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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
244 Results for "
ocular
" in MedChemExpress (MCE) Product Catalog:
Products (244)
244 Results for "ocular" in MCE Product Catalog:
Cat. No.: HY-P990689
CAS No.: 2517939-46-5
Synonyms: RO-7250284
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Synonyms: QLS-101
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Foslevcromakalim (QLS-101) is a ATP-sensitive potassium channel opener. Foslevcromakalim is the proagent used for ocular hypotensive effect .
Synonyms: Hydrocortisone 21-phosphate sodium; Cortisol 21-phosphate sodium
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Hydrocortisone phosphate sodium is a soft steroid with low anti-inflammatory properties and a short duration of action. Hydrocortisone phosphate sodium can be used for the research for several ocular conditions and gastric ulcers .
Cat. No.: HY-P5840
CAS No.: 1206475-79-7
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Synonyms: SYL1001
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Tivanisiran (SYL1001) is a small interfering RNA (siRNA) targeting TRPV1 . Tivanisiran induces the degradation of TRPV1 mRNA, thereby inhibiting protein synthesis. Tivanisiran alleviates ocular discomfort and pain, and improves ocular hyperemia and tear quality. Tivanisiran is applicable to research related to dry eye disease .
Cat. No.: HY-128538
CAS No.: 1262873-06-2
Synonyms: ONO-9054
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Sepetaprost (ONO-9054) is a dual agonist of the prostaglandin E3 receptor and prostaglandin F receptor. Sepetaprost reduces intraocular pressure in animal models. Sepetaprost is applicable for research on ocular hypertension and open-angle glaucoma .
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Cryosim-3 is a selective TRPM8 receptor agonist. Cryosim-3 increases tear secretion and relieves ocular discomfort in animal models .
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Anecortave acetate is a potent ocular angiostatic agent. Anecortave acetate inhibits neovascularization which is induced by many different angiogenic factors, and increases plasminogen activator inhibitor-1 (PAI-1) mRNA expression. Anecortave acetate can be used to research ocular neovascular diseases .
Cat. No.: HY-136081A
CAS No.: 659-40-5
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Hexamidine diisethionate is an antimicrobial agent targeting Acanthamoeba protozoa. Hexamidine diisethionate is promising for research of ocular infectious diseases such as Acanthamoeba keratitis .
Cat. No.: HY-B1888
CAS No.: 91714-94-2
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Bromfenac is a potent and orally active inhibitor of COX, with IC50s of 5.56 and 7.45 nM for COX-1 and COX-2, respectively. Bromfenac can be used in ocular inflammation research .
Cat. No.: HY-B1754
CAS No.: 49697-38-3
Synonyms: Org 6216; Rimexel
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Rimexolone (Org 6216) is a glucocorticoid steroid with anti-inflammatory activity. Rimexolone can be used as a 1% ophthalmic suspension for the management of ocular inflammation .
Cat. No.: HY-178231
CAS No.: 2766583-86-0
Synonyms: ALK5-IN-85
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Finbosertib (ALK5-IN-85) (Compound 19) is a TGFβRI (ALK5) inhibitor with an IC50 of <100 nM. Finbosertib can be used for respiratory diseases including idiopathic pulmonary fibrosis, asthma, COPD and lumg cancer, and dermal and ocular fibrotic conditions research .
Cat. No.: HY-158821A
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ISTH0036 sodium is a phosphorothioate LNA-modified antisense oligonucleotide gapmer that selectively targets and downregulates TGF-β2 mRNA. ISTH0036 sodium suppresses TGF-β2 expression, reduces choroidal neovascularization and vascular leakage, inhibits fibrosis, blocks epithelial-to-mesenchymal transition, and inhibits angiogenesis while promoting bleb survival. ISTH0036 sodium exhibits long-lasting, dose-dependent ocular tissue distribution and target engagement in rabbit and non-human primate eyes. ISTH0036 sodium can be used for the study of various ocular disorders, such as glaucoma and neovascular retinal diseases .
Cat. No.: HY-17425B
CAS No.: 1218948-84-5
Synonyms: Valaciclovir hydrochloride hydrate
Valacyclovir hydrochloride hydrate is a potent antiviral agent. Valacyclovir hydrochloride hydrate can be used in the management of herpes simplex, herpes zoster and herpes B. Valacyclovir hydrochloride hydrate can be formulate ocular inserts for the research of ocular herpes. Valacyclovir hydrochloride hydrate is a precursor and can be rapidly converted into acyclovir in vivo .
Cat. No.: HY-151611
CAS No.: 2842774-51-8
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UAMC-00050 is a potent trypsin-like serine protease inhibitor. UAMC-00050 can be used in research of dry eye syndrome and ocular inflammation .
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AL-34662 is a selective 5-HT2A receptoragonist (IC50: 0.77 nM and 1.5 nM for rat and human 5-HT2 receptor). AL-34662 is also a weak α-1D adrenergic agonist activity (EC50:0.4 μM). AL-34662 is an ocular hypotensive agent .
Cat. No.: HY-B1888AR
CAS No.: 91714-93-1
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Bromfenac (sodium) (Standard) is the analytical standard of Bromfenac (sodium). This product is intended for research and analytical applications. Bromfenac sodium is a potent and orally active inhibitor of COX, with IC50s of 5.56 and 7.45 nM for COX-1 and COX-2, respectively. Bromfenac sodium can be used in ocular inflammation research .
Cat. No.: HY-110161
CAS No.: 1021912-42-4
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sst2 Receptor agonist-1 is a potent somatostatin receptor subtype 2 (sst2) agonist with a Ki value of 0.025 nM and a cAMP IC50 value of 4.8 nM. sst2 Receptor agonist-1 can inhibit rat growth hormone (GH) secretion and ocular neovascular lesion formation. Antiangiogenic effect .
Cat. No.: HY-B0584R
CAS No.: 157283-68-6
Synonyms: Fluprostenol isopropyl ester(Standard); AL6221(Standard); Flu-Ipr (Standard)
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Travoprost (Standard) is the analytical standard of Travoprost. This product is intended for research and analytical applications. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension .
Cat. No.: HY-101804
CAS No.: 125720-84-5
Synonyms: CDDD-1815
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(E)-Alprenoxime is the isomer of the Alprenoxime. Alprenoxime is a site-activated ocular β-blocker.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
