139 Results for "

Genotoxicity

" in MedChemExpress (MCE) Product Catalog:
Products (139)

139 Results for "Genotoxicity" in MCE Product Catalog:

Cat. No.: HY-W776973
CAS No.: 1216449-31-8
Synonyms: Oxiranecarboxamide-13C3; 2,3-Epoxypropanamide-13C3
Glycidamide- 13C3 (Oxiranecarboxamide- 13C3) is the 13C-labeled Glycidamide (HY-119329). Glycidamide is the genotoxic metabolite of Acrylamide. Glycidamide can react with proteins, such as hemoglobin, or with DNA, and induces genotoxic effects .
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Cat. No.: HY-133647
CAS No.: 3039-13-2
Target:  

Others

Research Areas:  

Others

Dibromoacetaldehyde, a halogenated product, is a byproduct in drinking water and has genotoxicity .
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Cat. No.: HY-W103488
CAS No.: 1698-60-8
Research Areas:  

Others

Chloridazon is a herbicide with an LD50 value of 76.6 ppm at genotoxicity assay .
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Cat. No.: HY-133649
CAS No.: 64316-11-6
Target:  

Drug Derivative

Research Areas:  

Others

Dibromochloroacetaldehyde belongs to trihalogenated acetaldehyde and is a byproduct in drinking water. Dibromochloroacetaldehyde has genotoxicity .
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Cat. No.: HY-122099
CAS No.: 23246-96-0
Riddelline, a pyrrolizidine alkaloid, is a potent genotoxic agent. Riddelline induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver .
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Cat. No.: HY-136375S
CAS No.: 1190003-29-2
Cyanazine-d5 is deuterium labeled Cyanazine. Cyanazine, a triazine herbicide cyanazine, is used to control a variety of grass weeds and broadleaf weed. Cyanazine is proved non-genotoxic .
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Cat. No.: HY-154958
CAS No.: 3033409-34-3
Target:  

mTOR

Research Areas:  

Neurological Disease

mTOR inhibitor-12 (Compound 11) is a selective brain penetrant mTOR inhibitor without genotoxicity risk. mTOR inhibitor-12 can be used for the research of CNS diseases .
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Cat. No.: HY-131102R
CAS No.: 13297-17-1
Research Areas:  

Infection

Mequindox (Standard) is the analytical standard of Mequindox. This product is intended for research and analytical applications. Mequindox is an antimicrobial agent . Mequindox acts as an inhibitor of DNA synthesis. Mequindox induces genotoxicity and carcinogenicity in mice .
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Cat. No.: HY-136375R
CAS No.: 21725-46-2
Research Areas:  

Others

Cyanazine (Standard) is the analytical standard of Cyanazine. This product is intended for research and analytical applications. Cyanazine, a triazine herbicide cyanazine, is used to control a variety of grass weeds and broadleaf weed. Cyanazine is proved non-genotoxic .
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Cat. No.: HY-W612269S
Isonicotinoyl chloride-d4 is the deuterated labeled Isonicotinoyl chloride (HY-W612269). N-Acetylglycine (Aceturic acid) is a minor constituent of numerous foods with no genotoxicity or acute toxicity. N-acetylglycine is used in biological research of peptidomimetics .
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Cat. No.: HY-151628
CAS No.: 2797066-17-0
Target:  

Bacterial

Research Areas:  

Cancer

MRV03-068 (Compound 2) is a selective colibactin-activated peptidase (ClbP) inhibitor that blocks the genotoxic effect of Colibactin (HY-145930) on eukaryotic cells. MRV03-068 can be used in colorectal cancer research .
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Cat. No.: HY-W726390
CAS No.: 134720-04-0
Target:  

Adrenergic Receptor

Research Areas:  

Neurological Disease

2-(4-(2-Hydroxy-3-(isopropyl(nitroso)amino)propoxy)phenyl)acetamide is a genotoxic derivative of Atenolol (HY-17498) that can induce DNA fragmentation in rat hepatocytes when used at concentrations ranging from 0.1 to 1 mM.
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Cat. No.: HY-124489S1
CAS No.: 221093-33-0
2-Hydroxyestradiol-d5 is the deuterium labeled 2-Hydroxyestradiol. 2-Hydroxyestradiol, a metabolite of 17β-estradiol with minimal estrogenic activity, possesses antioxidant effects and reacts with DNA to form stable adducts and exerts genotoxicity[ .
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Cat. No.: HY-124489S
2-Hydroxyestradiol- 13C6 is the 13C-labeled 2-Hydroxyestradiol. 2-Hydroxyestradiol, a metabolite of 17β-estradiol with minimal estrogenic activity, possesses antioxidant effects and reacts with DNA to form stable adducts and exerts genotoxicity .
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Cat. No.: HY-W100026S
Galaxolide-d6 (mixture of diastereomers) (>80%) is the deuterium labeled Galaxolide (HY-W100026). Galaxolide can induce estrogenic activity (Estrogen Receptor/ERR), trigger oxidative stress and genotoxicity, and induce EROD and GST (Glutathione S-transferase) enzyme activity .
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Cat. No.: HY-124489R
CAS No.: 362-05-0
2-Hydroxyestradiol (Standard) is the analytical standard of 2-Hydroxyestradiol. This product is intended for research and analytical applications. 2-Hydroxyestradiol, a metabolite of 17β-estradiol with minimal estrogenic activity, possesses antioxidant effects and reacts with DNA to form stable adducts and exerts genotoxicity .
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Cat. No.: HY-B1244R
CAS No.: 551-92-8
Synonyms: 1,2-Dimethyl-5-nitroimidazole (Standard)
Research Areas:  

Infection

Dimetridazole (Standard) is the analytical standard of Dimetridazole (HY-B1244). This product is intended for research and analytical applications. Dimetridazole is a nitroimidazole antibiotic. Dimetridazole inhibits protein synthesis in cultures of Campylobacter jejuni. Dimetridazole is genotoxic. Dimetridazole can be used in the research of protozoal and bacterial infections .
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Cat. No.: HY-130053
CAS No.: 3771-19-5
Synonyms: SU-13-437
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

Nafenopin (SU-13-437) is a peroxidase proliferator with liver tumor promoting activity. Nafenopin is also used as an anti-hyperlipoproteinemia compound. Nafenopin is able to induce oxidative stress in vivo, showing its effects on the liver. The mechanism of action of nafenopin has differentiated features compared to other non-genotoxic carcinogens .
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Cat. No.: HY-146121
CAS No.: 1845720-46-8
Target:  

Bacterial

Research Areas:  

Infection

Antitubercular agent-26 (Compound 32) is an orally active anti-tubercular agent with an extracellular IC50 of 0.50 μM and an intracellular IC50 of 0.51 μM against M. tuberculosis H37Rv. Antitubercular agent-26 shows good metabolic stability, low risk of cardiotoxicity and no genotoxicity .
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Cat. No.: HY-W795264
CAS No.: 66508-32-5
Target:  

Parasite

Research Areas:  

Infection

FR900098 is an antimalarial agent that inhibits 1-deoxy-d-xylulose-5-phosphate (DXP) reductoisomerase. FR900098 has no significant acute toxicity or genotoxicity, and does not have the ability to cause chromosome breakage or heterogeneity. FR900098 has no effect on bone marrow red blood cells in NMRI mice .
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