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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
73 Results for "
pH sensitive
" in MedChemExpress (MCE) Product Catalog:
Products (73)
73 Results for "pH sensitive" in MCE Product Catalog:
Cat. No.: HY-W040291
CAS No.: 96735-88-5
Cat. No.: HY-168913
CTT2274 is a prodrug of MMAE (HY-15162). CTT2274 is composed of a prostate-specific membrane antigen (PSMA)-binding scaffold, a biphenyl motif, a pH-sensitive phosphoramidate linker, and MMAE payload. CTT2274 shows selective binding to PSMA and delivers MMAE. CTT2274 inhibits prostate cancer .
Cat. No.: HY-D2745
CAS No.: 1638544-48-5
Cat. No.: HY-W024881
CAS No.: 184351-56-2
Synonyms: 2,3,3-Trimethylindolenine-5-sulfonic acid potassium salt
Target:
Research Areas:
Potassium 2,3,3-trimethylindole-5-sulfonate (2,3,3-Trimethylindolenine-5-sulfonic acid potassium salt) is a sulfonated indoline compound, and also serves as the starting indole raw material for the synthesis of pH-sensitive near-infrared cyanine dye HCyC-646 and near-infrared fluorescent probe IR-793. Potassium 2,3,3-trimethylindole-5-sulfonate can be used in lung adenocarcinoma-related research .
Cat. No.: HY-D1224A
CAS No.: 99792-50-4
Synonyms: CPRG sodium
Cat. No.: HY-126470A
CAS No.: 474942-73-9
Synonyms: pHCPamHcy
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Research Areas:
N-Palmitoyl homocysteine (PHC) ammonium is a pH sensitive lipid hat is cleaved under endosomal pH conditions (pH 5.5) .
Cat. No.: HY-145616
CAS No.: 1234218-62-2
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Research Areas:
Sudocetaxel is a microtubule depolymerization inhibitor for pH-sensitive docetaxel delivery.
Cat. No.: HY-W353607A
CAS No.: 102185-52-4
Cat. No.: HY-W145108
CAS No.: 63451-28-5
Cat. No.: HY-172385
CAS No.: 108032-13-9
Synonyms: 1,2-Dipalmitoyl-sn-glycero-3-succinate
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Research Areas:
16:0 DGS (1,2-Dipalmitoyl-sn-glycero-3-succinate) can be used for the preparation of pH-sensitive liposomes .
Cat. No.: HY-129563
CAS No.: 150608-41-6
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CGP 57813 is a peptidomimetic inhibitor of HIV protease that can be encapsulated by nanoparticles composed of poly(D,L-lactic acid) (PLA) and pH-sensitive methacrylic acid copolymers and delivered into the body .
Cat. No.: HY-D0023A
Synonyms: HPTS hydrate; Solvent Green 7 hydrate
Cat. No.: HY-D0116
CAS No.: 27928-00-3
Synonyms: HPTS free acid; Solvent Green 7 free acid
Cat. No.: HY-155717
CAS No.: 2958641-42-2
NDBM is a probe and binds to tumor-specific Pim-1 kinase, releases strong fluorescence, and produces cytotoxicity, thus achieving cell screening and killing effects. NDBM can specifically target lysosomes and sensitively respond to pH. NDBM can be used to track the pH changes in the intracellular environment under conditions of autophagy and external stimulation .
Cat. No.: HY-D1593
CAS No.: 2923990-43-4
Cat. No.: HY-D1772
CAS No.: 53340-16-2
Cat. No.: HY-D2768
CAS No.: 467233-93-8
Cat. No.: HY-113621B
CAS No.: 2757574-06-2
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Research Areas:
Ageladine A dihydrochloride is an inhibitor of matrix metalloproteinase (MMP) isolated from the marine sponge Agelas nakamurai, possessing anti-angiogenic activity. Ageladine A dihydrochloride not only inhibits MMP-2 but also MMP-1, MMP-8, MMP-9, MMP-12, and MMP-13, with IC50 values of 4.65 μM, 2.79 μM, 907.12 nM, 1.83 μM, 767.57 nM, and 1.09 μM, respectively. Additionally, Ageladine A dihydrochloride is a pH-sensitive membrane-permeable dye that emits fluorescence in the blue-green range upon UV excitation, featuring a maximum absorption peak at 370 nm. Furthermore, Ageladine A dihydrochloride serves as a reliable and stable fluorescent pH sensor for detecting changes in intracellular pH values .
Cat. No.: HY-174358A
CAS No.: 39927-08-7
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Research Areas:
HOOC-PEG2000-COOH is a dicarboxyl-terminated polyethylene glycol and calcium ion chelator. HOOC-PEG2000-COOH inhibits platelet aggregation and contraction while promoting fibrinolysis and blood clot dissolution. HOOC-PEG2000-COOH can serve as a coating for superparamagnetic iron oxide nanoparticles in nanovaccine formulations, and as a bifunctional linker in pH-sensitive conjugates for siRNA delivery liposomes. HOOC-PEG2000-COOH can be used in research on thrombosis and atherosclerosis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
