2647 Results for "

Subunit

" in MedChemExpress (MCE) Product Catalog:
Products (2647)

2647 Results for "Subunit" in MCE Product Catalog:

  • Targets Recommended:
13
13 Cited Publications
Cat. No.: HY-P7278
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PDGFB; Platelet-Derived Growth Factor 2; Prev. SIS; PDGF Subunit B; Platelet-Derived Growth Factor Beta Polypeptide; PDGF2; Platelet-Derived Growth Factor Subunit B; Platelet-Derived Growth Factor, Beta Polypeptide (Oncogene SIS); Platelet-Derived Growth
Species:  
Rat
Source:  
E. coli
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12
12 Cited Publications
Cat. No.: HY-10082
CAS No.: 143621-35-6
Purity:  99.78%
Synonyms: 3-AP; PAN-811; OCX191
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Triapine (3-AP; PAN-811) is a potent inhibitor of the M2 subunit of ribonucleotide reductase (RR), and is a potent radiosensitizer.
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12
12 Cited Publications
Cat. No.: HY-16742B
CAS No.: 1624306-20-2
Research Areas:  

Infection

Gepotidacin mesylate hydrate is an orally active triazaacenaphthylene antibiotic and bacterial type II topoisomerase inhibitor. Gepotidacin mesylate hydrate inhibits bacterial DNA replication by blocking topoisomerase enzymes. Gepotidacin mesylate hydrate selectively inhibits topoisomerase IV and the B subunit of DNA gyrase .
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12
12 Cited Publications
Cat. No.: HY-N0877
CAS No.: 465-21-4
Bufalin is an active component isolated from Chan Su, acts as a potent Na +/K +-ATPase inhibitor, binds to the subunit α1, α2 and α3, with Kd of 42.5, 45 and 40 nM, respectively . Anti-cancer activity .
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10
10 Cited Publications
Cat. No.: HY-D0254
CAS No.: 2103-64-2
Synonyms: Pyrogallol phthalein
Target:  

PI3K

Research Areas:  

Cancer

Gallein is a Gβγ subunit signaling inhibitor that can interfere with the interaction between Gβγ subunit and PI3Kγ, regulate platelet function, and exhibit anti-tumor activity [1][3].
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10
10 Cited Publications
Cat. No.: HY-17029
CAS No.: 152044-54-7
Synonyms: EPO 906; Patupilone
Epothilone B is a microtubule stabilizer (MSA) with a Ki of 0.71μM, and is a MSA with blood-brain barrier permeability. Epothilone B acts by binding to the αβ-tubulin heterodimer subunit which causes decreasing of αβ-tubulin dissociation .
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10
10 Cited Publications
Cat. No.: HY-P7087
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PDGFB; Platelet-Derived Growth Factor 2; Prev. SIS; PDGF Subunit B; Platelet-Derived Growth Factor Beta Polypeptide; PDGF2; Platelet-Derived Growth Factor Subunit B; Platelet-Derived Growth Factor, Beta Polypeptide (Oncogene SIS); Platelet-Derived Growth
Species:  
Mouse
Source:  
E. coli
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10
10 Cited Publications
Cat. No.: HY-P80670
Synonyms: FTH1; FTH; FTHL6; OK/SW-cl.84; PIG15; Ferritin heavy chain; Ferritin H Subunit; Cell proliferation-inducing gene 15 protein

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat, Hamster

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9
9 Cited Publications
Cat. No.: HY-K1056

MCE G418 Selective Antibiotic, Sterile (50 mg/mL) is an aminoglycoside antibiotic produced by Micromonospora rhodorangea. It acts by binding to the 80S subunit of the bacterial ribosome, thus inhibiting protein synthesis in both prokaryotic and eukaryotic cells.

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9
9 Cited Publications
Cat. No.: HY-13993
CAS No.: 169274-78-6
Purity:  99.55%
Target:  

iGluR

Research Areas:  

Neurological Disease

Ro 25-6981 is a potent, selective and activity-dependent NR2B subunit specific NMDA receptor antagonist. Ro 25-6981 shows anticonvulsant and anti-parkinsonian activity. Ro 25-6981 has the potential for the research of parkinson's disease (PD) .
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9
9 Cited Publications
Cat. No.: HY-13993A
CAS No.: 1312991-76-6
Purity:  99.25%
Target:  

iGluR

Research Areas:  

Neurological Disease

Ro 25-6981 Maleate is a potent, selective and activity-dependent NR2B subunit specific NMDA receptor antagonist. Ro 25-6981 Maleat shows anticonvulsant and anti-parkinsonian activity. Ro 25-6981 Maleate has the potential for the research of parkinson's disease (PD) .
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9
9 Cited Publications
Cat. No.: HY-15317
CAS No.: 415713-60-9
Purity:  99.83%
Target:  

