76 Results for "

Non-structural protein

" in MedChemExpress (MCE) Product Catalog:
Products (76)

76 Results for "Non-structural protein" in MCE Product Catalog:

Cat. No.: HY-10300R
CAS No.: 865466-24-6
Synonyms: SCH 900518 (Standard); Arlansa (Standard)
Research Areas:  

Infection

Narlaprevir (Standard) is the analytical standard of Narlaprevir. This product is intended for research and analytical applications. Narlaprevir (SCH 900518) is a selective and orally bioavailable NS3 protease inhibitor with a Ki value of 6 nM and an EC90 value of 40 nM . Narlaprevir also inhibits the HCV nonstructural protein 3 serine protease . Narlaprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 2.3 μM .
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Cat. No.: HY-W003943
CAS No.: 903899-13-8
Research Areas:  

Infection

6-Hydroxypyridin-3-ylboronic acid is a heterocyclic building block, which can be used in the synthesis of non-nucleoside inhibitors of hepatitis C virus (HCV) RNA-dependent RNA polymerase nonstructural protein 5B (NS5B). 6-Hydroxypyridin-3-ylboronic acid has also been used in the synthesis of mammalian target of rapamycin (mTOR) inhibitors .
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Cat. No.: HY-171587
CAS No.: 69383-05-7
Target:  

HCV

Research Areas:  

Infection

3′-Deoxy CTP is a nucleotide analogue and a mandatory chain terminator. 3′-Deoxy CTP can cause chain termination by lacking the 3′-hydroxyl group, inhibiting the RNA synthesis activity of HCV nonstructural protein (NS5B) polymerase and blocking viral replication. 3′-Deoxy CTP can be used to study the chain termination mechanism of HCV polymerase and the development of antiviral drugs .
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Cat. No.: HY-W749691
Synonyms: (S)-GS-5816-13C,d3
(S)-Velpatasvir- 13C,d3 ((S)-GS-5816- 13C,d3) is 13C labeled Velpatasvir. Velpatasvir (VEL, GS-5816) is a novel pan-genotypic hepatitis C virus (HCV) nonstructural protein 5A (NS5A) inhibitor with activity against genotype 1 (GT1) to GT6 HCV replicons. Velpatasvir is also a SARS-CoV 3CL pro inhibitor with an IC50 of 2.16 μM .
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Cat. No.: HY-P76592
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Non-structural protein 9; NSP9; ORF1a polyprotein; ORF1ab polyprotein; p12
Species:  
Virus
Source:  
E. coli
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Cat. No.: HY-12530S3
Synonyms: GS-5816-13C,d3
Velpatasvir- 13C,d3 (GS-5816- 13C,d3) is 13C and deuterium labeled Velpatasvir. Velpatasvir (VEL, GS-5816) is a novel pan-genotypic hepatitis C virus (HCV) nonstructural protein 5A (NS5A) inhibitor with activity against genotype 1 (GT1) to GT6 HCV replicons. Velpatasvir is also a SARS-CoV 3CL pro inhibitor with an IC50 of 2.16 μM .
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Cat. No.: HY-171587A
Target:  

HCV

Research Areas:  

Infection

3′-Deoxy CTP trisodium is the sodium salt form of 3′-Deoxy CTP (HY-171587). 3′-Deoxy CTP trisodium is a nucleotide analogue and a mandatory chain terminator. 3′-Deoxy CTP trisodium can cause chain termination by lacking the 3′-hydroxyl group, inhibiting the RNA synthesis activity of HCV nonstructural protein (NS5B) polymerase and blocking viral replication. 3′-Deoxy CTP trisodium can be used to study the chain termination mechanism of HCV polymerase and the development of antiviral drugs .
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Cat. No.: HY-175234
CAS No.: 3107145-13-8
Research Areas:  

