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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
67 Results for "
CPPs
" in MedChemExpress (MCE) Product Catalog:
Products (67)
67 Results for "CPPs" in MCE Product Catalog:
Cat. No.: HY-16658BG
CAS No.: 161401-82-7
Cat. No.: HY-W110242
CAS No.: 41998-38-3
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(S)-CPP is an allosteric BDK inhibitor. (S)-CPP can be used in the research of type 2 diabetes .
Cat. No.: HY-RS16324
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CPP Human Pre-designed siRNA Set A contains three designed siRNAs for CPP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P1324A
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Cat. No.: HY-W110242A
CAS No.: 194979-70-9
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(S)-CPP sodium serves as an inhibitor of the branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, commonly referred to as BDK or keto acid dehydrogenase kinase. As a negative regulator of BCKDC activity, the inhibition of BDK by (S)-CPP (with an IC50 of 6.3 μM) results in the activation of the complex and a notable decrease in plasma levels of leucine/isoleucine and valine in wild-type mice.
Cat. No.: HY-P5936
CAS No.: 201608-15-3
Synonyms: DEVD-CHO-CPP 32
Cat. No.: HY-P4081
CAS No.: 350495-34-0
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Cat. No.: HY-P2193A
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Cat. No.: HY-111280
CAS No.: 854924-64-4
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ST 198 is an orally active D3R antagonist. ST 198 can block the expression of nicotine-induced CPP at doses selective for D3R. ST 198 can be used for the research of neurological disease .
Cat. No.: HY-P3234
CAS No.: 191338-87-1
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Cat. No.: HY-P4135
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Cat. No.: HY-P4139
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Cat. No.: HY-101324AR
CAS No.: 61655-58-1
Synonyms: CPP monohydrochloride (Standard)
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MK-212 (monohydrochloride) (Standard) is the analytical standard of MK-212 (monohydrochloride). This product is intended for research and analytical applications. MK-212 monohydrochloride (CPP monohydrochloride) is an orally active, blood-brain barrier permeable agonist of 5-HT1C, 5-HT2 and 5-HT1A receptors. MK-212 monohydrochloride induces hyperthermia, nausea, arousal, irritability and restlessness, inhibits the elevation of plasma cortisol and prolactin, and reduces feelings of calmness and overall positive affect. MK-212 monohydrochloride mediates anxiety-like behaviors and motor inhibition. MK-212 monohydrochloride is applicable to research related to schizophrenia and anxiety disorders .
Cat. No.: HY-187176
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CPP-13 is a selective PARP1 PROTAC degrader with a DC50 of 0.48 nM. CPP-13 induces CRBN-dependent ubiquitination and proteasomal degradation of PARP1. CPP-13 induces DNA damage. CPP-13 inhibits the growth of BRCA-deficient breast cancer and pancreatic cancer. CPP-13 can be used in studies related to BRCA-deficient breast cancer and BRCA-deficient pancreatic cancer .
Cat. No.: HY-W1025152
CAS No.: 760947-97-5
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CPP-115 hydrochloride is an orally active, selective GABA-AT inhibitor with a Ki value of 9.7 μM. CPP-115 hydrochloride blocks GABA degradation and increases GABA levels in the brain. CPP-115 hydrochloride does not bind to GABA transporters, does not displace GABA from GABAA/GABAB receptors, and does not act as an agonist/antagonist of GABAC receptors. CPP-115 hydrochloride reduces cocaine-induced dopamine release, blocks cocaine-induced conditioned place preference, and suppresses seizure activity in a rat model of infantile spasms. CPP-115 hydrochloride can be used in research related to infantile spasms and epilepsy .
Cat. No.: HY-P11841
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Cat. No.: HY-P11792
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Cat. No.: HY-P11856
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Cat. No.: HY-P11925
CAS No.: 934965-51-2
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CPP44 is a tumor lineage-homing cell-penetrating peptide (CPP) that selectively enters myeloid leukemia cells and liver tumor cells. The cellular internalization of CPP44 is associated with M160 (CD163L1), and it mainly enters cells via an ATP- and dynein-dependent, clathrin-independent endocytic pathway. CPP44 can be used in studies related to acute myeloid leukemia, hepatocellular carcinoma, tumor-targeted delivery, and tumor imaging .
Cat. No.: HY-P11926
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Cys-CPP44 is a cell-penetrating peptide with a Cys introduced at the N-terminus, which can specifically penetrate hepatocellular carcinoma cells. Modification with Cys-CPP44 promotes the specific penetration of arsenic trioxide-loaded liposomes into hepatocellular carcinoma cells and enhances the cellular uptake of liposomes by these cells. Cys-CPP44 can be used for the research of hepatocellular carcinoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
