174 Results for "

Choline

" in MedChemExpress (MCE) Product Catalog:
Products (174)

174 Results for "Choline" in MCE Product Catalog:

Cat. No.: HY-W100403
CAS No.: 55357-38-5
Synonyms: Choline p-toluenesulfonate
Choline tosylate (Choline p-toluenesulfonate) is an intermediate and also a substrate of choline acetyltransferase (CHAT). Choline tosylate inhibits phospholipase A2 and phospholipase C .
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Cat. No.: HY-P2812A
CAS No.: 9001-87-0
Target:  

Phospholipase

Research Areas:  

Cardiovascular Disease Cancer

Phospholipase D, peanut is a phospholipase D (EC 3.1.4.4) of the PLD superfamily found in peanuts, acting as a phosphodiesterase and signaling enzyme with activity toward phosphatidylcholine. Phospholipase D hydrolyzes phosphatidylcholine to phosphatidic acid and choline, and catalyzes transphosphatidylation reactions. Phospholipase D can be used for the research of myocardial disease, ischemic heart disease, congestive heart failure, diabetic cardiomyopathy, cardiac hypertrophy, vascular abnormalities, breast cancer, gastric cancer, renal cancer, colorectal cancer .
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Cat. No.: HY-100045
CAS No.: 21064-69-7
Synonyms: 4-NitrophenylphosphorylCholine; 4-NitrophenylphosphorylCholine; O-(4-Nitrophenylphosphoryl)Choline
p-Nitrophenyl phosphorylcholine (4-Nitrophenylphosphorylcholine) is a chromogenic Phospholipase C substrate. Phospholipase C hydrolyzes p-Nitrophenyl phosphorylcholine to release p-nitrophenol, a yellow chromophore. p-Nitrophenyl phosphorylcholine is used to determine the phospholipase C production of Pseudomonas aeruginosa. It also applies to studies related to Pseudomonas aeruginosa infection .
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Cat. No.: HY-P2743
CAS No.: 9028-67-5
Research Areas:  

Others

Choline oxidase (EC 1.1.3.17) catalyzes the oxidation of choline to glycine betaine via betaine aldehyde in glycine betaine biosynthesis and betaine acts as an osmolyte. Choline oxidase has potential in enzymatic betaine production .
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Cat. No.: HY-W039760
CAS No.: 17773-10-3
2-Hydroxy-N,N,N-trimethylethan-1-aminium iodide, also known as choline iodide, is a quaternary ammonium salt commonly used in organic synthesis and biochemical research. It is a water-soluble compound derived from choline, an essential nutrient found in many foods. Choline iodide has been used as a source of choline groups in various chemical reactions and in microbiology as a selective agent for isolating bacteria. In addition, its potential role in cognitive impairment and liver disease has also been studied.
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Cat. No.: HY-W127656
CAS No.: 1927-06-6
Choline Bromide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-17552R
CAS No.: 28319-77-9
Synonyms: Choline Alfoscerate (Standard); Alpha-GPC (Standard); L-α-GPC (Standard)
sn-Glycero-3-phosphocholine (Standard) is the analytical standard of sn-Glycero-3-phosphocholine. This product is intended for research and analytical applications. sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia[1][2].
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Cat. No.: HY-145780
CAS No.: 3036-18-8
Purity:  99.29%
Cytidine 5′-diphosphoethanolamine is a cytidine diphosphate derivative. Cytidine 5′-diphosphoethanolamine serves as an intermediate in the biosynthesis of phosphatidylethanolamine . Cytidine 5′-diphosphoethanolamine stimulates choline uptake and acetylcholine (AChE) synthesis. Cytidine 5′-diphosphoethanolamine can be used in research related to phospholipid biosynthesis .
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Cat. No.: HY-N0076R
CAS No.: 33570-04-6
Synonyms: (-)-Bilobalide (Standard)
Bilobalide (Standard) is the analytical standard of Bilobalide. This product is intended for research and analytical applications. Bilobalide, a sesquiterpene trilactone constituent of Ginkgo biloba, inhibits the NMDA-induced efflux of choline with an IC50 value of 2.3 μM. Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells. Exerts protective and trophic effects on neurons .
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Cat. No.: HY-101036R
CAS No.: 87-67-2
Choline bitartrate (Standard) is the analytical standard of Choline bitartrate (HY-101036). This product is intended for research and analytical applications. Choline bitartrate is an orally active methylxanthine-derived choline salt of theophylline. Choline bitartrate exhibits weak antihistaminic and anticholinergic activities and can enhance the effects of histamine and acetylcholine. Choline bitartrate relaxes bronchial smooth muscle, dilates coronary and peripheral blood vessels, increases urine output and electrolyte excretion, stimulates central nervous system motor activity, and induces transient hypotension following a pressor phase. Choline bitartrate modulates sleep architecture by increasing wakefulness time and reducing slow-wave sleep, without altering the frequency or severity of nocturnal hypoxemia, apnea, or hypopnea events. Choline bitartrate is used in studies of bronchospasm, nocturnal asthma, and chronic asthma .
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Cat. No.: HY-W338346
CAS No.: 2016-36-6
Salicylate choline is an orally active derivative of Aspirin (acetylsalicylic acid) (HY-14654). Salicylate choline significantly reduces IL-1β, IL-6, TNF-α and IL-10 levels in cells. Salicylate choline enhances the anti-tumor activity of the CRM1 inhibitor Selinexor (KPT-330) (HY-17536) through inducing S-phase cell cycle arrest and impairing DNA damage repair. Salicylate choline combined with Selinexor demonstrates excellent anti-tumor efficacy in mice xenograft model harboring JeKo-1 cells. Salicylate choline can be used for the study of rheumatic diseases, inflammation and cancer .
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Cat. No.: HY-170805
CAS No.: 1327276-39-0
Target:  

