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Cat. No.: HY-113575

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Dehydroaripiprazole hydrochloride

(Synonyms: OPC-14857 hydrochloride; DM-14857 hydrochloride)

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

Dehydroaripiprazole (OPC-14857) hydrochloride is an active metabolite of Aripiprazole. Aripiprazole is an antipsychotic agent and is metabolized by CYP3A4 and CYP2D6 forming mainly Dehydroaripiprazole hydrochloride. Dehydroaripiprazole hydrochloride has with antipsychotic activity equivalent to Aripiprazole.

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CAS No.: 1008531-60-9
Formule: C₂₃H₂₆Cl₃N₃O₂
Masse moléculaire:482.83

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Dehydroaripiprazole hydrochloride Chemical Structure

CAS No.: 1008531-60-9

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Chemical Information
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Description

IC₅₀ & Target^[4]

5-HT_1A Receptor

4.2 nM (Ki)

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Chemical Information

CAS No. 1008531-60-9
Masse moléculaire 482.83
Formule C₂₃H₂₆Cl₃N₃O₂
SMILES

O=C1NC2=C(C=CC(OCCCCN3CCN(C4=CC=CC(Cl)=C4Cl)CC3)=C2)C=C1.Cl
Synonyms

OPC-14857 hydrochloride; DM-14857 hydrochloride
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Korean J Physiol Pharmacol

Open channel block of Kv1.4 potassium channels by aripiprazole. [Abstract]

2020 Nov 1;24(6):545-553. PMID: 33093275

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Kirschbaum KM, et al. Serum levels of aripiprazole and dehydroaripiprazole, clinical response and side effects. World J Biol Psychiatry. 2008;9(3):212-8. [Content Brief]

[2]. Lin SK, et al. Aripiprazole and dehydroaripiprazole plasma concentrations and clinical responses in patients with schizophrenia. J Clin Psychopharmacol. 2011 Dec;31(6):758-62. [Content Brief]

[3]. Hui-ChingHuang, et al. Detection and quantification of aripiprazole and its metabolite, dehydroaripiprazole, by gas chromatography–mass spectrometry in blood samples of psychiatric patients. Journal of Chromatography B. Volume 856, Issues 1-2, 1 September 2007, Pages 57-61.

[4]. Stip E, Tourjman V. et al. Aripiprazole in schizophrenia and schizoaffective disorder: A review. Clin Ther. 2010;32 Suppl 1:S3-20. [Content Brief]

Calculators

Calculateur de molarité

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Dehydroaripiprazole hydrochloride

1 Cited Publications

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Dehydroaripiprazole hydrochloride

Publications Citing Use of MedChemExpress (MCE) Dehydroaripiprazole hydrochloride

Voir tous les produits spécifiques à Isoform 5-HT Receptor

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Publications (1)

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Dehydroaripiprazole hydrochloride Related Classifications

HY-113575 Related Classifications