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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
143 Results for "
Platelet-activating factor
" in MedChemExpress (MCE) Product Catalog:
Products (143)
143 Results for "Platelet-activating factor" in MCE Product Catalog:
Cat. No.: HY-118019
CAS No.: 23758-16-9
Cat. No.: HY-101731
CAS No.: 167011-22-5
Target:
Research Areas:
CP-96021 hydrochloride is a balanced, combined, potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonist with Ki values of 34 nM and 37 nM, respectively .
Cat. No.: HY-101675
CAS No.: 132418-35-0
Synonyms: BN-50727
Research Areas:
Setipafant is a platelet-activating factor (PAF) antagonist.
Cat. No.: HY-10164
CAS No.: 131614-02-3
Research Areas:
E-6123 is a platelet-activating factor (PAF) receptor antagonist.
Cat. No.: HY-N3054
CAS No.: 40433-82-7
Category:
Cat. No.: HY-P2606
CAS No.: 118850-72-9
Research Areas:
Cat. No.: HY-100153
CAS No.: 93363-11-2
Synonyms: (Rac)-RP-55778
Research Areas:
48740 RP ((Rac)-RP-55778) is a platelet-activating factor (PAF) antagonist.
Cat. No.: HY-136791
CAS No.: 120908-94-3
Research Areas:
BN 52115, a platelet-activating factor antagonist, has demonstrated the ability to mitigate bronchopulmonary changes in vivo.
Cat. No.: HY-108635R
CAS No.: 74389-68-7
Synonyms: PAF (C16) (Standard)
Cat. No.: HY-167719
CAS No.: 188913-58-8
Synonyms: UR-12746 free base
Research Areas:
Dersalazine (UR-12746 free base) is an inhibitor of platelet-activating factor, exhibiting intestinal anti-inflammatory activity and potential efficacy in treating ulcerative colitis.
Cat. No.: HY-171253
CAS No.: 54123-06-7
Research Areas:
Clotizolam is a thienobenzodiazepine derivative that has antagonistic activity against platelet-activating factor (PAF). Clotizolam possesses sedative, anxiolytic, anticonvulsant,and muscle relaxant effects .
Cat. No.: HY-123505
CAS No.: 367249-56-7
Synonyms: UR-12746 sodium
Research Areas:
Dersalazine (sodium) is a platelet-activating factor (PAF) antagonist. Dersalazine (sodium) can exert intestinal anti-inflammatory activity in rodent colitis models by downregulating IL-17 expression .
Cat. No.: HY-N1208
CAS No.: 21040-64-2
Synonyms: O-Acetylspiradine G; Spiradine G acetate
Category:
Alkaloids Pyrrole Alkaloids Rosaceae Spiraea japonica Plants
Target:
Cat. No.: HY-N9300
CAS No.: 57430-03-2
Category:
Cat. No.: HY-133003
CAS No.: 122328-38-5
Research Areas:
L662,025 is a specific, photolabile and irreversible Platelet-activating factor (PAF-receptor) antagonist, with IC50 values of 5.6 μM (platelet aggregation) and 1 μM (receptor binding), respectively .
Cat. No.: HY-P71185
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PAFAH1B2; Platelet-activating factor Acetylhydrolase, Isoform Ib, Beta Subunit 30kDa; Platelet activating factor Acetylhydrolase 1b Catalytic Subunit 2; Platelet-activating factor Acetylhydrolase, Isoform Ib, Subunit 2 (30kDa); Platelet-activating factor
Species:
Human
Source:
E. coli
Cat. No.: HY-N2247A
CAS No.: 88547-66-4
Cat. No.: HY-125309
CAS No.: 161395-35-3
Research Areas:
ABT-299 is a prodrug of a platelet-activating factor (PAF) antagonist that exhibits significant inhibitory activity on PAF-induced β-platelet globulin release in vitro after in vivo administration in humans, an effect that may be partially attributed to the pyridine-N-oxide metabolite.
Cat. No.: HY-19205A
CAS No.: 193739-23-0
Synonyms: LDP-392
Research Areas:
CMI-392 (LDP-392) is an orally active dual 5-lipoxygenase inhibitor and platelet-activating factor receptor (PAFR) antagonist, with an IC50 of 10 nM for human PAF receptor and an IC50 of 100 nM for rat 5-lipoxygenase. CMI-392 blocks PAF receptor binding, inhibits leukotriene synthesis, attenuates PAF-induced hemoconcentration, and suppresses arachidonic acid- and TPA-induced ear swelling in mice. CMI-392 reduces inflammatory cell infiltration, decreases MPO levels, alleviates ocular inflammation, and improves dextran sulfate sodium-induced colitis. CMI-392 can be used in the research of inflammatory and immune-related diseases such as colitis and atopic dermatitis .
Cat. No.: HY-132210
CAS No.: 116673-45-1
Research Areas:
rel-(2R,4R)-2,4-Bis(3,4,5-trimethoxyphenyl)-1,3-dioxolane (compound 6) is a platelet-activating factor receptor (PAFR) antagonist with a Ki of 0.3 µM .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
