS No.: 352233-14-8
Target:
Research Areas:
Hydroxymethyl tolperisone hydrochloride is a metabolite of Tolperisone (HY-B1139A). Hydroxymethyl tolperisone hydrochloride is formed from tolperisone primarily by the cytochrome P450 (CYP) isoform CYP2D6 and to a lesser extent by CYP2C19 and CYP1A2.
Cat. No.: HY-W803860
CAS No.: 86383-21-3
Target:
Research Areas:
N-Depropylpropafenone is an active metabolite of Propafenone (HY-B0432), generated through the CYP450 enzyme system (mainly CYP2D6). It functions by blocking sodium ion channels, slowing myocardial conduction and exhibiting certain antiarrhythmic effects .
Cat. No.: HY-105124AR
CAS No.: 60398-91-6
Synonyms: Ro 3-4787 hydrochloride (Standard)
Research Areas:
Bufuralol (hydrochloride) (Standard) is the analytical standard of Bufuralol (hydrochloride). This product is intended for research and analytical applications. Bufuralol (Ro 3-4787) hydrochloride is a potent non-selective, orally active β-adrenoreceptor antagonist with partial agonist activity. Bufuralol hydrochloride is a CYP2D6 probe substrate .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