Infection

CHIKV nsP2 protease-IN-2 (Compound 2o) is a allosteric nonstructural protein 2 helicase (nsP2hel) inhibitor with IC50s of 0.5  μM and 0.9  μM for nsP2 ATPase and RNA unwindase, respectively. CHIKV nsP2 protease-IN-2 has broad-spectrum antialphaviral activity against chikungunya virus (CHIKV), Mayaro virus (MAYV), and Venezuelan equine encephalitis virus (VEEV) (EC50 of 120 nM for CHIKV-nLuc). CHIKV nsP2 protease-IN-2 can be used for alphaviruses infections research .
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Cat. No.: HY-P5510
CAS No.: 188530-20-3
Synonyms: HCV NS3 protease substrate
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu-ψ-(COO)Ala-Ser-Lys(DABCYL)-NH2 (HCV NS3 protease substrate) is a biological active peptide. (This peptide is a HCV protease substrate incorporating an ester bond between residues P1 and P1. Due to ready transesterification of the scissile bond to the acyl-enzyme intermediate, this substrate shows very high kcat/Km values, enabling detection of activity with subnanomolar nonstructural protein 3 (NS3 protease) concentrations. It is widely used for the continuous assay of NS3 protease activity. Substrate cleavage is proportional to the enzyme concentration with a detection limit for NS3 between 1 nM and 250 pM.
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Cat. No.: HY-P77831
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Replicase polyprotein 1a; pp1a; ORF1a polyprotein; Host translation inhibitor nsp1; Leader protein, Non-structural protein 1 (nsp1); Non-structural protein 2 (nsp2); p65 homolog; Papain-like protease nsp3; EC:3.2.2.-; EC:3.4.19.12; EC:3.4.22.-; Non-struct
Species:  
Virus
Source:  
E. coli
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Cat. No.: HY-P702190
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Replicase polyprotein 1a; pp1a; ORF1a polyprotein; Host translation inhibitor nsp1; Leader protein, Non-structural protein 1 (nsp1); Non-structural protein 2 (nsp2); p65 homolog; Papain-like protease nsp3; EC:3.2.2.-; EC:3.4.19.12; EC:3.4.22.-; Non-struct
Species:  
Virus
Source:  
E. coli
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Cat. No.: HY-P703532
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Replicase polyprotein 1ab; pp1ab; ORF1ab polyprotein; Host translation inhibitor nsp1; Leader protein; Non-structural protein 1 (nsp1); Non-structural protein 2 (nsp2); p65 homolog; Papain-like protease nsp3 (EC:3.2.2.-, EC:3.4.19.12, EC:3.4.22.-); Non-
Species:  
Virus
Source:  
E. coli
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Cat. No.: HY-P703533
Synonyms: Replicase polyprotein 1ab; pp1ab; ORF1ab polyprotein; Host translation inhibitor nsp1; Leader protein; Non-structural protein 1 (nsp1); Non-structural protein 2 (nsp2); p65 homolog; Papain-like protease nsp3 (EC:3.2.2.-, EC:3.4.19.12, EC:3.4.22.-); Non-
Species:  
Virus
Source:  
E. coli
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Cat. No.: HY-P811944
Synonyms: TBC1D23; TBC1 Domain Family Member 23; HCV Non-structural protein 4A-Transactivated protein 1; FLJ11046; NS4ATP1; HCV Nonstructural protein 4A-Transactivated protein 1; TBC1 Domain Family, Member 23; PCH11

Host:  

Mouse

Application:  

WB, FC

Reactivity:  

Human

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Cat. No.: HY-P811944A
Synonyms: TBC1D23; TBC1 Domain Family Member 23; HCV Non-structural protein 4A-Transactivated protein 1; FLJ11046; NS4ATP1; HCV Nonstructural protein 4A-Transactivated protein 1; TBC1 Domain Family, Member 23; PCH11

Host:  

Mouse

Application:  

WB, FC

Reactivity:  

Human

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Cat. No.: HY-169998
Target:  

SARS-CoV

Research Areas:  

Infection

XJ5 is a non-nucleoside covalent inhibitor of Nsp12 (IC50=0.12 μM), which is the non-structural protein 12 of the virus. XJ5 has the potential to be an antiviral inhibitor of SARS-CoV-2 .
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Cat. No.: HY-P703397
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NSMCE1; NSE1; NSE1 Component Of SMC5/6 Complex; Non-SMC Element 1 Homolog; NSE1 Homolog, SMC5-SMC6 Complex Component; Non-SMC Element 1 Homolog (S. Cerevisiae); Non-structural Maintenance Of Chromosomes Element 1 Homolog
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P703398
Synonyms: NSMCE1; NSE1; NSE1 Component Of SMC5/6 Complex; Non-SMC Element 1 Homolog; NSE1 Homolog, SMC5-SMC6 Complex Component; Non-SMC Element 1 Homolog (S. Cerevisiae); Non-structural Maintenance Of Chromosomes Element 1 Homolog
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P74684
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PTPN11; protein Tyrosine Phosphatase Non-Receptor Type 11 Isoform 1; Prev. NS1; Tyrosine-protein Phosphatase Non-Receptor Type; SH-PTP2; protein-Tyrosine-Phosphatase; PTP2C; Noonan Syndrome 1; BPTP3; CDNA, FLJ92431; SHP-2; PTPN11 protein; SHP2; METCDS; SH
Species:  
Virus
Source:  
E. coli
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Cat. No.: HY-P991774

Target:  

Flavivirus

Research Areas:  

Infection

Anti-West Nile virus NS1 Antibody (10NS1) reacts with non-structural protein 1 (NS1) of West Nile virus (WNV). Anti-West Nile virus NS1 Antibody (10NS1) offers significant protection against flaviviral infections in vivo. Recommend Isotype Controls: Mouse IgG2a kappa, Isotype Control (HY-P99978) .
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