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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
83 Results for "
V2
" in MedChemExpress (MCE) Product Catalog:
Products (83)
83 Results for "V2" in MCE Product Catalog:
Cat. No.: HY-186040
CAS No.: 790694-26-7
Target:
Research Areas:
ASP-7035 (compound 55) is an arginine vasopressin V2 receptor agonist. ASP-7035 can be used in the research of nocturia .
Cat. No.: HY-L0122V
1,122 compounds
Several CNS multi-parameter scoring approaches have been reported: CNS-MPO, CNS-MPO V.2, CNS-TEMPO, which suggesting an algorithm to predict CNS-ike properties of new chemical entities. We have applied these scoring algorithms to select macrocycles satisfying multiple cut-offs and structural desirability criteria. The resulting set consists of 1,122 macrocyclic compounds with CNS-MPO > 4, CNS-MPO.v2 > 4, and CNS-TEMPO < 4 for CNS-related drug discovery and research.
Cat. No.: HY-19880
CAS No.: 813426-25-4
Target:
Research Areas:
RWJ-676070 is a dual vasopressin V(1A)/V(2) receptor antagonist with an Ki value of 1.4 nM and 14 nM respectly .
Cat. No.: HY-17000A
CAS No.: 331947-66-1
Synonyms: (R)-(+)-OPC-41061
Target:
Research Areas:
(R)-(+)-Tolvaptan ((R)-(+)-OPC-41061) is the (R)-(+) enantiomer of Tolvaptan (HY-17000). Tolvaptan (OPC-41061) is a selective, competitive and orally active vasopressin receptor 2 (V2R) antagonist [2].
Cat. No.: HY-P5214
Research Areas:
Cat. No.: HY-112605
CAS No.: 2241025-50-1
Target:
Research Areas:
sPLA2-X Inhibitor 31 is a selective secreted phospholipase A2 type X (sPLA2-X) inhibitor with IC50s of 26 nM, 310 nM, and 2230 nM for sPLA2-X, sPLA2-IIa, and sPLA2-V, respectively .
Cat. No.: HY-P990986
CAS No.: 2922216-49-5
Target:
Research Areas:
Cat. No.: HY-P990992
CAS No.: 2922216-50-8
Synonyms: GI-102
Target:
Research Areas:
Cat. No.: HY-180142
Target:
Research Areas:
XYDC2050 (Compound 29) is a selective vasopressin V2 receptor (V2R) antagonist with an IC50 of 27 nM and a Ki of 2.8 nM. XYDC2050 shows a Ki of 420.7 nM (SI = 162 fold) for V1R. XYDC2050 can inhibit Vasopressin (HY-B1811)-induced intracellular cyclic adenosine monophosphate (cAMP) accumulation with an IC50 of 12 nM. XYDC2050 can inhibit the growth of renal cysts, reduce the ratio of kidney weight to body weight and decrease the area of cysts and the cystic index. XYDC2050 can be used for the research of autosomal dominant polycystic kidney disease (ADPKD) .
Cat. No.: HY-105685R
CAS No.: 512784-93-9
Research Areas:
SRX246 (Standard) is the analytical standard of SRX246 (HY-105685). This product is intended for research and analytical applications. SRX246 is a potent, BBB-penetrant, highly selective vasopressin 1a (V1a) receptor antagonist (Ki=0.3 nM for human V1a). SRX246 has no interaction at V1b and V2 receptors. SRX246 also displays negligible binding at 64 others receptors classes, including 35 G-proteincoupled receptors. SRX246 can be used for treatment of stress-related disorders .
Cat. No.: HY-165456
CAS No.: 134892-42-5
Research Areas:
AGN-190851 is a potent and selective agonist of α2-adrenergic receptor (α2 adrenoceptor). AGN-190851 induces dose-dependent water diuresis in rats, and inhibits vasopressin V2 receptor in a species-dependent manner in vitro, thereby suppressing cAMP production. AGN-190851 enhances the contraction of porcine myometrium. AGN 190851 can be used in studies on renal diuretic mechanisms, pharmacology of α2-adrenergic receptor subtypes, and parturition [2].
