Dehydroaripiprazole hydrochloride
Based on 1 publication(s) in Google Scholar
Dehydroaripiprazole (OPC-14857) hydrochloride is an active metabolite of Aripiprazole. Aripiprazole is an antipsychotic agent and is metabolized by CYP3A4 and CYP2D6 forming mainly Dehydroaripiprazole hydrochloride. Dehydroaripiprazole hydrochloride has with antipsychotic activity equivalent to Aripiprazole.
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- CAS No.: 1008531-60-9
- Formule: C23H26Cl3N3O2
- Masse moléculaire:482.83
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Dehydroaripiprazole hydrochloride
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Activité biologique
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5-HT1A Receptor 4.2 nM (Ki) |
Chemical Information
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CAS No. 1008531-60-9
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Masse moléculaire 482.83
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Formule C23H26Cl3N3O2
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SMILES
O=C1NC2=C(C=CC(OCCCCN3CCN(C4=CC=CC(Cl)=C4Cl)CC3)=C2)C=C1.Cl
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Synonyms
OPC-14857 hydrochloride; DM-14857 hydrochloride
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Korean J Physiol Pharmacol
2020 Nov 1;24(6):545-553. PMID: 33093275
Pureté et documentation
Références
[1]. Kirschbaum KM, et al. Serum levels of aripiprazole and dehydroaripiprazole, clinical response and side effects. World J Biol Psychiatry. 2008;9(3):212-8. [Content Brief]
[2]. Lin SK, et al. Aripiprazole and dehydroaripiprazole plasma concentrations and clinical responses in patients with schizophrenia. J Clin Psychopharmacol. 2011 Dec;31(6):758-62. [Content Brief]
[4]. Stip E, Tourjman V. et al. Aripiprazole in schizophrenia and schizoaffective disorder: A review. Clin Ther. 2010;32 Suppl 1:S3-20. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)