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Gallein

(Synonyms: Pyrogallol phthalein)
10 Cited Publications
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Based on 10 publication(s) in Google Scholar

Gallein is a Gβγ subunit signaling inhibitor that can interfere with the interaction between Gβγ subunit and PI3Kγ, regulate platelet function, and exhibit anti-tumor activity[1][3].

For research use only. We do not sell to patients.

  • Purity: 98.0%
  • CAS No.: 2103-64-2
  • Formula: C20H12O7
  • Molecular Weight:364.31
  • Storage:

    4°C, protect from light

    * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

  • Gallein Chemical Structure
    Gallein Chemical Structure
  • Experimental Validation Results for Gallein
  • Experimental Validation Results for Gallein
  • Experimental Validation Results for Gallein
  • Experimental Validation Results for Gallein
  • Experimental Validation Results for Gallein
CAS No.: 2103-64-2
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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WBIn Vivo Efficacy Study
  • In Vivo Efficacy Study
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  • WB
  • In Vivo Efficacy Study
  • In Vivo Efficacy Study

All PI3K Isoforms

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  • Gallein Chemical Structure
    Gallein Chemical Structure
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  • 1/16

    Gallein purchased from MedChemExpress. Usage Cited in: Water Biol Secur. 2025 Sep 18.

    Customer Validation
     The percentage of mandarin fish ingesting live fish fry after 2-h immersion in the Gβγ signaling inhibitor Gallein (0.01, 0.1, and 1 μmol/L) across treatment groups.

  • 1/16

    Gallein purchased from MedChemExpress. Usage Cited in: Nat Metab. 2024 Apr;6(4):708-723. [Abstract]

    Customer Validation
     Statistic result showing that in the SVF-derived adipocytes, treatment with inhibitor for Gαi (PTX) or Gβγ (Gallein, 10 μM, pretreated with 4 h) abolished the lactate-induced activation of ATF2.

  • 1/16

    Gallein purchased from MedChemExpress. Usage Cited in: Nat Metab. 2024 Apr;6(4):708-723. [Abstract]

    Customer Validation
     Representative western blots and statistical results showing that the lactate-induced activation of p38-ATF2 and upregulation of UCP1 were blocked by inhibitor for Gαi (PTX) or Gβγ (Gallein, 10 μM, pretreated with 4 h).

  • 1/16

    Gallein purchased from MedChemExpress. Usage Cited in: Nat Metab. 2024 Apr;6(4):708-723. [Abstract]

    Customer Validation
     Injection of inhibitor for p38 (SB203580), ROCK1 (Y-27632) or Gβγ (Gallein, 10 μM, pretreated with 4 h) into the inguinal fat pads in the tumour-bearing mice alleviated tumour-induced losses of body weight .

  • 1/16

    Gallein purchased from MedChemExpress. Usage Cited in: Nat Metab. 2024 Apr;6(4):708-723. [Abstract]

    Customer Validation
     Injection of inhibitor for p38 (SB203580), ROCK1 (Y-27632) or Gβγ (Gallein, 10 μM, pretreated with 4 h) into the inguinal fat pads in the tumour-bearing mice alleviated tumour-induced losses of tissue weights.

  • Gallein