Valacyclovir hydrochloride hydrate
Based on 1 publication(s) in Google Scholar
Valacyclovir hydrochloride hydrate is a potent antiviral agent. Valacyclovir hydrochloride hydrate can be used in the management of herpes simplex, herpes zoster and herpes B. Valacyclovir hydrochloride hydrate can be formulate ocular inserts for the research of ocular herpes. Valacyclovir hydrochloride hydrate is a precursor and can be rapidly converted into acyclovir in vivo.
For research use only. We do not sell to patients.
- CAS No.: 1218948-84-5
- Formula: C13H20N6O4.ClH.xH2O
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Valacyclovir hydrochloride hydrate
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Biological Activity
Description
Chemical Information
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CAS No. 1218948-84-5
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Formula C13H20N6O4.ClH.xH2O
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SMILES
N[C@@H](C(C)C)C(OCCOCN1C=NC2=C1N=C(N)NC2=O)=O.[H]Cl.O.[x]
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Synonyms
Valaciclovir hydrochloride hydrate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Front Pharmacol
2020 Mar 11:11:248. PMID: 32218733
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
References
[1]. Zhang Y,et al. Acute renal injury induced by valacyclovir hydrochloride: A case report. Exp Ther Med. 2016 Dec;12(6):4025-4028. [Content Brief]
[2]. Shadambikar G, et al. Novel Application of Hot Melt Extrusion Technology for Preparation and Evaluation of Valacyclovir Hydrochloride Ocular Inserts. AAPS PharmSciTech. 2021 Jan 14;22(1):48. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Valacyclovir hydrochloride hydrate Related Classifications
HY-17425B Related Classifications
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