10042 Results for "

multi-function agents,

" in MedChemExpress (MCE) Product Catalog:
Products (10042)

10042 Results for "multi-function agents," in MCE Product Catalog:

33
33 Cited Publications
Cat. No.: HY-12033
CAS No.: 362-07-2
Purity:  99.76%
Synonyms: 2-ME2; NSC-659853
2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa .
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32
32 Cited Publications
Cat. No.: HY-17459
CAS No.: 120202-66-6
Synonyms: (S)-(+)-Clopidogrel bisulfate; (S)-(+)-Clopidogrel hydrogen sulfate
Research Areas:  

Cardiovascular Disease Cancer

Clopidogrel hydrogen sulfate is an antiplatelet agent to prevent blood clots. Clopidogrel hydrogen sulfate inhibits CYP2B6 and CYP2C19 with IC50s of 18.2 nM and 524 nM, respectively . Clopidogrel hydrogen sulfate is a potent antithrombotic agent that inhibits ADP-induced platelet aggregation .Clopidogrel hydrogen sulfate also is an orally active P2Y(12) inhibitor .
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31
31 Cited Publications
Cat. No.: HY-B0332
CAS No.: 58-27-5
Synonyms: Vitamin K3
Menadione is a naphthoquinone that is converted into active vitamin K2 in the body. Menadione is a potential anticancer agent and radiosensitizer .
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31
31 Cited Publications
Cat. No.: HY-B0221
CAS No.: 1397-89-3
Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.
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31
31 Cited Publications
Cat. No.: HY-50879
CAS No.: 143664-11-3
Synonyms: GF120918; GW0918; GG918; GW120918
Target:  

P-glycoprotein BCRP

Research Areas:  

Cancer

Elacridar is an orally active P-glycoprotein (Pgp) and breast cancer resistance protein (BCRP) inhibitor. Elacridar can be used to examine the influence of efflux transporters on agent distribution to brain and the research of cancer .
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31
31 Cited Publications
Cat. No.: HY-50880
CAS No.: 143851-98-3
Synonyms: GF120918A
Target:  

P-glycoprotein BCRP

Research Areas:  

Cancer

Elacridar hydrochloride (GF120918A) is an orally active P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) inhibitor. Elacridar hydrochloride can be used to examine the influence of efflux transporters on agent distribution to brain and it can be used for the research of cancer .
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30
30 Cited Publications
Cat. No.: HY-16980A
CAS No.: 1334714-66-7
Synonyms: TP-434 dihydrochloride; TP-434-046
Research Areas:  

Infection

Eravacycline dihydrochloride (TP-434 dihydrochloride) is a potent and broad-spectrum antibacterial agent.
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30
30 Cited Publications
Cat. No.: HY-B0105
CAS No.: 65277-42-1
Synonyms: Ketoconazol; R 41400
Research Areas:  

Infection Cancer

Ketoconazole (R-41400) is an imidazole anti-fungal agent, a CYP3A4 and CYP24A1 inhibitor.
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30
30 Cited Publications
Cat. No.: HY-10007
CAS No.: 284035-33-2
Purity:  99.94%
Synonyms: SB-262470A
Target:  

CaSR

Research Areas:  

Metabolic Disease

NPS-2143 (SB-262470A), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 (SB-262470A) blocks increases in cytoplasmic Ca 2+ concentrations (IC50=43 nM) elicited by activating the Ca 2+ receptor in HEK 293 cells expressing the human Ca 2+ receptor .
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30
30 Cited Publications
Cat. No.: HY-10171
CAS No.: 324523-20-8
Purity:  99.98%
Synonyms: SB-262470A hydrochloride
Target:  

CaSR

Research Areas:  

Metabolic Disease

NPS-2143 hydrochloride (SB-262470A hydrochloride), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 hydrochloride (SB-262470A hydrochloride) blocks increases in cytoplasmic Ca 2+ concentrations (IC50=43 nM) elicited by activating the Ca 2+ receptor in HEK 293 cells expressing the human Ca 2+ receptor .
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29
29 Cited Publications
Cat. No.: HY-B0284
CAS No.: 21829-25-4
Synonyms: BAY-a-1040
Research Areas:  

Cardiovascular Disease Cancer

Nifedipine (BAY-a-1040) is a potent calcium channel blocker and agent of choice for cardiac insufficiencies.
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29
29 Cited Publications
Cat. No.: HY-D0021
CAS No.: 1239-45-8
Synonyms: EtBr; Homidium bromide
EthD bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.
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28
28 Cited Publications
Cat. No.: HY-100561
CAS No.: 2226-96-2
Purity:  99.73%
Synonyms: 4-Hydroxy-TEMPO
Research Areas:  

Cancer

Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS).
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28
28 Cited Publications
Cat. No.: HY-W018746
CAS No.: 139-33-3
Synonyms: Ethylenediaminetetraacetic acid disodium
EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease.
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27
27 Cited Publications
Cat. No.: HY-N1150
CAS No.: 50-89-5
Synonyms: DThyd; NSC 21548
Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication .
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27
27 Cited Publications
Cat. No.: HY-W250119
CAS No.: 23411-34-9
Synonyms: EDTA disodium calcium salt hydrate; Ethylenediaminetetraacetic acid disodium calcium salt hydrate
Calcium disodium edetate hydrate (EDTA disodium calcium salt hydrate) is a metal chelator and antifungal agent. Calcium disodium edetate hydrate chelates Mn 2+, damages mitochondria, and interferes with carbohydrate metabolic pathways, particularly the synthesis of pyruvate in glycolysis. Calcium disodium edetate hydrate inhibits Penicillium digitatum and delays conidial germination. Calcium disodium edetate (hydrate) enhances the host defense system of citrus fruits. Calcium disodium edetate hydrate is applicable to research related to citrus green mold .
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26
26 Cited Publications
Cat. No.: HY-13518
CAS No.: 10083-24-6
Purity:  98.97%
Synonyms: Astringenin; trans-Piceatannol
Piceatannol is a well-known Syk inhibitor and reduces the expression of iNOS induced by TNF. Piceatannol is an effective agent for research of acute lung injury (ALI) . Piceatannol is a naturally occurring polyphenolic stilbene found in various fruits and vegetables and exhibits anticancer and anti-inflammatory properties . Piceatannol induces apoptosis in DLBCL cell lines . Piceatannol induces autophagy and apoptosis in MOLT-4 human leukemia cells .
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24
24 Cited Publications
Cat. No.: HY-Y0016
CAS No.: 81-88-9
Synonyms: Basic Violet 10; Brilliant Pink B; Rhodamine O; Tetraethylrhodamine
Rhodamine B is a staining fluorescent dye, commonly used for dyeing textiles, paper, soap, leather, and agents.
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24
24 Cited Publications
Cat. No.: HY-Y1890
CAS No.: 61791-12-6
Synonyms: Polyoxyethylene(40) Castor Oil; PEG-40 Castor Oil
Cremophor EL-40, a polyoxyethylene castor oil derivative, is a nonionic surfactant. Cremophor EL-40 is widely employed to improve dissolution and delivery of agents .
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24
24 Cited Publications
Cat. No.: HY-18777
CAS No.: 927822-86-4
Research Areas:  

Cancer

KC7F2 is a potent hypoxia inducible factor-1 (HIF-1) pathway inhibitor with an IC50 of 20 μM in LN229-HRE-AP cells, and with potential as a cancer therapy agent .
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