Choline Kinase

Research Areas:  

Cancer

UNC0737 is an orthosteric choline kinase inhibitor. UNC0737 is also a poor inhibitor of G9a (IC50 = 5000 nM) and GLP (IC50 > 10000 nM) in the SAHH-coupled assays .
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Cat. No.: HY-124957
CAS No.: 31059-54-8
Purity:  ≥98.0%
Research Areas:  

Cancer

β-NETA is a potent and noncompetitive choline acetyltransferase (ChA; IC50=76 μM) and cholinesterase (ChE; IC50=40 μM) inhibitor. β-NETA weakly inhibits acetylcholinesterase (AChE; IC50=1 mM) .
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Cat. No.: HY-W127668
CAS No.: 5957-17-5
Triethylcholine iodide is a choline acetyltransferase inhibitor and a regulator of the acetylcholine synthesis pathway. Triethylcholine iodide inhibits acetylcholine synthesis in brain tissues and blocks neuromuscular and autonomic ganglionic transmission. Triethylcholine iodide exerts weak curare-like effects at extremely high concentrations. Triethylcholine iodide elevates the pentylenetetrazol seizure threshold, alters electroencephalogram patterns in Felis catus, but does not affect the maximal electroshock seizure threshold in Oryctolagus cuniculus. Triethylcholine iodide can be used in seizure-related research .
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Cat. No.: HY-B0739AR
CAS No.: 33818-15-4
Synonyms: Cytidine diphosphate-Choline sodium (Standard); CDP-Choline sodium (Standard); Cytidine 5'-diphosphoCholine sodium (Standard)
Citicoline sodium (Standard) is the analytical standard of Citicoline sodium. This product is intended for research and analytical applications. Citicoline sodium is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline sodium inhibits reactive oxygen species (ROS) and apoptosis. Citicoline sodium can be used for neurological disease and hearing loss study.
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Cat. No.: HY-100454
CAS No.: 104391-26-6
Purity:  99.65%
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

CGP 25454A is a selective presynaptic dopamine autoreceptor antagonist which induces the increase of dopamine and acetyl choline. CGP 25454A can be used for major depression research .
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Cat. No.: HY-150779S
CAS No.: 2483831-84-9
Choline-d13 (sulfate) is the deuterium labeled Choline sulfate .
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Cat. No.: HY-Y1242A
CAS No.: 123-41-1
Research Areas:  

Others

Choline hydroxide (46% in water) is a Choline hydrogen oxidized derivative and a strong organic base, can be used as the standard alkaline to adjust the pH of the medium. Choline is an orally active nutrient, serves as an important component of lecithin and sphingomyelin, promotes fat metabolism .
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Cat. No.: HY-124892A
CAS No.: 103994-00-9
Synonyms: Acetyl-AF64
Research Areas:  

Neurological Disease

Acetylethylcholine mustard hydrochloride (Acetyl-AF64) is an inhibitor of choline acetyl-transferase that reduces the contraction frequency of the myotubes by inhibiting the synthesis of acetylethylcholine (Ach) with the half-maximal inhibitory concentration (IC50) of 1.22 mM. Acetylethylcholine mustard hydrochloride is an irreversible ligand for the high affinity choline transport system. Acetylethylcholine mustard hydrochloride is also a cholinotoxin. Acetylethylcholine mustard hydrochloride is a precursor for ethylcholine mustard aziridinium ion .
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Cat. No.: HY-17552S
CAS No.: 2260669-07-4
Synonyms: Choline Alfoscerate-d9; Alpha-GPC-d9; L-α-GPC-d9
sn-Glycero-3-phosphocholine-d9 is the deuterium labeled sn-Glycero-3-phosphocholine. sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia .
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