Pinusolidic acid
Pinusolidic acid is a platelet-activating factor (PAF) inhibitor with an IC50 of 23 μM.
For research use only. We do not sell to patients.
- CAS No.: 40433-82-7
- Formula: C20H28O4
- Molecular Weight:332.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>40 μM
Compound: 21
|
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
|
[PMID: 23691952] |
| HL-60 | IC50 |
>40 μM
Compound: 21
|
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
|
[PMID: 23691952] |
| MCF7 | IC50 |
>40 μM
Compound: 21
|
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 23691952] |
| SMMC-7721 | IC50 |
>40 μM
Compound: 21
|
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay
Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay
|
[PMID: 23691952] |
| SW480 | IC50 |
>40 μM
Compound: 21
|
Cytotoxicity against human SW480 cells after 48 hrs by MTT assay
Cytotoxicity against human SW480 cells after 48 hrs by MTT assay
|
[PMID: 23691952] |
| Vero | CC50 |
>750 μM
Compound: 9
|
Cytotoxicity against Vero E6 cells by MTT assay
Cytotoxicity against Vero E6 cells by MTT assay
|
[PMID: 17663539] |
| Vero | EC50 |
4.71 μM
Compound: 9
|
Antiviral activity against SARS coronavirus in Vero E6 cells assessed as inhibition of viral replication by ELISA
Antiviral activity against SARS coronavirus in Vero E6 cells assessed as inhibition of viral replication by ELISA
|
[PMID: 17663539] |
Chemical Information
-
CAS No. 40433-82-7
-
Molecular Weight 332.43
-
Formula C20H28O4
-
SMILES
C[C@@]12[C@](CCC([C@@H]2CCC3=CCOC3=O)=C)([H])[C@](C)(CCC1)C(O)=O
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Structure Classification
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Initial Source
Antrodia camphorata
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)