Ac-ESMD-CHO
Ac-ESMD-CHO is an inhibitor of caspase-3 and caspase-7. Ac-ESMD-CHO inhibits proteolytic cleavage of the caspase-3 precursor peptide (CPP32) at the Glu-Ser-Met-Asp (ESMD) site.
For research use only. We do not sell to patients.
- CAS No.: 191338-87-1
- Formula: C19H30N4O10S
- Molecular Weight:506.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 191338-87-1
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Molecular Weight 506.53
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Formula C19H30N4O10S
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Sequence
Ac-Glu-Ser-Met-Asp-CHO
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Sequence Shortening
Ac-ESMD-CHO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Hayashida M, et al. Cell death induction by CTL: perforin/granzyme B system dominantly acts for cell death induction in human hepatocellular carcinoma cells. Proc Soc Exp Biol Med. 2000 Nov;225(2):143-50. [Content Brief]
[2]. Agniswamy J, et al. Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis. FEBS J. 2007 Sep;274(18):4752-65. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)