Cat. No.: HY-P71411
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: UBE2V2; Ubiquitin Conjugating Enzyme E2 V2; Ubiquitin-Conjugating Enzyme E2 Variant 2; EDPF-1; EDAF-1; MMS2; UEV2; DDVit-1; DDVIT1; UEV-2; EDPF1; Enterocyte Differentiation-Associated Factor 1; Enterocyte Differentiation-Promoting Factor 1; Vitamin D3-Ind
Species:
Human
Source:
E. coli
Cat. No.: HY-W009724R
CAS No.: 524-95-8
Synonyms: 2-APB (Standard)
Research Areas:
2-Aminoethyl diphenylborinate (Standard) is the analytical standard of 2-Aminoethyl diphenylborinate (HY-W009724). This product is intended for research and analytical applications. 2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of Inositol triphosphate receptor (IP3R). 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca 2+ (SOC) channel and activates some TRP channels (V1, V2 and V3). Additionally, 2-Aminoethyl diphenylborinate has inhibitory effects on vasospasm. At high concentrations, it exhibits specific anti-inflammatory and antioxidant effects in neural tissue [2] .
Cat. No.: HY-P701763
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PXK; Modulator Of Na,K-ATPase Long Form; PX Domain Containing Serine/Threonine Kinase Like; PX Serine/Threonine Kinase; PX Domain-Containing Protein Kinase-Like Protein; PX Ser/Thr Kinase V2; Slob; PXK Protein; Modulator Of Na,K-ATPase; MONAKA; FLJ20335;
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P704083
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: UBE2V2; Ubiquitin Conjugating Enzyme E2 V2; Ubiquitin-Conjugating Enzyme E2 Variant 2; EDPF-1; EDAF-1; MMS2; UEV2; DDVit-1; DDVIT1; UEV-2; EDPF1; Enterocyte Differentiation-Associated Factor 1; Enterocyte Differentiation-Promoting Factor 1; Vitamin D3-Inducible Protein; MMS2 Homolog; DDVit 1; CDNA,FLJ93989,Homo Sapiens Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2),MRNA; Methyl Methanesulfonate Sensitive 2,S.Cerevisiae,Homolog Of; Ubiquitin-Conjugating Enzyme E2 Variant 2,Isoform CRA_a; Enterocyte Differentiation-Associated Factor EDAF-1; Enterocyte Differentiation Promoting Factor 1 Alpha,25-Dihydroxyvitamin D3-Inducible
Species:
Human
Source:
E. coli
Cat. No.: HY-P704084
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: UBE2V2; Ubiquitin Conjugating Enzyme E2 V2; Ubiquitin-Conjugating Enzyme E2 Variant 2; EDPF-1; EDAF-1; MMS2; UEV2; DDVit-1; DDVIT1; UEV-2; EDPF1; Enterocyte Differentiation-Associated Factor 1; Enterocyte Differentiation-Promoting Factor 1; Vitamin D3-Inducible Protein; MMS2 Homolog; DDVit 1; CDNA,FLJ93989,Homo Sapiens Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2),MRNA; Methyl Methanesulfonate Sensitive 2,S.Cerevisiae,Homolog Of; Ubiquitin-Conjugating Enzyme E2 Variant 2,Isoform CRA_a; Enterocyte Differentiation-Associated Factor EDAF-1; Enterocyte Differentiation Promoting Factor 1 Alpha,25-Dihydroxyvitamin D3-Inducible
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P704082
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: UBE2V2; Ubiquitin Conjugating Enzyme E2 V2; Ubiquitin-Conjugating Enzyme E2 Variant 2; EDPF-1; EDAF-1; MMS2; UEV2; DDVit-1; DDVIT1; UEV-2; EDPF1; Enterocyte Differentiation-Associated Factor 1; Enterocyte Differentiation-Promoting Factor 1; Vitamin D3-Inducible Protein; MMS2 Homolog; DDVit 1; CDNA,FLJ93989,Homo Sapiens Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2),MRNA; Methyl Methanesulfonate Sensitive 2,S.Cerevisiae,Homolog Of; Ubiquitin-Conjugating Enzyme E2 Variant 2,Isoform CRA_a; Enterocyte Differentiation-Associated Factor EDAF-1; Enterocyte Differentiation Promoting Factor 1 Alpha,25-Dihydroxyvitamin D3-Inducible
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P11702
Cat. No.: HY-P11701
CAS No.: 681020-80-4
Cat. No.: HY-P705083
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Spike; S protein; Spike glycoprotein; S glycoprotein; B.1.351; 20H/501Y.V2
Species:
Virus
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