RAD51

Research Areas:  

Cancer

RI-1 is a RAD51 inhibitor, with IC50s ranging from 5 to 30 μM. RI-1 binds covalently to the surface of RAD51 protein at cysteine 319. RI-1 inactivates RAD51 by directly binding to a protein surface that serves as an interface between protein subunits in RAD51 filaments. RI-1 can disrupt homologous recombination in human cells .
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9
9 Cited Publications
Cat. No.: HY-N0215
CAS No.: 63-91-2
Synonyms: (S)-2-Amino-3-phenylpropionic acid
L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca + channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals .
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8
8 Cited Publications
Cat. No.: HY-12353A
CAS No.: 1629869-44-8
Purity:  99.40%
Synonyms: VX-787
Target:  

Influenza Virus

Research Areas:  

Infection

Pimodivir (VX-787) is an orally bioavailable inhibitor of influenza A virus polymerases through interaction with the viral PB2 subunit.
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8
8 Cited Publications
Cat. No.: HY-P80846
Synonyms: PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory Subunit alpha; PI3-kinase regulatory Subunit alpha; PI3K regulatory Subunit alpha; PtdIns-3-kinase regulatory Subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory Subunit alpha; PI3-kinase s

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF, ELISA

Reactivity:  

Human, Mouse, Rat

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8
8 Cited Publications
Cat. No.: HY-13234
CAS No.: 80621-81-4
Purity:  99.64%
Research Areas:  

Infection Cancer

Rifaximin, a gastrointestinal-selective antibiotic, binds the β-subunit of bacterial DNA-dependent RNA polymerase, resulting in inhibition of bacterial RNA synthesis. Rifaximin susceptibility is higher against Gram-positive strains (MIC: 0.03-5 mg/ml) compared to Gram-negative bacteria (MIC: 8-50 mg/mL) .
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8
8 Cited Publications
Cat. No.: HY-P81232
Synonyms: caspase-1 isoform alpha Subunit; CASP1; ICE; IL1BC; Caspase-1 Subunit p20; CASP 1; Caspase 1 apoptosis related cysteine peptidase; Caspase 1 apoptosis related cysteine protease; Caspase1; IL 1 beta converting enzyme; IL 1BC; IL1B convertase; IL1BCE; Interleukin 1 beta convertase; Interleukin 1 beta convertase precursor; Interleukin 1 beta converting enzyme; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45; CASP1_HUMAN; CASP1_MOUSE.

Host:  

Rabbit

Application:  

WB, IHC-P, IHC-F, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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7
7 Cited Publications
Cat. No.: HY-P1411
CAS No.: 880107-52-8
Synonyms: PcTx1; Psalmopoeus cambridgei toxin-1
Research Areas:  

Neurological Disease Cancer

Psalmotoxin 1 (PcTx1) is a protein toxin that can bind at subunit-subunit interfaces of acid-sensing ion channel 1a (ASIC1a). Psalmotoxin 1 is a potent and slective ASIC1a inhibitor (IC50: 0.9 nM) by increasing the apparent affinity for H + of ASIC1a. Psalmotoxin 1 can induce cell apoptosis, also inhibits cell migration, proferliration and invasion of cancer cells. Psalmotoxin 1 can be used in the research of cancers, or neurological disease .
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7
7 Cited Publications
Cat. No.: HY-P1411A
Synonyms: PcTx1 TFA; Psalmopoeus cambridgei toxin-1 TFA
Research Areas:  

Neurological Disease Cancer

Psalmotoxin 1 (PcTx1) TFA is a protein toxin that can bind at subunit-subunit interfaces of acid-sensing ion channel 1a (ASIC1a). Psalmotoxin 1 TFA is a potent and slective ASIC1a inhibitor (IC50: 0.9 nM) by increasing the apparent affinity for H + of ASIC1a. Psalmotoxin 1 TFA can induce cell apoptosis, also inhibits cell migration, proferliration and invasion of cancer cells. Psalmotoxin 1 TFA can be used in the research of cancers, or neurological disease .
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7
7 Cited Publications
Cat. No.: HY-148800
CAS No.: 2649467-58-1
Purity:  99.96%
Synonyms: VX-548
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

Suzetrigine (VX-548) is an orally active and highly selective NaV1.8 inhibitor that acts as an analgesic. Suzetrigine is also a blocker of sodium channel protein type 10 subunit alpha. Suzetrigine is promising for research of acute pain after abdominoplasty and bunionectomy .
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