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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
109 Results for "
acidification
" in MedChemExpress (MCE) Product Catalog:
Products (109)
109 Results for "acidification" in MCE Product Catalog:
Cat. No.: HY-185057
CAS No.: 41656-56-8
Synonyms: S-Lactylglutathione; (R)-S-Lactoylglutathione
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Cat. No.: HY-P0014AS
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Cat. No.: HY-164532
CAS No.: 265646-94-4
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NS3736 is an orally effective chloride channel inhibitor that can be used for the research of osteoporosis. NS3736 targets the CIC-7 channel in osteocytes, blocks osteoclast acidification and resorption in vitro, with IC50=30 μM. In a rat model of ovariectomy-induced osteoporosis, NS3736 can enhance bone strength and bone density .
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Sipasterol (5α-Androstane-3β,5,6β-triol) is a neuroprotectant. Sipasterol can remarkably reverse intracellular acidification and alleviate neuronal injury through the inhibition of AMPK signaling. Sipasterol remarkably reduced the infarct volume and attenuated neurologic impairment in acute ischemic stroke models of middle cerebral artery occlusion in vivo .
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(E/Z)-3PO is a potent PFKFB3 inhibitor. (E/Z)-3PO can inhibit the glycolysis process, reduce the extracellular acidification rate, and inhibit the capillary tube formation, migration of endothelial cells, and the formation of aortic sprouts, thereby suppressing angiogenesis. (E/Z)-3PO is promising for research of diseases such as cancer, acute lung injury, pulmonary fibrosis, and atherosclerosis .
Cat. No.: HY-169089A
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Cat. No.: HY-P0014A
CAS No.: 1997361-86-0
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Cat. No.: HY-P10318
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Cat. No.: HY-P1614
CAS No.: 1026276-22-1
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Cat. No.: HY-P0041A
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Cat. No.: HY-P10975
CAS No.: 2484874-12-4
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Cat. No.: HY-P0014S2
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Cat. No.: HY-113560
CAS No.: 103955-73-3
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Cat. No.: HY-P3143A
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BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50 of 7.68 nM. BMSpep-57 hydrochloride binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hydrochloride facilitates T cell function by in creasing IL-2 production in PBMCs .
Cat. No.: HY-P1162
CAS No.: 73168-24-8
Synonyms: SKF 100273
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Cat. No.: HY-P10910
CAS No.: 2919344-88-8
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Cat. No.: HY-P11243
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Cat. No.: HY-N14423
CAS No.: 144450-34-0
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Cat. No.: HY-N14425
CAS No.: 144450-35-1
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Cat. No.: HY-122077
CAS No.: 674299-39-9
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NS5818 is a potent chloride channel inhibitor. NS5818 inhibits acidification and bone resorption. NS5818 has the potential for the research of osteoporosis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
